标题SUMO2/3 Antibody Catalog Number：OM292543

SUMO2/3 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (Sumo-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, which is a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis ａnd protein stability. All SUMO proteins localize to the nucleus ａnd are covalently conjugated, affecting protein structure, function ａnd interactions. SUMO2 ａnd 3 are 96% identical ａnd are more mobile within nucleus relative to SUMO1. Specific functional differences between SUMO1 ａnd SUMO2 ａnd 3 remain to be identified.1) Kamitani T, Kito K, Nguyen HP, et al. Characterization of a second member of the sentrin family of ubiquitin-like proteins. J. Biol. Chem.1998;273:11349-53.
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SUMO2/3 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SUMO2. The immunogen is located within the last 50 amino acids of SUMO2/3.

ELISAIFIHC-PWB

HumanMouseRat