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产品数：86101
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T9100BP 897inhibit,BP-897,BP897,cocaine drug-seeking,BP 897,Dopamine Receptor,Inhibitor,addiction,behavio
2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors, and shows low affinities at D1 and D4 receptors (Kis, 3 and 0.3 μM, respectively).
价 格：￥电议型 号：T9100产 地：中国大陆
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T8976PD-089828EGFR,ATP,nonselective,PD 089828,PDGFR,autophosphorylation,PD089828,HER1,Epidermal growth fa
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)
价 格：￥电议型 号：T8976产 地：中国大陆
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T8973HS-1793HIF-1α,Inhibitor,MCF-7,HS 1793,breast cancer,inhibit,ERK,HCT116,resveratrol,VEGF,Apoptosis,HS
HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model
价 格：￥电议型 号：T8973产 地：中国大陆
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T67854BAS 00489700
BAS 00489700 is a N-UTR interaction inhibitor. BAS 00489700 inhibits virus replication in cell culture.
价 格：￥电议型 号：T67854产 地：中国大陆
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T7502LPF 05089771Na+ channels,diabetic,inhibit,Inhibitor,neuropathy,Sodium Channel,Na channels,TTX-R,PF 05
PF-05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
价 格：￥电议型 号：T7502L产 地：中国大陆
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T8974ML-211MAGL,ML 211,inhibit,Phospholipase,Monoacylglycerol lipase,ML-211,Inhibitor,ML211
ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)
价 格：￥电议型 号：T8974产 地：中国大陆
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T8970ML162p62,Glutathione Peroxidase,GPX4,ML-162,Nrf2,anticancer,HRAS,Ferroptosis,Inhibitor,inhibit,ML 16
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)
价 格：￥电议型 号：T8970产 地：中国大陆
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T28072MLN-3897
MLN-3897 is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation.
价 格：￥电议型 号：T28072产 地：中国大陆
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T7897PK150Bacterial,MRSA,MSSA,Gram-positive,PK-150,antibacterial,PK 150,PK150,Inhibitor,VISA,inhibit
PK150 shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations.
价 格：￥电议型 号：T7897产 地：中国大陆
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TP1897L1JIP-1 (153-163) acetate(438567-88-5 free base)JIP1 (153163) acetate(438567885 free base),JIP 1 (153
Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.
价 格：￥电议型 号：TP1897L1产 地：中国大陆
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T8975PSB-SB-487GPR55,PSB SB 487,Inhibitor,G protein-coupled receptor 55,PSBSB487,Parkinson disease,cancer
PSB-SB-487 is antagonist of GPR55.
价 格：￥电议型 号：T8975产 地：中国大陆
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T8972FIT-039Cytomegalovirus,HSV-1,Herpes simplex virus,transcription,Inhibitor,DNA,CDK,Cyclin dependent k
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
价 格：￥电议型 号：T8972产 地：中国大陆
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T7502PF 05089771 tosylatePF 05089771 tosylate,TTX-R,pain,Na channels,PF-05089771,neuropathy,diabetic,Sodi
PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8 channels (IC50: 0.11-25 μM), L-type calcium, and KvLQT and hERG potassium channels (IC50: ≥10 μM), as well as human and cynomolgus monkey TRPV1 receptors (IC50: 10/20 μM). PF-05089771 is also 1, 000-fold selective for half-inactivated over resting Nav1.7 channels, and mutation o
价 格：￥电议型 号：T7502产 地：中国大陆
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T88972-Iodoacetamidealkylation,2-Iodoacetamide,Inhibitor,cysteine,2Iodoacetamide,alkylating,protein,2 Iod
2-Iodoacetamide is an alkylating agent, and is a commonly used agent for alkylation of cysteine during sample preparation for proteomics.
价 格：￥电议型 号：T8897产 地：中国大陆
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T8979AEM1AEM-1,AEM1,inhibit,AEM 1,Inhibitor,Keap1-Nrf2
AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.
价 格：￥电议型 号：T8979产 地：中国大陆
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T8978DD1DD 1,P70S6K degradation,Bax activation,mitochondrial membrane depolarization,S6K,proteasome inhib
DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
价 格：￥电议型 号：T8978产 地：中国大陆
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T8971ImidazenilImidazenil
Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.
价 格：￥电议型 号：T8971产 地：中国大陆
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T98977-Methoxy-1-naphthaleneacetic acid7Methoxy1naphthaleneacetic acid,7 Methoxy 1 naphthaleneacetic acid
7-Methoxy-1-naphthaleneacetic acid is an inhibitor of auxin action in plants. 7-Methoxy-1-naphthaleneacetic acid inhibits polar auxin transport and tropic responses associated with asymmetric auxin distribution in Arabidopsis and maize. 7-Methoxy-1-naphthaleneacetic acid inhibits auxin transport mediated by AUX1, PIN, and ABCB proteins expressed in yeast.
价 格：￥电议型 号：T9897产 地：中国大陆
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T6897Monomethyl auristatin ESGD1010,Microtubule/Tubulin,SGD 1010,Apoptosis,Monomethyl auristatin E,inhibi
Monomethyl auristatin E (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.
价 格：￥电议型 号：T6897产 地：中国大陆
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T5S1897Linderalactone
1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.
价 格：￥电议型 号：T5S1897产 地：中国大陆
