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产品数:86095
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T7848PT-2385Inhibitor,inhibit,Hypoxia-inducible factors,HIF/HIF Prolyl-Hydroxylase,HIF-PH,PT 2385,HIFs,PT
PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).
价 格:¥电议型 号:T7848产 地:中国大陆
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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T7596FirocoxibLPS,COX-2,fever,ML1785713,Cyclooxygenase,COX,inhibit,Firocoxib,Inhibitor,anti-inflammatory,
Firocoxib is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
价 格:¥电议型 号:T7596产 地:中国大陆
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T9240sulfopinneuroblastoma,antiproliferative,PIN1-3,tumors,cancer,pancreatic,Inhibitor,sulfopin,inhibit,c
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
价 格:¥电议型 号:T9240产 地:中国大陆
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T7838Losartan CarboxaldehydeDuP 167,EXP-3179,DuP-167,Inhibitor,COX,AT1-R–blocking,intermediate aldehyde m
Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.
价 格:¥电议型 号:T7838产 地:中国大陆
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T7758Thalidomide-O-amido-PEG3-C2-NH2 TFAE3 Ligase Ligand-Linker Conjugates,Cereblon Ligand-Linker Conjuga
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
价 格:¥电议型 号:T7758产 地:中国大陆
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TN1637EurycomalactoneDNA double-strand,Eurycomalactone,NF-κB,protein synthesis,Inhibitor,Nuclear factor-ka
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα/β and IκBα.
价 格:¥电议型 号:TN1637产 地:中国大陆
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T9146ms48107Inhibitor,GPR68,GPCR,MS 48107,ms48107,brain-penetrant,BBB,inhibit,5-HT2B,MS-48107,bioavailabl
MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). It is selective for GPR68 over the closely related proton GPCRs, neurotransmitter transporters, and hERG ion channels. It can readily cross the blood-brain barrier (BBB) in mice.
价 格:¥电议型 号:T9146产 地:中国大陆
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T9121AG-636inhibit,oral,AG 636,AG-636,reversible,DHODH,anticancer,AG636,Inhibitor,Dihydroorotate Dehydrog
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
价 格:¥电议型 号:T9121产 地:中国大陆
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T8930CID44216842diseases,neutrophils,ovarian,disorders,Cdc42,fibroblasts,breast,hepatitis C,CID 44216842,
CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
价 格:¥电议型 号:T8930产 地:中国大陆
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T9627PHD-1-IN-1pocket,ion,Arg367-out,HIF-PH,Hypoxia-inducible factors,site,active,PHD 1 IN 1,orally,Inhib
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).
价 格:¥电议型 号:T9627产 地:中国大陆
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TP1015NFAT Inhibitorinhibit,NFAT Inhibitor 1,dephosphorylation,cell-permeable,NFAT-Luc,NFAT Inhibitor-1,In
NFAT inhibitor is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.
价 格:¥电议型 号:TP1015产 地:中国大陆
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T9030SU4984inhibit,growth,Fibroblast growth factor receptor,Insulin Receptor,fibroblast,insulin,SU4984,SU
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
价 格:¥电议型 号:T9030产 地:中国大陆
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T9295BLU-263BLU 263,BLU263
BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.
价 格:¥电议型 号:T9295产 地:中国大陆
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T12504(+)-KCC2 blocker 1(+)-KCC-2 blocker 1,(+)KCC2 blocker 1,(+) KCC2 blocker 1
(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).
价 格:¥电议型 号:T12504产 地:中国大陆
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TQ0228DerazantinibARQ 087,Derazantinib,Fibroblast growth factor receptor,inhibit,FGFR,ARQ087,Inhibitor
Derazantinib (ARQ-087) is an ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocytes (IC50s: 4.5 nM/1.8 nM/4.5 nM).
价 格:¥电议型 号:TQ0228产 地:中国大陆
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T91492BActpermeable,primary,inhibit,Eukaryotic Initiation Factor (eIF),2BAct,stress,defects,response,fibr
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
价 格:¥电议型 号:T9149产 地:中国大陆
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T9045BemotrizinolBemotrizinol,inhibit,atomic oxygen,Tinosorb S,Inhibitor,feasible acceptor
Bemotrizinol is a UVA absorber used as a topical sunscreen.
价 格:¥电议型 号:T9045产 地:中国大陆
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TN2139Regaloside Blongiflorum,COX,Inhibitor,phenylpropanoid,iNOS,Lilium,Cyclooxygenase,COX-2,anti-inflamma
Regaloside B can inhibit the expression of iNOS and COX-2. Regaloside B is a phenylpropanoid isolated from Lilium longiflorum.It has anti-inflammatory activity.
价 格:¥电议型 号:TN2139产 地:中国大陆
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T60093CHEMBL1380345
CHEMBL1380345 exhibits antibacterial activity against Staphylococcus aureus, Bacillus cereus, and Escherichia coli with pMIC values of 3.64, 3.56, and 3.70, respectively.
价 格:¥电议型 号:T60093产 地:中国大陆