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您的位置:首页 > 技术文献 > 产品说明 > SUMO2/3 Antibody (Center) Catalog Number:OM222301

标题SUMO2/3 Antibody (Center) Catalog Number:OM222301

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/9/30   阅读次数:52次 >>进入该公司展台
 

Product Profile

Product Name SUMO2/3 Antibody (Center)
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WB

 
WB~~1:100~500:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Gene Synonyms
SMT3B
SMT3H1
Alternative Names
SUMO3
SMT3B
SMT3H1
Small ubiquitin-related modifier 3
SMT3 homolog 1
SUMO-2
Ubiquitin-like protein SMT3B
More 
Molecular Weight(MW) 11637 Da
Function
Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4
More 
Tissue Specificity Expressed predominantly in liver.
Cellular Localization Cylasm.

Database Links

Entrez Gene 6612

Application

  • Application

    The anti-SUMO2/3 Pab is used in Western blot to detect SUMO2/3 in Saos-2 cell lysate.

  • Application

    Western blot analysis of SUMO3 (arrow) using rabbit polyclonal SUMO2/3 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SUMO3 gene (Lane 2) (Origene Technologies).

Application Notes
WB~~1:100~500:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

关键词:稳定性强  特异性强    灵敏度高  

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