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T8684SotorasibAMG 510,Ras,KRAS,covalent,Sotorasib,regression,mutation,Inhibitor,G12C,anti-tumour,inhibit,
AMG-510 is a selective and orally bioavailable KRAS G12C covalent inhibitor.
价 格:¥电议型 号:T8684产 地:中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格:¥电议型 号:T9303产 地:中国大陆
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T16401Org-12962Org 12962,Org12962
Org-12962 is an effective and selective 5-HT2C?receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A?and 5-HT2B receptors (pEC50s: 6.38 and 6.28, respectively).
价 格:¥电议型 号:T16401产 地:中国大陆
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T62228KRAS G12D inhibitor 14
KRAS G12D inhibitor 14 is an effective inhibitor of KRAS G12D, showing significant antitumor effect and tumor growth inhibition in CT26 tumor models.
价 格:¥电议型 号:T62228产 地:中国大陆
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T6555K-Ras(G12C) inhibitor 12Apoptosis,K-Ras(G-12C) inhibitor 12,inhibit,Inhibitor,Ras,KRas(G12C) inhibit
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
价 格:¥电议型 号:T6555产 地:中国大陆
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T6711Tyrphostin AG1296Fms like tyrosine kinase 3,PDGF,Apoptosis,CD117,inhibit,platelet-derived,CD135,SCFR
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.
价 格:¥电议型 号:T6711产 地:中国大陆
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T6556K-Ras(G12C) inhibitor 9K-Ras(G-12C) inhibitor 9,KRas(G12C) inhibitor 9,Ras,Inhibitor,K-Ras(G12C) inh
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
价 格:¥电议型 号:T6556产 地:中国大陆
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T4092AG126AG 126;Tyrphostin AG126
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vivo, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflam
价 格:¥电议型 号:T4092产 地:中国大陆
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T3725K-Ras(G12C) Inhibitor 6
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
价 格:¥电议型 号:T3725产 地:中国大陆
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T24030Entacapone acidAG 1290;AG1290;AG-1290;恩他卡朋酸
Entacapone is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).
价 格:¥电议型 号:T24030产 地:中国大陆
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T18566Propargyl-PEG12-bromide
Propargyl-PEG12-bromide is a PEG-based PROTAC linker used to synthesize PROTACs.
价 格:¥电议型 号:T18566产 地:中国大陆
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T18143m-PEG12-OHDodecaethylene Glycol Monomethyl Ether
m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T18143产 地:中国大陆
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T18132m-PEG12-acid十一乙二醇单甲醚丙酸
m-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T18132产 地:中国大陆
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T18035Hydroxy-PEG12-BocHydroxy-PEG12-T-Butyl Ester
Hydroxy-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T18035产 地:中国大陆
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T17978Fmoc-PEG12-NHS ester
Fmoc-PEG12-NHS ester is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1].
价 格:¥电议型 号:T17978产 地:中国大陆
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T17955Fmoc-NH-PEG12-CH2CH2COOH(FMOC-氨基)-PEG12-C2-羧酸
Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T17955产 地:中国大陆
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T17719Cbz-NH-PEG12-C2-acid
Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTAC[1].
价 格:¥电议型 号:T17719产 地:中国大陆
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T17668Boc-NH-PEG12-NH2叔丁氧羰基十二聚乙二醇氨基;NHBoc-PEG12-amine
Boc-NH-PEG12-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T17668产 地:中国大陆
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T17667Boc-NH-PEG12-CH2CH2COOH叔丁氧羰基十二聚乙二醇羧乙基
Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T17667产 地:中国大陆
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T17561Biotin-PEG12-NHS ester生物素十二聚乙二醇琥珀酰亚胺酯
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
价 格:¥电议型 号:T17561产 地:中国大陆