标题PINCH antibody Catalog Number：OM268604

提供者：上海笃玛生物科技有限公司发布时间：2024/9/29 阅读次数：21次 >>进入该公司展台

Product Name	PINCH antibody
Antibody Type	Primary Antibodies
Product description	Mouse Monoclonal Antibody [5G7] to PINCHThe protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] More
Immunogen	The immunogen corresponding to human PINCH expressed in E. Coli.

Application

ICC/IF analysis of HepG2 cells using PINCH antibody [5G7] (green), Alexa Fluor-555 phalloidin (red) ａnd DRAQ5 fluorescent DNA dye (blue).
Application

WB analysis of (1) A549, (2) Jurkat ａnd (3) HeLa lysates using PINCH antibody [5G7].
Application

WB analysis of human PINCH (a.a. 87-249) recombinant protein using PINCH antibody [5G7].
Application

ELISA analysis of control antigen ａnd antigen using PINCH antibody [5G7].
Application

FACS analysis of Hela cells using PINCH antibody [5G7] (blue) or a negative control (red).