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T118066CDK9 inhibitor HH1
CDK9 inhibitor HH1 is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.
价 格:¥电议型 号:T118066产 地:中国大陆
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T9615CK7Inhibitor,Nek1,CDK,CK-7,Cdk9,CK 7,kidney development,CK7,inhibit,Cyclin dependent kinase,Cdk2
CK7, a?Cdk2/9?inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367.
价 格:¥电议型 号:T9615产 地:中国大陆
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T9446KB-0742 dihydrochlorideKB0742,inhibit,CDK,CDK9,KB-0742,KB 0742,Ser7,Ser2,CRPC,KB 0742 dihydrochlorid
KB-0742 dihydrochloride is a potent, selective and orally inhibitor of ?CDK9.
价 格:¥电议型 号:T9446产 地:中国大陆
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T10745CDK9-IN-7CDK-9-IN-7,CDK9IN7,CDK9 IN 7
CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM).
价 格:¥电议型 号:T10745产 地:中国大陆
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T10746CDK9-IN-8CDK-9-IN-8,CDK9IN8,CDK9 IN 8
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).
价 格:¥电议型 号:T10746产 地:中国大陆
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T10742CDK9-IN-10CDK9IN10,CDK9 IN 10,CDK-9-IN-10
CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.
价 格:¥电议型 号:T10742产 地:中国大陆
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T10741CDK9-IN-1CDK9-IN-1
CDK9-IN-1 is a novel, selective CDK9 inhibitor for the treatment of HIV infection (IC50: 39 nM for CDK9/CycT1).
价 格:¥电议型 号:T10741产 地:美洲
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T10745CDK9-IN-7CDK9-IN-7
CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM).
价 格:¥电议型 号:T10745产 地:美洲
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T10746CDK9-IN-8CDK9-IN-8
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).
价 格:¥电议型 号:T10746产 地:美洲
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T82758CDK9-Cyclin T1 PPI-IN-1;化合物 CDK9-Cyclin T1 PPI-IN-1CDK9-Cyclin T1 PPI-IN-1
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction (PPI), suppressing cell proliferation in TNBC MDA-MB-231 cells with an IC50 of 0.044 μM and inducing apoptosis. This compound diminishes CDK9 transcriptional activity and downregulates phosphorylation of RNA Pol II CTD ser2. In vivo, CDK9-Cyclin T1 PPI-IN-1 effectively impedes tumor growth in a TNBC 4T1 mouse model [1].
价 格:¥电议型 号:T82758产 地:中国大陆
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T82757CDK9-IN-29;化合物 CDK9-IN-29CDK9-IN-29
CDK9-IN-29 (compound Z11) is a potent inhibitor of CDK9, exhibiting high kinase selectivity and an IC50 value of 3.20 nM. It effectively hinders cell proliferation and induces apoptosis [1].
价 格:¥电议型 号:T82757产 地:中国大陆
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T79904PROTAC CDK9/CycT1 Degrader-2;化合物 PROTAC CDK9/CycT1 Degrader-2PROTAC CDK9/CycT1 Degrader-2
PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1].
价 格:¥电议型 号:T79904产 地:中国大陆
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T79704CDK9-IN-28;化合物 CDK9-IN-28CDK9-IN-28
PROTAC CDK9/CycT1 Degrader-1 (compounds 10), a potent CDK9 inhibitor, serves as a target protein ligand for PROTAC synthesis. Exhibiting substantial anti-proliferative activity in solid tumors [1], this compound is instrumental in the targeted degradation of CDK9/CycT1.
价 格:¥电议型 号:T79704产 地:中国大陆
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T79631CDK9-IN-26;化合物 CDK9-IN-26CDK9-IN-26
CDK9-IN-26, also known as compound 1, is a potent inhibitor of Cyclin-Dependent Kinase 9 (CDK9) with an IC50 value of 0.18 μM.[1]
价 格:¥电议型 号:T79631产 地:中国大陆
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T79630CDK9-IN-25;化合物 CDK9-IN-25CDK9-IN-25
CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM. It also exhibits affinity for the main protease of COVID-19 and demonstrates antiviral activity against human coronavirus 229E, with an IC50 of 63.28 μM [1].
价 格:¥电议型 号:T79630产 地:中国大陆
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T79367CDK9-IN-27;化合物 CDK9-IN-27CDK9-IN-27
CDK9-IN-27 (Compound 6a), a CDK9 inhibitor with an IC50 of 0.424 μM, induces apoptosis and S-phase cell cycle arrest. It exhibits cytotoxicity against HepG2, HCT-116, and MCF-7 cell lines, with IC50 values ranging from 10.31 to 40.34 μM, rendering it applicable in cancer research [1].
价 格:¥电议型 号:T79367产 地:中国大陆
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T79354CDK9-IN-24;化合物 CDK9-IN-24CDK9-IN-24
CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced inhibitory impact on tumor proliferation. It impedes cell growth and triggers apoptosis via the downregulation of Mcl-1 and c-Myc, rendering it valuable in the study of acute myeloid leukemia [1].
价 格:¥电议型 号:T79354产 地:中国大陆
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T79037CDK9-IN-23;化合物 CDK9-IN-23CDK9-IN-23
CDK9-IN-23 (Example 4) is a potent inhibitor of CDK9, exhibiting an IC50 value of less than 20 nM [1].
价 格:¥电议型 号:T79037产 地:中国大陆
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T78928PROTAC CDK9 degrader-8;化合物 PROTAC CDK9 degrader-8PROTAC CDK9 degrader-8
PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].
价 格:¥电议型 号:T78928产 地:中国大陆
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T74853PROTAC CDK9 degrader-7;化合物 PROTAC CDK9 degrader-7PROTAC CDK9 degrader-7
PROTAC CDK9 degrader-7 is a proteolysis-targeting chimera (PROTAC) specifically designed to target and mediate the degradation of Cyclin-Dependent Kinase 9 (CDK9) through the proteasome pathway [1].
价 格:¥电议型 号:T74853产 地:中国大陆