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T8970ML162p62,Glutathione Peroxidase,GPX4,ML-162,Nrf2,anticancer,HRAS,Ferroptosis,Inhibitor,inhibit,ML 16
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)
价 格：￥电议型 号：T8970产 地：中国大陆
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T6S0232EriodictyolEriodictyol,Inhibitor,DNA/RNA Synthesis,inhibit,Keap1-Nrf2,Influenza Virus,Endogenous Met
1. Eriodictyol is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3. Eriodictyol may be a potential therapeutic resource for Atopic dermatitis and an adjunctive agent to control itchiness inAtopic dermatitis.
价 格：￥电议型 号：T6S0232产 地：中国大陆
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TQ0207SulforaphaneInhibitor,Keap1-Nrf2,Apoptosis,Sulforaphane,Histone deacetylases,inhibit,HDAC
Sulforaphane is derived from the consumption of cruciferous vegetables, such as broccoli. It has shown anticancer and cardioprotective activities.
价 格：￥电议型 号：TQ0207产 地：中国大陆
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TN1621Eriodictyol-7-O-glucosideEriodictyol7Oglucoside,radical,flavonoid,Nrf2,scavenger,cisplatin,Keap1-Nrf
Eriodictyol-7-O-glucoside is an Nrf2 activator conferring protection against Cisplatin-induced toxicity. Eriodictyol-7-O-glucoside is a flavonoid and a free radical scavenger with antioxidant activity in pistachio skin.
价 格：￥电议型 号：TN1621产 地：中国大陆
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TN1674Garcinone DKeap1-Nrf2,inhibit,Reactive Oxygen Species,Garcinone D,Inhibitor,STAT
Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM.
价 格：￥电议型 号：TN1674产 地：中国大陆
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T8979AEM1AEM-1,AEM1,inhibit,AEM 1,Inhibitor,Keap1-Nrf2
AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.
价 格：￥电议型 号：T8979产 地：中国大陆
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TQ0211BrusatolNrf2,oxygen,CT-26,NSC172924,NSC-172924,defense,stress,Keap1-Nrf2,Brusatol,chemosensitization
Brusatol is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
价 格：￥电议型 号：TQ0211产 地：中国大陆
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T140424-P-PDOTMelatonin,Melatonin Receptor,GSSG,Nrf2,GSH,4PPDOT,ERK,memory,damage,Inhibitor,oxidative,4 P
4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
价 格：￥电议型 号：T14042产 地：中国大陆
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T6S2356Corynolineinhibit,Corynoline,Inhibitor,Cholinesterase (ChE),Keap1-Nrf2
1. Corynoline is an acetylcholinesterase inhibitor.
价 格：￥电议型 号：T6S2356产 地：中国大陆
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TQ0120CDDO-Iminhibit,Ferroptosis,Keap1-Nrf2,CDDO Im,Inhibitor,CDDO-Im,Peroxisome proliferator-activated re
CDDO-Im is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).
价 格：￥电议型 号：TQ0120产 地：中国大陆
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T6S1302CarnosolRibosomal S6 Kinase (RSK),Keap1-Nrf2,Endogenous Metabolite,S6K,inhibit,Carnosol,Inhibitor
Carnosol has anti-oxidative, anti-inflammatory, antiproliferative and apoptosis inducing properties. Carnosol enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. 3. Carnosol may as a novel agonist of TRPA1 with an EC5 value of 12.46 μM.
价 格：￥电议型 号：T6S1302产 地：中国大陆
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T12253Nrf2-IN-1
Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).
价 格：￥电议型 号：T12253产 地：中国大陆
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T12253Nrf2-IN-1Nrf2-IN-1
Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor.
价 格：￥电议型 号：T12253产 地：美洲
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T81984Keap1-Nrf2-IN-10；化合物 Keap1-Nrf2-IN-10Keap1-Nrf2-IN-10
Keap1-Nrf2-IN-10 (compound 15) is a potent inducer of NQO1 and efficaciously mitigates oxidative stress in gamma-irradiated mice by reducing MDA and ROS levels, as well as NQO1 in the liver, which enhances the survival rate of these mice [1].
价 格：￥电议型 号：T81984产 地：中国大陆
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T80522Keap1-Nrf2 probe；化合物 Keap1-Nrf2 probeKeap1-Nrf2 probe
Keap1-Nrf2 probe [1] is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor erythroid 2-related factor 2 (Nrf2).
价 格：￥电议型 号：T80522产 地：中国大陆
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T80260Keap1-Nrf2-IN-16；化合物 Keap1-Nrf2-IN-16Keap1-Nrf2-IN-16
Keap1-Nrf2-IN-16 is a biologically active peptide with KEAP1 binding activity.
价 格：￥电议型 号：T80260产 地：中国大陆
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T79702Nrf2 activator-9；化合物 Nrf2 activator-9Nrf2 activator-9
Nrf2 activator-9 (compound D-36) is an agent that mitigates oxidative stress by inhibiting the apoptosis of HUVEC cells induced by oxidized low-density lipoprotein (oxLDL) and high glucose (HG). It also protects vascular endothelial cells (VEC) from oxLDL and HG-induced injury, offering potential therapeutic benefits for the prevention and treatment of atherosclerosis [1].
价 格：￥电议型 号：T79702产 地：中国大陆
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T79484Nrf2 activator-8；化合物 Nrf2 activator-8Nrf2 activator-8
Nrf2 Activator-8 (Compound 10e), with an EC50 of 37.9 nM, is a potent Nrf2 activator that demonstrates significant antioxidant and anti-inflammatory properties in BV-2 microglial cells. Furthermore, this compound notably ameliorates spatial memory deficits in a mouse model of lipopolysaccharide (LPS)-induced neuroinflammation [1].
价 格：￥电议型 号：T79484产 地：中国大陆
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T78841Nrf2-IN-3；化合物 Nrf2-IN-3Nrf2-IN-3
Nrf2-IN-3 (Compound R16), a Nrf2 inhibitor, binds to KEAP1 mutants (G333C mKEAP1) thereby restoring the impaired KEAP1/NRF2 interactions. This restoration sensitizes KEAP1-mutant cancer cells to chemotherapeutic agents, such as Cisplatin and Gefitinib, by reestablishing the functionality of the mKEAP1/NRF2 complex [1].
价 格：￥电议型 号：T78841产 地：中国大陆
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T78697Keap1-Nrf2-IN-15；化合物 Keap1-Nrf2-IN-15Keap1-Nrf2-IN-15
Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, displaying IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay [1].
价 格：￥电议型 号：T78697产 地：中国大陆
