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  • T9849HQ461cyclin K degrader,Cyclin dependent kinase,molecular glue,HQ461,HQ 461,HQ-461,CDK12 substrate ph

    HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.

    价 格：￥电议型 号：T9849产 地：中国大陆

  • T64373CDK1-IN-2

    CDK1-IN-2 is a CDK1 inhibitor with IC50 of 5.8 μM. A broad-spectrum kinase profiling of CDK1-IN-2 revealed nonselective inhibition of several kinases.

    价 格：￥电议型 号：T64373产 地：中国大陆

  • T39752CDK12-IN-2

    CDK12-IN-2 is an effective and selective inhibitor of CDK12 with an IC50 of 52 nM, >100 μM, >10 μM and 16 μM for CDK12, CDK2, CDK7, and CDK9. CDK12-IN-2 can be used in studies about the function of CDK12.

    价 格：￥电议型 号：T39752产 地：中国大陆

  • T9758dCeMM3?degradation,dCeMM 3,dCeMM3?,Inhibitor,inhibit,CDK,CDK12,Cyclin dependent kinase,glue degrader

    dCeMM3 is a glue degrader. dCeMM3 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, result in inducing ubiquitination and degradation of cyclin K.

    价 格：￥电议型 号：T9758产 地：中国大陆

  • T4046BX517BX 517；BX-517；PDK1 inhibitor 2

    BX-517 is a potent and selective inhibitor of PDK1.

    价 格：￥电议型 号：T4046产 地：中国大陆

  • T12398MP7PDK1 inhibitor；PDK1 抑制剂

    MP7 is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1).

    价 格：￥电议型 号：T12398产 地：中国大陆

  • T12398MP7MP7,PDK1 inhibitor,

    MP7 is a inhibitor of phosphoinositide-dependent kinase-1 (PDK1).

    价 格：￥电议型 号：T12398产 地：美洲

  • T74998LmNADK1-IN-1；化合物 LmNADK1-IN-1LmNADK1-IN-1

    LmNADK1-IN-1 (compound MC1) is an inhibitor of nicotinamide adenine dinucleotide kinases ( NADK1 ) from L. monocytogenes with a K i value of 54 nM. LmNADK1-IN-1 can be used for the research of bacterial infection [1] .

    价 格：￥电议型 号：T74998产 地：中国大陆

  • T74814PKM2/PDK1-IN-1；化合物 PKM2/PDK1-IN-1PKM2/PDK1-IN-1

    PKM2/PDK1-IN-1, a shikonin thioether derivative, serves as a dual inhibitor for PKM2/PDK1. This compound effectively inhibits the proliferation and induces apoptosis in NSCLC cells. It promotes intercellular ROS production and modulates apoptotic proteins, engaging in both mitochondrial and death receptor pathways [1].

    价 格：￥电议型 号：T74814产 地：中国大陆

  • T64373CDK1-IN-2；化合物CDK1-IN-2cdk1 inhibitor 2；cdk1 inhibitor 2

    CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM. A broad-spectrum kinase profiling of CDK1-IN-2 revealed nonselective inhibition of several kinases.

    价 格：￥电议型 号：T64373产 地：中国大陆

  • T64284PROTAC CDK12/13 Degrader-1；化合物 PROTAC CDK12/13 Degrader-1PROTAC CDK12/13 Degrader-1

    PROTAC CDK12/13 Degrader-1 (7f) is a potent and selective dual degrader of the cell cycle protein-dependent kinases CDK12 (DC50: 2.2 nM) and CDK13 (DC50: 2.1 nM). Breast cancer.

    价 格：￥电议型 号：T64284产 地：中国大陆

  • T63933CDK1-IN-3；化合物 CDK1-IN-3CDK1-IN-3

    CDK1-IN-3 (8g) is a selective CDK1 inhibitor that acts on CDK1 (IC50: 36.8 nM), CDK2 (IC50: 305.17 nM) and CDK5 (IC50: 369.37 nM). CDK1-IN-3 can affect the cell cycle and thus inhibit the growth of cancer cells and can be used in cancer research.

