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产品数:86101
参观次数:3249820
已选条件
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TN1911MareinGLUT1,HDAC,Inhibitor,Akt,inhibit,antioxidative,Marein,Histone deacetylases,antihypertensive,AM
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy.
价 格:¥电议型 号:TN1911产 地:中国大陆
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TWP2911ThymidineThymidine,precursor,synchronizing,inhibit,NSC21548,DNA,NSC-21548,Inhibitor,replication,arre
1. Thymidine overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
价 格:¥电议型 号:TWP2911产 地:中国大陆
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T9115Vanillic AcidNuclear factor-κB,Vanillic Acid,NF-κB,inhibit,Bacterial,Nuclear factor-kappaB,Endogenou
Vanillic acid is used as a condiment in food,which used in wine and vinegar. It is an intermediate in the production of vanillin from ferulic acid.
价 格:¥电议型 号:T9115产 地:中国大陆
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T8911methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylatemethyl 5(3,4dimethoxyphenyl)isoxazole3carboxyla
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate is a biochemical.
价 格:¥电议型 号:T8911产 地:中国大陆
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TP1911LCALP3 acetate(261969-05-5 free base)CALP-3 acetate(261969-05-5 free base),CALP3 acetate(261969055 fr
CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps.
价 格:¥电议型 号:TP1911L产 地:中国大陆
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T9113MyristicinMyristicin,Serotonin Receptor,Inhibitor,5-hydroxytryptamine Receptor,5-HT Receptor,inhibit
Myristicin is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin may antagonize the anxiolytic effects of midazolam, increase anxiety, and affect motor movements. Myristicin can induce apoptosis as characterised by alterations i
价 格:¥电议型 号:T9113产 地:中国大陆
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T9230KM 91104V-ATPase human HSC,a3-b2 subunits,KM-91104,KM 91104,Inhibitor,KM91104,Proton Pump,cell-perme
KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.
价 格:¥电议型 号:T9230产 地:中国大陆
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T7424NDI-091143NDI 091143,ACLY,inhibit,ATP Citrate Lyase,NDI-091143,NDI091143,Inhibitor
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
价 格:¥电议型 号:T7424产 地:中国大陆
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T9787suvn-911nicotinic,antidepressant,nAChR,acetylcholine,neuronal,Inhibitor,SUVN-911,suvn911,suvn 911,de
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.
价 格:¥电议型 号:T9787产 地:中国大陆
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T29114VRT-532
VRT-532 is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag) in cystic fibrosis, and modification of CFTR by small molecule modulator VRT-532 can increase ARSB and reduce the accumulation of 4-chondroitin sulfate.
价 格:¥电议型 号:T29114产 地:中国大陆
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T91118-Azaadenosinethyroid,inhibit,editing,LIN28B,invasion,proliferation,Cal62,migration,8Azaadenosine,RN
8-Azaadenosine is a potent ADAR1 inhibitor and an A-to-I editing inhibitor. It blocks RNA editing and inhibits proliferation, 3D growth, invasion, and migration in thyroid cancer cells.
价 格:¥电议型 号:T9111产 地:中国大陆
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T9118KEA1-97Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,I
Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity of thioredoxin.
价 格:¥电议型 号:T9118产 地:中国大陆
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T9119SU0268MCF-7,Inhibitor,cGAS,OGG1,SU0268,A549,SU 0268,STING,IRF3,inhibit,HeLa,glycosylase,antibacteria
SU0268 is a potent and specific 8-Oxoguanine DNA glycosylase 1 (OGG1) inhibitor. SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection.
价 格:¥电议型 号:T9119产 地:中国大陆
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T9911TocilizumabCOVID-19,IL-6R,Anti-Human IL6R, Humanized Antibody,rheumatoid,respiratory failure,antibod
Tocilizumab anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
价 格:¥电议型 号:T9911产 地:中国大陆
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T9117BSJ-4-116CDK,degrader,antiproliferative,inhibit,Kelly,C1039F,BSJ 4 116,Cyclin dependent kinase,PROTA
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
价 格:¥电议型 号:T9117产 地:中国大陆
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T39113LPovorcitinib phosphateJAK,Povorcitinib,Povorcitinib phosphate,CLE,Janus kinase,JAK1 inhibitor,Inhibi
Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.
价 格:¥电议型 号:T39113L产 地:中国大陆
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T9114β-CaryophylleneβCaryophyllene,Cannabinoid Receptor,β-Caryophyllene,β Caryophyllene,Endogenous Metabo
β-Caryophyllene acts as an CB2 receptor agonist.
价 格:¥电议型 号:T9114产 地:中国大陆
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T9116SMCCSMCC,ADC Linkers,inhibit,Antibody-drug conjugates linkers,Inhibitor
N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC), also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker.
价 格:¥电议型 号:T9116产 地:中国大陆
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T6911NSC-87877 disodiumApoptosis,Neuroblastoma,inhibit,Inhibitor,NSC 87877 disodium,PPAR,p53,Phosphatase,
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
价 格:¥电议型 号:T6911产 地:中国大陆
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T27471GSK299115AGSK299115A
GSK299115A is a selective ROCK1 Inhibitor. GSK299115A exhibits IC50 of 8nM, 620nM, 560nM for ROCK1, RSK1, p70S6K, respectively.
价 格:¥电议型 号:T27471产 地:中国大陆