标题DLGAP1 antibody Catalog Number：OM250145

提供者：上海笃玛生物科技有限公司发布时间：2024/9/29 阅读次数：2次 >>进入该公司展台

Product Profile

Product Name	DLGAP1 antibody
Antibody Type	Primary Antibodies
Product description	Rabbit polyclonal antibody to DLGAP1SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal ａnd signaling components, such as focal adhesion kinase (FAK) ａnd proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 ａnd -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse ａnd is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins. More

Product Name

DLGAP1 antibody

Antibody Type

Primary Antibodies

Product description

Rabbit polyclonal antibody to DLGAP1SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal ａnd signaling components, such as focal adhesion kinase (FAK) ａnd proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 ａnd -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse ａnd is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.
More

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	ELISAICC/IFIHC-PWB
	ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. More
Species Reactivity	Human
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Synonyms	Disks largeassociated protein1 DAP1 DAP-1 Disks large-associated protein 1 SAP90/PSD-95-associated protein 1 Disks largeassociated protein 1 SAPAP1 SAP90/PSD95associated protein 1 GKAP SAP90/PSD95associated protein1 DLGAP1 DAP 1 More
Target	DLGAP1
Tissue Specificity	This antibody is specific for DLGAP1

Application

Application

Immunohistochemistry of SAPAP1 in human brain with SAPAP1 antibody at 5 ug/ml.
Application

Immunofluorescence of SAPAP1 in Human Brain cells with SAPAP1 antibody at 20 ug/mL.
Application

Western blot analysis of SAPAP1 in human brain tissue lysate with SAPAP1 antibody at (A) 0.5 ａnd (B) 1 ug/ml.

Positive Control	Blocking Peptide:
Application Notes	ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. More

Additional Information

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	PBS containing 0.02% sodium azide

关键词：稳定性强特异性强灵敏度高

上一篇：DLGAP1 antibody, N-term Catalog Number：OM250147 下一篇：DLGAP1 Antibody (N-term) Catalog Number：OM231357

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标题DLGAP1 antibody Catalog Number：OM250145

Product Profile

Key Feature

Target Information

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Additional Information

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