您的位置：首页 > 技术文献 > 产品说明 > MCM2 Antibody (Center) Catalog Number：OM213424
| Product Name | MCM2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB~~1:50~100 FC~~1:10~50: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
| Gene Synonyms | More |
|---|---|
| Alternative Names | More |
| Molecular Weight(MW) | 101896 Da |
| Function | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ＇once per cell cycle＇ DNA replication initiation ａnd elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase ａnd for cell division More |
| Tissue Specificity | This MCM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495~524 amino acids from the Center region of human MCM2. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 4171 |
|---|
Western blot analysis of MCM2 Antibody (Center) in 293 cell line lysates (35ug/lane). MCM2 (arrow) was detected using the purified Pab.
MCM2 Antibody (Center) flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell ( histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
| Application Notes | WB~~1:50~100 FC~~1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
① 凡本网注明"来源：易推广"的所有作品，版权均属于易推广，未经本网授权不得转载、摘编或利用其它方式使用。已获本网授权的作品，应在授权范围内
使用，并注明"来源：易推广"。违者本网将追究相关法律责任。② 本信息由注册会员：上海笃玛生物科技有限公司 发布并且负责版权等法律责任。
易推广客服微信
