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T61016EMI1
EMI1 is an inhibitor of EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI1 has research value in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC).
价 格:¥电议型 号:T61016产 地:中国大陆
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T9753LEI110HepG2 cells,inhibit,thiol hydrolases,LEI110,Inhibitor,LEI-110,lipolysis,Phospholipase,LEI 110
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).
价 格:¥电议型 号:T9753产 地:中国大陆
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T8955PCNA-I1PCNA-I1,PCNA-I-1,DNA/RNA Synthesis,inhibit,PCNAI1,Inhibitor,PCNA I1
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.
价 格:¥电议型 号:T8955产 地:中国大陆
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T6347Ki16198lung,Ki 16198,inhibit,Inhibitor,LPL Receptor,BxPC-3,liver metastasis,Ki16198,Ki-16198,Lysopho
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.
价 格:¥电议型 号:T6347产 地:中国大陆
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T6753AI-10-49inhibit,AI 10 49,AI1049,Inhibitor
AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.
价 格:¥电议型 号:T6753产 地:中国大陆
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T9589SI-113SI113,SI 113
SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.
价 格:¥电议型 号:T9589产 地:中国大陆
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T7137I-191I-191,Inhibitor,I191,inhibit,I 191,Protease Activated Receptor (PAR),Thrombin receptors
I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.
价 格:¥电议型 号:T7137产 地:中国大陆
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T9172Simufilam dihydrochlorideInhibitor,PTI-125,Simufilam,inhibit,PTI 125,PTI125,Simufilam dihydrochlorid
Simufilam dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator, which can be used for the research of Alzheimer´s disease. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
价 格:¥电议型 号:T9172产 地:中国大陆
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T6672Sitaxsentan sodiumIPI1040,Inhibitor,IPI-1040,TBC 11251,Sitaxsentan,inhibit,Sitaxsentan sodium,Endoth
Sitaxsentan (sodium) is a highly selective antagonist of endothelin A receptors.
价 格:¥电议型 号:T6672产 地:中国大陆
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T6484EI1Histone Methyltransferase,Inhibitor,inhibit,Apoptosis,EI-1,EI1,KB145943,EI 1,KB 145943
EI1 is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.
价 格:¥电议型 号:T6484产 地:中国大陆
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T6691TAI-1TAI 1,TAI1,inhibit,Inhibitor,Apoptosis,TAI-1
TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.
价 格:¥电议型 号:T6691产 地:中国大陆
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T6889MI-136PPI,MI 136,Apoptosis,inhibit,MI136,Inhibitor,CRPC,castration,cancer,resistant,MI-136,Androgen
MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.
价 格:¥电议型 号:T6889产 地:中国大陆
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T8969API-1TRAIL,API 1,PKB,Akt,Inhibitor,API-1,inhibit,Akt/PKB inhibitor,Protein kinase B,API1,Apoptosis
API-1 is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
价 格:¥电议型 号:T8969产 地:中国大陆
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T9960MCU-i11MCUi11,MCU i11
MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
价 格:¥电议型 号:T9960产 地:中国大陆
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T9594BI-187004BI187004,BI 187004
BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.
价 格:¥电议型 号:T9594产 地:中国大陆
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T7366NGI-1ML 414,inhibit,Inhibitor,NGI 1,ML-414,NGI-1,Virus Protease,NGI1
NGI-1 is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability.
价 格:¥电议型 号:T7366产 地:中国大陆
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T9317TAK-041inhibit,deficits,social,BALB/c,NBI 1065846,NBI1065846,negative,schizophrenia,TAK-041,GPR139,s
TAK-041 is a potent and selective GPR139 agonist.
价 格:¥电议型 号:T9317产 地:中国大陆
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T7155JH-II-127HEK293,JHII127,3T3 cells,Inhibitor,LRRK2-G2019S,Ser935,Leucine-rich repeat kinase 2,LRRK2,p
JH-II-127 is an orally inhibitor of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, G2019S LRRK2 and A2016T LRRK2 (IC50s = 6.6, 2.2, and 47.7 nM, respectively),
价 格:¥电议型 号:T7155产 地:中国大陆
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T64355TDI-10229CompoundTDI10229
TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays (IC50= 195 nM). TDI-10229 exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound.
价 格:¥电议型 号:T64355产 地:中国大陆
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T6941PI-1840cell proliferation,Proteasome,Caspase,proteasome substrates,poly ADP ribose polymerase,inhibi
PI-1840( IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
价 格:¥电议型 号:T6941产 地:中国大陆