T6767TCS7010Aurora Kinase,inhibit,TCS 7010,Apoptosis,TCS-7010,TCS7010,Inhibitor

Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay. It is 1000-fold more selective for Aurora A than Aurora B.

价 格：￥电议型 号：T6767产 地：中国大陆

T6451Clodronic acid disodium saltClodronic acid disodium,inhibit,ADP,mitochondria,first-generation,metast

Clodronate Disodium, a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.

价 格：￥电议型 号：T6451产 地：中国大陆

TCS0102PulegoneEndogenous Metabolite,Transient receptor potential channels,TRP Channel,Pulegone,Inhibitor,i

1. Pulegone has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect that appears to independ on the opening of L-type calcium channels. 3. Pulegone has negative reinforcing properties and seems to possess anxiolytic-like actions unrelated to the benzodiazepine site of the γ-aminobutyric acid type A (GABAA) receptor.

价 格：￥电议型 号：TCS0102产 地：中国大陆

T6674L-Ascorbic acid sodium saltCa channels,Vitamin C,Reactive Oxygen Species,L Ascorbic acid sodium salt

Sodium Ascorbate is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.

价 格：￥电议型 号：T6674产 地：中国大陆

TCS1188Mogroside IIIinhibit,Mogroside III,Inhibitor

Mogroside III is a triterpenoid glycoside and a nonsugar sweetener. Mogroside III is transformed by human intestinal bacteria to release secondary glycoside mogroside IIA1 and aglycone mogrol.

价 格：￥电议型 号：TCS1188产 地：中国大陆

T8449TC-I2000TCI2000,TC-I-2000,TC I2000

TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.

价 格：￥电议型 号：T8449产 地：中国大陆

TCS1554trans-BenzylideneacetonePhospholipase,gram-negative,Inhibitor,inhibit,entomopathogenic,transBenzylid

trans-4-Phenyl-3-buten-2-one is used in various synthetic preparations.

价 格：￥电议型 号：TCS1554产 地：中国大陆

TWS2045Bruceine DParasite,Notch,Apoptosis,Bruceine D,Inhibitor,inhibit

1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW199 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.

价 格：￥电议型 号：TWS2045产 地：中国大陆

T131725Compound TCFN92660

价 格：￥电议型 号：T131725产 地：中国大陆

T8818TC-G 1005TC G 1005,G protein-coupled Bile Acid Receptor 1,levels,coupled,glucose,TCG 1005,Takeda,inh

TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.

价 格：￥电议型 号：T8818产 地：中国大陆

TP2051LCTCE 9908 acetateCTCE 9908 acetate

CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.

价 格：￥电议型 号：TP2051L产 地：中国大陆

T17006TC-I 2014TCI 2014,TC I 2014

TC-I 2014 shows antiallodynic properties in pain models. TC-I 2014 is a potent and orally active Benzimidazole-containing transient receptor potential melastatin 8 antagonist (IC50: 0.8 nM, 3.0 nM, and 4.4 nM for canine, human and rat channels respectively).

价 格：￥电议型 号：T17006产 地：中国大陆

TP1216CaM kinase II inhibitor TFA saltCaM kinase II inhibitor TFA salt

Autocamtide-2-Related Inhibitory Peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.

价 格：￥电议型 号：TP1216产 地：中国大陆

TCS2070Homogentisic acidHomogentisic acid,inhibit,Endogenous Metabolite,Inhibitor

1. Homogentisic acid shows interesting antioxidant and antiradical activities, and protective effect against thermal-cholesterol degradation, comparable to those of well known antioxidants. 2. Homogentisic acid is the primary precursor of melanin synthesis in Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana. 3. A derivative of homogentisic acid which inhibits Pfnek-1 with an IC(5) around 1.8 muM, this product is moderately active in vitro against a FcB1 P. falciparum strain (IC(5

价 格：￥电议型 号：TCS2070产 地：中国大陆

TQ0082AticaprantCERC 501,inhibit,LY2456302,Opioid Receptor,Aticaprant,Inhibitor,CERC501,LY 2456302

Aticaprant (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).

价 格：￥电议型 号：TQ0082产 地：中国大陆

T13867RH01386RH 01386,βTC6 cells,RH01386,RH-01386,inhibit,Apoptosis,Inhibitor,type 2 diabetes,β cell

RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.

价 格：￥电议型 号：T13867产 地：中国大陆

TCS1704Artemitininhibit,Artemitin,Inhibitor

1. Artemetin has anti-inflammatory activity. 2. Artemetin protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. 3. Intravenous injection of Artemetin (.75 mg/kg) significantly reduces the hypertensive response to angiotensin I while increases the average length of bradykinin-induced hypotension.

价 格：￥电议型 号：TCS1704产 地：中国大陆

T23439TC-N 1752TCN 1752,TC N 1752

TC-N 1752 is an orally active inhibitor of Nav1.7 channel with IC50 of 0.17 μM. TC-N 1752 shows analgesic activities.

价 格：￥电议型 号：T23439产 地：中国大陆

T23445Anxiolytic/nonsedative agent-1

Anxiolytic/nonsedative agent-1 is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.

价 格：￥电议型 号：T23445产 地：中国大陆

TCS1772Dehydroabietic acidinhibit,Dehydroabietic acid,Inhibitor

1. Dehydroabietic acid (DAA) is an EBV-EA activation inhibitor. 2. DAA is a useful food-derived compound for treating obesity-related diseases, by decreasing plasma glucose, insulin levels, plasma triglyceride (TG) , and hepatic TG levels. 3. DAA derivatives displays anti-secretory and anti-pepsin effect in animal models.

价 格：￥电议型 号：TCS1772产 地：中国大陆