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产品数:86101
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已选条件
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T6784BI-78D3BI-78D3,BI-78D-3,inhibit,BI 78D3,Inhibitor,BI78D3,JNK
BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays > 100 fold selectivity over p38α, and have no activity at mTOR and PI-3K.
价 格:¥电议型 号:T6784产 地:中国大陆
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T6S1371Isovitexininhibit,Isovitexin,Nuclear factor-kappaB,Inhibitor,Nuclear factor-κB,NF-κB,JNK
1. Isovitexin exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.
价 格:¥电议型 号:T6S1371产 地:中国大陆
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T9010IMM-H007JNK,Nuclear factor-κB,WS 070117,IMM H007,AP-1,inflammatory,WS070117,inhibit,AMPK,atheroscler
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
价 格:¥电议型 号:T9010产 地:中国大陆
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T9688CC-90001CC90001,kinase,IPF,JNK,c-Jun,idiopathic,JNK1,Inhibitor,N-terminal,inhibit,CC-90001,CC 90001,
CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.
价 格:¥电议型 号:T9688产 地:中国大陆
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T6927PamapimodRo-4402257,Autophagy,Inhibitor,IL-6,TNF-α,inhibit,R-1503,IL-1β,p38 MAPK,JNK,Pamapimod,p38β,
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.
价 格:¥电议型 号:T6927产 地:中国大陆
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T7190ActeinJNK,Akt,Actein,Apoptosis,PKB,Autophagy,Inhibitor,inhibit,Protein kinase B
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein´s ability to pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders, it has been shown to inhibit the proliferation of human breast cancer cells, by altering the activity of the ER IP3 receptor and Na,K-ATPase, inducing cal
价 格:¥电议型 号:T7190产 地:中国大陆
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TMA0507TomatidineJNK,Tomatidine,Nuclear factor-κB,inhibit,NF-κB,Autophagy,Nuclear factor-kappaB,Inhibitor,E
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. It activates autophagy either in mammal cells or C elegans.
价 格:¥电议型 号:TMA0507产 地:中国大陆
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T7677JNK Inhibitor VIIIJNK,inhibit,Inhibitor,JNK Inhibitor VIII
JNK Inhibitor VIII is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).
价 格:¥电议型 号:T7677产 地:中国大陆
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TQ0089JuglaninJNK,Juglanin,ROS/JNK,Inhibitor,G2/M,arrest,Apoptosis,Autophagy,phase,inhibit,breast cancer
Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.
价 格:¥电议型 号:TQ0089产 地:中国大陆
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T6758AnisomycinAnisomycin,Bacterial,Inhibitor,JNK,DNA/RNA Synthesis,inhibit,Antibiotic,Apoptosis
Anisomycin is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
价 格:¥电议型 号:T6758产 地:中国大陆
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T8477IQ-3Inhibitor,IL-6,inhibit,TNF-α,IQ-3,JNK,IQ 3,IQ3,IL-1β,IL-1α
IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro.
价 格:¥电议型 号:T8477产 地:中国大陆
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T3598JNK-IN-7JNK inhibitor
JNK-IN-7 is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase.
价 格:¥电议型 号:T3598产 地:中国大陆
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T3109SP600125JNK Inhibitor II;1PMV;Nsc75890;Pyrazolanthrone
SP600125 is a JNK1/2/3 inhibitor (IC50: 40/40/90 nM) and 10-fold higher selectivity than MKK4, 25-fold higher selectivity than MKK3, MKK6, PKCα, and PKB.
价 格:¥电议型 号:T3109产 地:中国大陆
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T2668JNK-IN-8JNK Inhibitor XVI
JNK-IN-8 is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.
价 格:¥电议型 号:T2668产 地:中国大陆
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T2234TCS JNK 5aN-(3-氰基-4,5,6,7-四氢苯并[b]噻吩-2-基)-1-萘甲酰胺;SC-202671;SC202671;SC 202671;N-(3-Cyano-4,5,6,7-tetr
TCS JNK 5a is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).
价 格:¥电议型 号:T2234产 地:中国大陆
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T10937LD-JNKI-1 acetateAM-111 acetate;D-JNKI-1 acetate(1445179-97-4 Free base)
D-JNKI-1 acetate is a highly potent and cell-permeable peptide inhibitor of JNK.
价 格:¥电议型 号:T10937L产 地:中国大陆
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T10937D-JNKI-1D-JNKI-1,AM-111,XG-102
D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.
价 格:¥电议型 号:T10937产 地:美洲
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T2668JNK-IN-8JNK-IN-8,JNK Inhibitor XVI,
JNK-IN-8 is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.
价 格:¥电议型 号:T2668产 地:美洲
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T79754JNK-IN-14;化合物 JNK-IN-14JNK-IN-14
JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, 12.7 nM for JNK2, and 10.5 nM for JNK3. It induces early-stage apoptosis, arrests cell population at the G2/M phase, and moderately inhibits beclin-1 production in K562 leukemia cells, demonstrating greater inhibitory efficacy than SP600125. [1]
价 格:¥电议型 号:T79754产 地:中国大陆
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T79489JNK-1-IN-2;化合物 JNK-1-IN-2JNK-1-IN-2
"JNK-1-IN-2 (Compound c6) is a potent inhibitor of JNK-1 with an IC50 of 33.5 nM, and also exhibits inhibitory effects on JNK-2 and JNK-3 with IC50 values of 112.9 nM and 33.2 nM, respectively. This compound effectively inhibits the phosphorylation of c-Jun and has shown potential in reversing lung impairment, making it relevant for research into pulmonary fibrosis [1]."
价 格:¥电议型 号:T79489产 地:中国大陆