    价 格：￥电议型 号：T63933产 地：中国大陆

  • T63437CDK1-IN-5；化合物 CDK1-IN-5CDK1-IN-5

    CDK1-IN-5 (10h) is a selective CDK1 inhibitor that acts on CDK1 (IC50: 42.19 nM), CDK2 (IC50: 188.71 nM) and CDK5 (IC50: 354.15 nM). CDK1-IN-5 affects the cell cycle and inhibits cancer cell growth and can be used in cancer research.

    价 格：￥电议型 号：T63437产 地：中国大陆

  • T63080CDK1-IN-4；化合物 CDK1-IN-4CDK1-IN-4

    CDK1-IN-4 (10d) is a selective CDK1 inhibitor that acts on CDK1 (IC50: 44.52 nM), CDK2 (IC50: 624.93 nM) and CDK5 (IC50: 135.22 nM). CDK1-IN-4 affects the cell cycle and thus exhibits inhibitory effects on the growth of cancer cells. CDK1-IN-4 can be used in cancer research.

    价 格：￥电议型 号：T63080产 地：中国大陆

  • T62970CDK1-IN-1；化合物 CDK1-IN-1CDK1-IN-1

    CDK1-IN-7 is a potent inhibitor of CDK1 with an IC50 value of 161.2 nM for CDK1/CycB. CDK1-IN-7 induces apoptosis in a p53-dependent manner via the apoptosis-intrinsic pathway. CDK1-IN-7 selectively acts on tumour tissue and has potential anti-proliferative effects. CDK1-IN-7 is a potential CDK1-IN-7 is a potential targeted anti-tumour agent.

    价 格：￥电议型 号：T62970产 地：中国大陆

  • T62405KDM1/CDK1-IN-1；化合物 KDM1/CDK1-IN-1KDM1/CDK1-IN-1

    KDM1/CDK1-IN-1 (compound 4) is a potent inhibitor of KDM1 (IC50: 0.096 μM) and CDK1 (IC50: 0.078 μM). kDM1/CDK1-IN-1 blocks the cell cycle of HOP-92 cells in G2/M phase and induces apoptosis. KDM1/CDK1-IN-1 is highly cytotoxic to CCRF-CEM cells (IC50: 16.34 μM), HOP-92 cells (IC50: 3.45 μM) and Hep-G2 cells (IC50: 7.79 μM).

    价 格：￥电议型 号：T62405产 地：中国大陆

  • T61254CDK1/Cyc B-IN-1；化合物 CDK1/Cyc B-IN-1CDK1/Cyc B-IN-1

    CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].

    价 格：￥电议型 号：T61254产 地：中国大陆

  • T60674DK1；化合物 DK1DK1

    DK1 is a potent estrogen related receptor modulator. DK1 impacts the activity of ERRα receptor and reduces blood glucose. DK1 shows the potential in the diabetes research [1].

    价 格：￥电议型 号：T60674产 地：中国大陆

  • T60583CDK1/2/4-IN-1；化合物 CDK1/2/4-IN-1CDK1/2/4-IN-1

    CDK1/2/4-IN-1 (compound 3a) is a potent inhibitor of CDK with IC 50 values of 1.47, 0.78 and 0.87 μM for CDK1, CDK2 and CDK4, respectively. CDK1/2/4-IN-1 can be used in cancer research. CDK1/2/4-IN-1 arrests cell cycle at G2/M phase and induces apoptosis. CDK1/2/4-IN-1 elevates the level of Bax, caspase-3, and P53 and decreases the level of Bcl-2 [1].

    价 格：￥电议型 号：T60583产 地：中国大陆

  • T4198T.cruzi-IN-1；T.cruzi InhibitorMDK1088|||T.cruzi Inhibitor；MDK1088|||T.cruzi Inhibitor

    T.cruzi-IN-1 (MDK1088) is a Trypanosoma cruzi inhibitor.

    价 格：￥电议型 号：T4198产 地：中国大陆

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