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| Product Name | Pinch-1/2 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor ａnd integrin signaling pathway. Pinch is involved in cell differentiation, proliferation ａnd survival by acting as an effector of integrin ａnd growth factor signaling. It is a cylasmic protein expressed in most tissues ａnd consists of five LIM domains, a nuclear localization signal ａnd a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Pinch-1 ａnd Pinch-2 of mouse, rat ａnd human origin by WB, IP, IF ａnd ELISA; also reactive with additional species, including equine, canine, bovine, porcine ａnd avian: | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | |
|---|---|
| Tissue Specificity | epie corresponding to amino acids 1-300 mapping at the N-terminus of Pinch-1 of human origin |
| Entrez Gene | 3987 |
|---|
Western blot analysis of Pinch-1/2 expression in T98G (A) ａnd COLO 320DM (B) whole cell lysates.
Western blot analysis of Pinch-1/2 expression in human platelets whole cell lysate.
| Application Notes | recommended for detection of Pinch-1 ａnd Pinch-2 of mouse, rat ａnd human origin by WB, IP, IF ａnd ELISA; also reactive with additional species, including equine, canine, bovine, porcine ａnd avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
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