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TP2180LCompstatin control peptide acetateCompstatin control peptide acetate
Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.
价 格:¥电议型 号:TP2180L产 地:中国大陆
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T8487EmpesertibBAY-1161909,Empesertib,Inhibitor,inhibit,Mps1,BAY1161909,Monopolar spindle 1
Empesertib is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
价 格:¥电议型 号:T8487产 地:中国大陆
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TP1304CompstatinComplement System,Inhibitor,Compstatin,inhibit
Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.
价 格:¥电议型 号:TP1304产 地:中国大陆
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T1839Mps1-IN-2
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
价 格:¥电议型 号:T1839产 地:中国大陆
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T16130Mps1-IN-3
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
价 格:¥电议型 号:T16130产 地:中国大陆
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T12764Rp-cAMPS triethylammonium saltRp-cAMPS triethylammonium salt
Rp-cAMPS triethylammonium salt is an analog of cAMP.It acts as a potent, competitive and cell-permeable antagonist of cAMP-induced activation of cAMP-dependent PKA I and II with Kis of 6.05 ?M and 9.75 ?M, respectively.
价 格:¥电议型 号:T12764产 地:美洲
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T13852PSI-7409 tetrasodiumPSI-7409 tetrasodium
PSI-7409 tetrasodium is an active 5´-triphosphate metabolite of sofosbuvir (PSI-7977)(IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively).
价 格:¥电议型 号:T13852产 地:美洲
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T8851I3MT-3;化合物I3MT-3HMPSNE;HMPSNE
I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST.
价 格:¥电议型 号:T8851产 地:中国大陆
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T81824Membrane-Permeable Sequence, MPS;化合物 Membrane-Permeable Sequence, MPSMembrane-Permeable Sequence, MP
Membrane-Permeable Sequence (MPS) is a cell-penetrating peptide (CPP) utilized in the investigation of membrane crossing mechanisms [1].
价 格:¥电议型 号:T81824产 地:中国大陆
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T81751MPS-Gαi2;化合物 MPS-Gαi2MPS-Gαi2
MPS-Gαi2, a membrane-permeable sequence (MPS), facilitates research on cell adhesion [1].
价 格:¥电议型 号:T81751产 地:中国大陆
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T81750MPS-Gαi3;化合物 MPS-Gαi3MPS-Gαi3
MPS-Gαi3, a cell-penetrating peptide, facilitates drug delivery [1].
价 格:¥电议型 号:T81750产 地:中国大陆
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T78965Mps1-IN-6;化合物 Mps1-IN-6Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].
价 格:¥电议型 号:T78965产 地:中国大陆
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T77779Mps1-IN-6 (Compound 9);化合物 Mps1-IN-6 (Compound 9)Mps1-IN-6 (Compound 9)
Mps1-IN-6 (Compound 9) is a highly effective Mps1 inhibitor with an IC50 value of 6.4 nM and exhibits significant anti-proliferation and anti-tumor effects on breast cancer cells.
价 格:¥电议型 号:T77779产 地:中国大陆
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T75775Compstatin TFA;化合物 Compstatin TFACompstatin TFA
Compstatin TFA, a potent inhibitor of the complement system C3 characterized by species specificity, is a 13-residue cyclic peptide. It selectively binds to baboon C3 and demonstrates resistance to proteolytic cleavage in baboon blood (similar to humans), effectively inhibiting the activation of the primate complement system. Notably, Compstatin TFA exhibits IC 50 values of 63 μM and 12 μM for the classical and alternative complement pathways, respectively [1] [2] [3].
价 格:¥电议型 号:T75775产 地:中国大陆
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T73708Sp-cAMPS triethylamine;化合物 Sp-cAMPS triethylamineSp-cAMPS triethylamine
Sp-cAMPS triethylamine, a cAMP analog, serves as a potent activator of cAMP-dependent PKA I and II and acts as a competitive inhibitor of phosphodiesterase (PDE3A) with a K i of 47.6 ?M. Additionally, it binds the PDE10 GAF domain with an EC 50 of 40 μM [1] [2] [3].
价 格:¥电议型 号:T73708产 地:中国大陆
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T73628PSB-12379 disodium;化合物 PSB-12379 disodiumPSB-12379 disodium
PSB-12379 disodium is a nucleotide analogue acting as a potent inhibitor of Ecto-5´-Nucleotidase (CD73), demonstrating inhibitory constants (Ki) of 9.03 nM in rats and 2.21 nM in humans [1] [2].
价 格:¥电议型 号:T73628产 地:中国大陆
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T73308Mps1-IN-5;化合物 Mps1-IN-5Mps1-IN-5
Mps1-IN-5 is a potent, orally active Mps1 inhibitor exhibiting an IC50 of 29 nM, known for triggering apoptosis and G2/M phase cell cycle arrest. This compound demonstrates antiproliferative and anti-tumor effects by inhibiting Mps1 phosphorylation and inducing DNA damage [1].
价 格:¥电议型 号:T73308产 地:中国大陆
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T73229Mps1-IN-4;化合物 Mps1-IN-4Mps1-IN-4
Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.
价 格:¥电议型 号:T73229产 地:中国大陆
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T72591Sp-5,6-DCl-cBIMPS;化合物 Sp-5,6-DCl-cBIMPSSp-5,6-DCl-cBIMPS
Sp-5,6-DCl-cBIMPS is a potent, specific activator of cAMP-dependent protein kinases (cAMP-PK) that enhances insulin release and inhibits U46619-induced activation of Rho, Gq, and G12/G13 in platelets.
价 格:¥电议型 号:T72591产 地:中国大陆
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T70095Mps1-IN-1 dihydrochloride;化合物 Mps1-IN-1 dihydrochlorideMps1-IN-1 dihydrochloride
Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM. It effectively inhibits the activity of Mps1 mitotic kinase and disrupts spindle assembly checkpoint (SAC) function, thereby reducing the viability of both cancerous and ´normal´ cells.
价 格:¥电议型 号:T70095产 地:中国大陆