标题MCM2 antibody Catalog Number：OM262648

提供者：上海笃玛生物科技有限公司发布时间：2024/9/27 阅读次数：19次 >>进入该公司展台

Product Name	MCM2 antibody
Antibody Type	Primary Antibodies
Product description	Mouse Monoclonal Antibody [2B3] to MCM2The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) ａnd may be involved in the formation of replication forks ａnd in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, ａnd 7, ａnd has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, ａnd thus regulated by, protein kinases CDC2 ａnd CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012] More
Immunogen	The immunogen corresponding to human MCM2 expressed in E. Coli.

Gene Synonyms	CDCL1 D3S3194 BM28 MITOTIN CCNL1 CDC19 More
Target	MCM2
Molecular Weight(MW)	125 kDa (note)

Application

ELISA analysis of MCM2 antibody [2B3] using control (100 ng) ａnd antigen (10 ng, 50 ng, 100 ng).
Application

WB analysis of PC-12 (1), Cos7 (2), NIH3T3 (3), HepG2 (4), HEK293 (5), K562 (6), Jurkat (7), HeLa (8) ａnd MCF-7 (9) cell lysates using MCM2 antibody [2B3].
Application

FACS analysis of HeLa cells using MCM2 antibody [2B3] (blue) ａnd a negative control (red).
Application

IHC-P analysis of colon cancer tissues using MCM2 antibody [2B3].