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  • T61392NLRP3-IN-10

    NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.

    价 格：￥电议型 号：T61392产 地：中国大陆

  • T9352hydrocotarnineE3 ligating enzyme,IL-18,NLRP3,E1/E2/E3 Enzyme,hydrocotarnine,inflammasome activation,

    hydrocotarnine?is an inhibitor of Cbl.

    价 格：￥电议型 号：T9352产 地：中国大陆

  • T8828CP 424174CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (

    CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.

    价 格：￥电议型 号：T8828产 地：中国大陆

  • T3230NLRP3-IN-24-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺；5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide；NLRP3 Inflammas

    It is a NLRP3 Inflammasome Inhibitor I.

    价 格：￥电议型 号：T3230产 地：中国大陆

  • T28178NLRP3-IN-9INF 4E；INF4E；NLRP3IN9；NLRP3 IN 9；INF-4E

    NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

    价 格：￥电议型 号：T28178产 地：中国大陆

  • T81668NLRP3 agonist 1；化合物 NLRP3 agonist 1NLRP3 agonist 1

    NLRP3 agonist 1 (compound 23) serves as a potent, orally active agent that activates Caspase-1 enzyme, leading to the cleavage of proinflammatory cytokines pro-IL-1β and pro-IL-18 into their active forms [1].

    价 格：￥电议型 号：T81668产 地：中国大陆

  • T81667NLRP3 agonist 2；化合物 NLRP3 agonist 2NLRP3 agonist 2

    NLRP3 agonist 2 (compound 22) is an orally active agent that activates Caspase-1 in THP1 cells [1].

    价 格：￥电议型 号：T81667产 地：中国大陆

  • T81666NLRP3-IN-22；化合物 NLRP3-IN-22NLRP3-IN-22

    NLRP3-IN-22 (Compound II-4) is an inhibitor of NLRP3, exhibiting a 67% inhibition rate at a concentration of 10 μM [1].

    价 格：￥电议型 号：T81666产 地：中国大陆

  • T81665NLRP3-IN-23；化合物 NLRP3-IN-23NLRP3-IN-23

    NLRP3-IN-23 (Compound 15C) is an inhibitor that significantly impedes heme-mediated activation of the NLRP3 inflammasome at a concentration of 0.1 μM [1].

    价 格：￥电议型 号：T81665产 地：中国大陆

  • T79733NLRP3-IN-20；化合物 NLRP3-IN-20NLRP3-IN-20

    NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β secretion. It possesses excellent pharmacokinetic properties and has shown significant efficacy in models of non-alcoholic steatohepatitis, fatal septic shock, and colitis [1].

    价 格：￥电议型 号：T79733产 地：中国大陆

  • T79696JT001 sodium；化合物 JT001 sodiumNLRP3-IN-19 sodium；NLRP3-IN-19 sodium

    JT001 (NLRP3-IN-19) sodium is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome, thus curbing cytokine release and averting pyroptosis. It is utilized in research focused on nonalcoholic steatohepatitis and liver fibrosis [1].

    价 格：￥电议型 号：T79696产 地：中国大陆

  • T79695NLRP3-IN-19；化合物 NLRP3-IN-19NLRP3-IN-19；NLRP3-IN-19

    JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome. This action results in the suppression of cytokine release and prevention of pyroptosis. JT001 is utilized in research on nonalcoholic steatohepatitis and liver fibrosis [1].

    价 格：￥电议型 号：T79695产 地：中国大陆

  • T78894NLRP3-IN-21；化合物 NLRP3-IN-21NLRP3-IN-21

    NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties. It suppresses the activation of the NLRP3 inflammasome and pyroptosis by inhibiting gasdermin D cleavage, ASC oligomerization, and the assembly of the NLRP3 inflammasome [1].

    价 格：￥电议型 号：T78894产 地：中国大陆

  • T78180NLRP3-IN-18；化合物 NLRP3-IN-18NLRP3-IN-18

    NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 ?M [1].

    价 格：￥电议型 号：T78180产 地：中国大陆

  • T78168NLRP3-IN-17；化合物 NLRP3-IN-17NLRP3-IN-17

    NLRP3-IN-17 is a potent, selective, and orally active inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 7 nM. It effectively inhibits NLRP3-dependent IL-1β secretion in mice, making it a valuable compound for research into chronic inflammatory diseases [1].

    价 格：￥电议型 号：T78168产 地：中国大陆

  • T73034NLRP3-IN-12；化合物 NLRP3-IN-12NLRP3-IN-12

    NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome, effectively reducing IL-1β release by targeting the NLRP3 protein, and demonstrating an IC50 of 0.45 μM. This compound is utilized in the research of inflammatory bowel disease.

    价 格：￥电议型 号：T73034产 地：中国大陆

  • T73018NLRP3-IN-13；化合物 NLRP3-IN-13NLRP3-IN-13

    NLRP3-IN-13 is a selective and potent inhibitor of NLRP3 (IC 50: 2.1 μM), capable of inhibiting both NLRP3 and NLRC4 inflammasomes as well as NLRP3-mediated IL-1β production. Furthermore, NLRP3-IN-13 suppresses NLRP3 ATPase activity. This compound is utilized in research focused on neuroinflammatory disorders.

    价 格：￥电议型 号：T73018产 地：中国大陆

  • T73015NLRP3-IN-16；化合物 NLRP3-IN-16NLRP3-IN-16

    NLRP3-IN-16 is a potent, selective inhibitor of the NLRP3 inflammasome, effectively reducing IL-1β release with an IC50 of 0.065 μM, and is primarily utilized in inflammation research [1].

    价 格：￥电议型 号：T73015产 地：中国大陆

  • T73014NLRP3-IN-15；化合物 NLRP3-IN-15NLRP3-IN-15

    NLRP3-IN-15 is a potent, selective inhibitor of the NLRP3 inflammasome, demonstrating efficacy by inhibiting IL-1β (interleukin-1 beta) release with an IC50 value of 0.114 μM. This compound is utilized in the research of inflammation.

    价 格：￥电议型 号：T73014产 地：中国大陆

  • T73013NLRP3-IN-14；化合物 NLRP3-IN-14NLRP3-IN-14

    NLRP3-IN-14 is a potent, selective inhibitor of the NLRP3 inflammasome, displaying a dissociation constant (K D) of 5.87 μM and an IC50 of 0.131 μM for inhibiting IL-1β release. It is applicable for inflammation research.

    价 格：￥电议型 号：T73013产 地：中国大陆

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