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产品数:86101
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已选条件
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T6815HS-1371HS-1371,Inhibitor,Receptor-interacting protein kinases,RIPK,inhibit,HS 1371,RIP kinase,HS1371
HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.
价 格:¥电议型 号:T6815产 地:中国大陆
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T9095Necrostatin-34Necrostatin 34,RIP kinase,FADD,Necrostatin-34,RIPK,inhibit,RIPK1,Receptor-interacting
Necrostatin-34 is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
价 格:¥电议型 号:T9095产 地:中国大陆
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T7397GSK547Inhibitor,RIP kinase,inhibit,GSK-547,GSK547,Receptor-interacting protein kinases,RIPK,GSK 547
GSK547 is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.
价 格:¥电议型 号:T7397产 地:中国大陆
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T9702EclitasertibSAR-443122,RIPK,Receptor-interacting protein kinases,SAR443122,DNL 758,DNL758,Eclitasert
Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 ?Μ).
价 格:¥电议型 号:T9702产 地:中国大陆
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T6852GSK481GSK481,inhibit,Inhibitor,RIPK,GSK-481,RIP kinase,GSK 481,Receptor-interacting protein kinases
GSK481 is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.
价 格:¥电议型 号:T6852产 地:中国大陆
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T9305Necroptosis-IN-1NecroptosisIN1,RIP kinase,Inhibitor,inhibit,Necroptosis,RIPK,Necroptosis IN 1,Recept
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.
价 格:¥电议型 号:T9305产 地:中国大陆
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T9079Apostatin-1Apostatin 1,TRADD,Apostatin-1,Beclin1,RIPK,Autophagy,SH-SY5Y,Receptor-interacting protein
Apostatin-1 is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.
价 格:¥电议型 号:T9079产 地:中国大陆
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T12730RIPK1-IN-4RIPK1IN4,RIPK-1-IN-4,RIPK1 IN 4
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase).
价 格:¥电议型 号:T12730产 地:中国大陆
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T7151GSK2982772inhibit,Receptor-interacting protein kinases,GSK2982772,RIPK,Inhibitor,RIP kinase,GSK 2982
GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.
价 格:¥电议型 号:T7151产 地:中国大陆
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T7795RIPA-56RIPA-56,inhibit,Receptor-interacting protein kinases,RIP kinase,RIPK,Inhibitor,RIPA 56,RIPA56
RIPA-56 is an inhibitor of RIP1
价 格:¥电议型 号:T7795产 地:中国大陆
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T5401GSK2983559 active metaboliteRIPK2 inhibitor 1;RIPK2-IN-1;GSK2983559
GSK 2983559 (RIP2 kinase inhibitor 1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
价 格:¥电议型 号:T5401产 地:中国大陆
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T12731RIPK1-IN-7
RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM),andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.
价 格:¥电议型 号:T12731产 地:中国大陆
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T16755RIPK-IN-4RIPK-IN-4
RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM).
价 格:¥电议型 号:T16755产 地:美洲
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T5401GSK2983559GSK2983559,RIPK2 inhibitor 1,RIPK2-IN-1
GSK 2983559 (RIP2 kinase inhibitor 1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
价 格:¥电议型 号:T5401产 地:美洲
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T81269RIPK1-IN-16;化合物 RIPK1-IN-16RIPK1-IN-16
RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo. It shields mice from TNF-induced systemic inflammatory response syndrome and sepsis [1].
价 格:¥电议型 号:T81269产 地:中国大陆
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T81268RIPK1-IN-17;化合物 RIPK1-IN-17RIPK1-IN-17
RIPK1/3-IN-1 (Compound 10) is a selective inhibitor of both RIPK1 and RIPK3, effectively preventing necroptosis by blocking the phosphorylation of RIPK1, RIPK3, and MLKL [1].
价 格:¥电议型 号:T81268产 地:中国大陆
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T81267RIPK3-IN-4;化合物 RIPK3-IN-4RIPK3-IN-4
RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell damage. It alleviates acute kidney injury by attenuating Cisplatin- and I/R-induced kidney damage, along with associated inflammatory responses and necroptosis [1].
价 格:¥电议型 号:T81267产 地:中国大陆
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T79352RIPK2/3-IN-1;化合物 RIPK2/3-IN-1RIPK2/3-IN-1
RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3. Additionally, in a 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay, RIPK2/3-IN-1 demonstrates an IC50 value of 14 ± 4 nM against RIPK2 [1].
价 格:¥电议型 号:T79352产 地:中国大陆
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T78784RIPK3-IN-3;化合物 RIPK3-IN-3RIPK3-IN-3
RIPK3-IN-3 (compound 20) is a selective RIPK3 inhibitor that demonstrates potent activity with an IC50 value of 10 nM. This compound effectively blocks RIPK3-mediated phosphorylation of MLKL, preventing its oligomerization and subsequent induction of necroptosis. Additionally, RIPK3-IN-3 suppresses CXCL5 secretion and impedes AsPC-1 cell migration and invasion [1].
价 格:¥电议型 号:T78784产 地:中国大陆
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T78597RIPK2-IN-3;化合物 RIPK2-IN-3RIPK2-IN-3
RIPK2-IN-3 (FCG806791773) is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with an IC50 value of 6.39 μM against recombinant truncated RIPK2. It is applicable in the study of inflammation and cancer [1].
价 格:¥电议型 号:T78597产 地:中国大陆