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产品数:86101
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TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
价 格:¥电议型 号:TP1898产 地:中国大陆
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T61518TAK-653
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats.
价 格:¥电议型 号:T61518产 地:中国大陆
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T9031MCU-i4C2C12,Inhibitor,mitochondrial,MCU-i-4,Mitochondrial Metabolism,MCU-i4,MCUi4,Ca2+,uptake,inhibi
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
价 格:¥电议型 号:T9031产 地:中国大陆
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T7200TAK-960Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,in
TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.
价 格:¥电议型 号:T7200产 地:中国大陆
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TL0006Cichoric Acidp-Akt,inhibit,ROS,anti-inflammatory,Apoptosis,glucose uptake,insulin resistance,glucosa
Chicoric Acid is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and independent.
价 格:¥电议型 号:TL0006产 地:中国大陆
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T8818TC-G 1005TC G 1005,G protein-coupled Bile Acid Receptor 1,levels,coupled,glucose,TCG 1005,Takeda,inh
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.
价 格:¥电议型 号:T8818产 地:中国大陆
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T9699TAK-615LPA1,fibrosis,LPL Receptor,Lysophospholipid Receptor,TAK615,modulator,TAK-615,NAM,inhibit,pul
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.
价 格:¥电议型 号:T9699产 地:中国大陆
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T5043Lentinanresponse,β-glucan,Shiitake,gastric,inhibit,cancer,Lentinan,modifier,Inhibitor,biological,mus
Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.
价 格:¥电议型 号:T5043产 地:中国大陆
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T6461Dapoxetine hydrochlorideBenign,BPH,serotonin reuptake,SERT,sexual disorder,LY210448,SLC6A4,Dapoxetin
Dapoxetine HCl is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
价 格:¥电议型 号:T6461产 地:中国大陆
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T8151MobocertinibAP-32788,Epidermal growth factor receptor,TAK-788,H1975,Inhibitor,Mobocertinib,HCC827,in
Mobocertinib is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent
价 格:¥电议型 号:T8151产 地:中国大陆
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T6493Escitalopram OxalateEscitalopram Oxalate,reuptake,impairments,selectivity,antidepressant,inhibit,SLC
Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
价 格:¥电议型 号:T6493产 地:中国大陆
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TQ0181ResatorvidTAK242,Inhibitor,MyD88,Resatorvid,inhibit,TNF-R,CLI 095,inflammatory,diseases,TNFR,CLI095,
Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM).
价 格:¥电议型 号:TQ0181产 地:中国大陆
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T7499TAK-779TAK-779,TAK 779,CCR,HIV,Human immunodeficiency virus,Takeda779,Takeda-779,TAK779,CXCR,inhibit
TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).
价 格:¥电议型 号:T7499产 地:中国大陆
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TN1839Kumatakeninovarian,Inhibitor,cell,Apoptosis,inhibit,Kumatakenin,cancer
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.
价 格:¥电议型 号:TN1839产 地:中国大陆
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T8388VonoprazanTAK-438,TAK 438,GERD,TAK438,Bacterial,antisecretory,blocker,peptic,Proton Pump,secretion,i
Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
价 格:¥电议型 号:T8388产 地:中国大陆
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T9317TAK-041inhibit,deficits,social,BALB/c,NBI 1065846,NBI1065846,negative,schizophrenia,TAK-041,GPR139,s
TAK-041 is a potent and selective GPR139 agonist.
价 格:¥电议型 号:T9317产 地:中国大陆
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T6039TAK-285EGFR,ErbB-1,HER2,Inhibitor,CNS,penetration,orally,Epidermal growth factor receptor,inhibit,an
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.
价 格:¥电议型 号:T6039产 地:中国大陆
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T6597Mosapride CitrateTAK-370,5-hydroxytryptamine Receptor,AS4370,TAK370,AS 4370,Inhibitor,Mosapride Citr
Mosapride Citrate, a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.
价 格:¥电议型 号:T6597产 地:中国大陆
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TQ0297CenicrivirocCC chemokine receptor,inhibit,HIV,TBR 652,TAK 652,TBR652,Inhibitor,Human immunodeficienc
Cenicriviroc is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and HIV-2, and displays potent anti-infective and anti-inflammatory activity.
价 格:¥电议型 号:TQ0297产 地:中国大陆
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T6692TAK-733inhibit,Inhibitor,TAK-733,MAP2K,MAPKK,MEK,Mitogen-activated protein kinase kinase
MEK Inhibitor TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
价 格:¥电议型 号:T6692产 地:中国大陆