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T8873BractoppinDNA break,Bractoppin,phosphopeptide,inhibit,DNA/RNA Synthesis,DNA damage,RAD51,G2 arrest,I
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activity exploration suggests that Bractoppin engages BRCA1 tBRCT residues recognizing pSer in the consensus motif, pSer-Pro-Thr-Phe, plus an abutting hydrophobic pocket that is distinct in structurally related BRCT domains, conferring selectivity.
价 格：￥电议型 号：T8873产 地：中国大陆
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T32873Maralixibat Chloride
Maralixibat Chloride, an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.
价 格：￥电议型 号：T32873产 地：中国大陆
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T16873SERCA2a activator 1Ca channels,phospholamban,Inhibitor,Ca2+ channels,SERCA2a activator 1,SERCA2a,SER
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the systolic and diastolic functions of the heart.
价 格：￥电议型 号：T16873产 地：中国大陆
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T8924MFCD28987368MFCD28987368,ADC Linkers,inhibit,MFCD-28987368,Antibody-drug conjugates linkers,Inhibito
MFCD28987368 is a chemical compound
价 格：￥电议型 号：T8924产 地：中国大陆
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TN1873Lirinidineanticancer,Inhibitor,radical scavenge,antioxidant,cosmetic,Lirinidine,(+)-Lirinidine,inhib
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, arachidonic acid and platelet-activating factor-induced platelet aggregation.
价 格：￥电议型 号：TN1873产 地：中国大陆
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T8730BMS986260nuclear translocation,TGFβR1,BMS-986260,FOXP3 expression,MINK,Transforming growth factor be
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
价 格：￥电议型 号：T8730产 地：中国大陆
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T6873Lauric AcidInhibitor,Bacterial,Lauric Acid,Endogenous Metabolite,inhibit
Lauric Acid,which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone. It is a major component of coconut oil and palm kernel oil.
价 格：￥电议型 号：T6873产 地：中国大陆
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T12809(S)-PF-06873600(S)PF06873600,(S) PF 06873600
(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.
价 格：￥电议型 号：T12809产 地：中国大陆
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T8463PF-06873600PF06873600,PF 06873600
PF-06873600 is a selective and orally bioavailable cyclin-dependent kinase (CDK) inhibitor(CDK2, CDK4 and CDK6 with Ki of 0.09 nM, 0.13 nM and 0.16 nM, respectively), has potential antineoplastic activity.
价 格：￥电议型 号：T8463产 地：中国大陆
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T7873IberverinIberverin
Iberverin is a naturan product. It induces phase II enzyme activity and decreases expression of androgen receptors in prostate cancer cells.
价 格：￥电议型 号：T7873产 地：中国大陆
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T9008NPD8733Inhibitor,inhibit,ATPase,p97,fibroblast,cancer,NPD 8733,NPD8733,VCP,migration,NPD-8733
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. It specifically binds to valosin-containing protein (VCP)/p97.
价 格：￥电议型 号：T9008产 地：中国大陆
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T8738LUN42518 HCl 47142-51-8(free base)LUN-42518 HCl 47142-51-8(free base),LUN42518 HCl 47142 51 8(fre
LUN42518 HCl is an analogue of phentolamine. Phentolamine is a nonselective alpha-adrenergic antagonist.
价 格：￥电议型 号：T8738产 地：中国大陆
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T11079NMI 8739
NMI 8739 is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
价 格：￥电议型 号：T11079产 地：中国大陆
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T8737GR 125743h5-HT1B,cognitive disorder,h5-HT1D,cardiovascular,GR-125743,GR125743,inhibit,Parkinson’s di
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
价 格：￥电议型 号：T8737产 地：中国大陆
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T8732CTPI-2macrophage,carrier,CTPI-2,NSCLC,transporter,glucose,steatohepatitis,CTPI 2,Mitochondrial Metab
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.
价 格：￥电议型 号：T8732产 地：中国大陆
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T8734Cholineapoptosis,orally active,inhibit,hydrogen oxidized,organic base,sphingomyelin,Choline,standard
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins
价 格：￥电议型 号：T8734产 地：中国大陆
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T8733Antrodin AAntrodin A,inhibit,Inhibitor,anti-inflammatory,acute alcoholic liver injury,antioxidant
Antrodin A (AdA) is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflammatory capacity of the liver and maintaining the stability of the intestinal flora.
价 格：￥电议型 号：T8733产 地：中国大陆
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T28362PF-02413873nonsteroidal,inhibit,PF 2413873,Progesterone Receptor,endometrial,PF-2413873,nuclear,PF 0
PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM. PF-02413873 can be used in studies about the treatment of gynecological conditions such as endometriosis.
价 格：￥电议型 号：T28362产 地：中国大陆
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T58732,6-Dihydroxybenzoic acid
2,6-Dihydroxybenzoic acid is a secondary metabolite of salicylic acid which has been hydrolyzed by liver enzymes during phase I metabolism.
价 格：￥电议型 号：T5873产 地：中国大陆
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T5398BMS 599626 2HCl (873837-23-1(HCl))AC480 dihydrochloride
BMS-599626 (AC480) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.
价 格：￥电议型 号：T5398产 地：中国大陆
