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T60072ZL0590non-KAc binding site,ZL0590,ZL-0590,BRD4 BD1,Inhibitor,acute airway inflammation,inhibit,Epige
ZL0590 is an effective and selective inhibitor of BD1-BRD4 (IC50 = 90 nM) with anti-inflammatory activities.
价 格：￥电议型 号：T60072产 地：中国大陆
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TP1263Fz7-21lipid-binding groove,FZD7,Wnt,Fz7 21,Wnt–β-catenin,Fz-7-21,conformation,FZD7 CRD,intestinal or
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
价 格：￥电议型 号：TP1263产 地：中国大陆
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T9109SSAA09E2domain,SARS-CoV,receptor,SSAA09E2,inhibit,SARS coronavirus,Inhibitor,spike,ACE2,binding,SSAA
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).
价 格：￥电议型 号：T9109产 地：中国大陆
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T6569Mimosineanti-fibrosis,Fe(III),Anti-cancer,herbicida,inhibit,Apoptosis,iron-binding,insecticidal,Mimo
L-Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.
价 格：￥电议型 号：T6569产 地：中国大陆
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T8553BC-1471IL-1β,Inhibitor,STAM-binding protein,inhibit,BC-1471,BC1471,DUBs,STAMBP,NALP7,BC 1471,Deubiqu
BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits inflammasome activity of NALP7 (NACHT, LRR and PYD domains-containing protein 7) [1].
价 格：￥电议型 号：T8553产 地：中国大陆
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T7904SR 19881SR-19881,estrogen-related receptor,nuclear receptor,amide,SR19881,phenol,ligand binding doma
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).
价 格：￥电议型 号：T7904产 地：中国大陆
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T8719SC99orally,ERK,c-Src,SC 99,ATP-binding,phosphorylation,platelet,AKT,Janus kinase,activation,anti-mye
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities
价 格：￥电议型 号：T8719产 地：中国大陆
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T6995Ochromycinoneanticancer,Ochromycinone,Bacterial,dimerization,binding,STAT3,Inhibitor,antimicrobial,S
STA-21 is a selective STAT3 inhibitor.
价 格：￥电议型 号：T6995产 地：中国大陆
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TQ0003740 Y-PVSMC,PI3K,inhibit,alzheimer’s disease,aortic,p85 binding,SH2,740 Y-P,Autophagy,740 Y P,cancer
740 Y-P is a potent and cell-permeable activator of PI3K.
价 格：￥电议型 号：TQ0003产 地：中国大陆
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T16766Ro 08-2750growth,MSI,Ro 082750,p75NTR,TRKA,RNA-binding,Nerve,NGF,Inhibitor,leukemia,Apoptosis,AML,Ro
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 ?M. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA.
价 格：￥电议型 号：T16766产 地：中国大陆
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T9108BI-0115inhibit,BI-0115,LOX-1,atherosclerosis,BI0115,BI 0115,oxLDL binding,Inhibitor
BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces are key to the formation of the receptor tetramer thereby blocking oxLDL binding.
价 格：￥电议型 号：T9108产 地：中国大陆
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TP1736LFibrinogen-Binding Peptide 137235-80-4(fb-acetate)Fibrinogen Binding Peptide 137235 80 4(fb acetate)
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin
价 格：￥电议型 号：TP1736L产 地：中国大陆
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T8533ML318acyl-binding,pyoverdine,Antibiotic,production,ML318,PAO1,ML-318,Inhibitor,ML 318,iron,P.aerugin
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
价 格：￥电议型 号：T8533产 地：中国大陆
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T12557PROTAC BET-binding moiety 1PROTAC BET-binding moiety 1
PROTAC BET-binding moiety 1 is a key intermediate in the synthesis of high affinity BET inhibitors
价 格：￥电议型 号：T12557产 地：美洲
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T12558PROTAC BET-binding moiety 2PROTAC BET-binding moiety 2
PROTAC BET-binding moiety 2 is an BET bromodomain inhibitor.
价 格：￥电议型 号：T12558产 地：美洲
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T83756S1H TFA；化合物 S1H TFASite 1-binding Helix；Site 1-binding Helix
S1H, a synthetic peptide mimetic of human growth hormone amino acids 36-51, acts as an antagonist to the growth hormone receptor. It forms an α-helical structure in solution and inhibits STAT5 phosphorylation triggered by human growth hormone in SK-MEL-28 and MALME-3M melanoma cell lines, as well as prolactin in IM-9 B cell lymphocytes, at concentrations of 100 and 200 nM.
价 格：￥电议型 号：T83756产 地：中国大陆
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T83742SBP1 TFA；化合物 SBP1 TFASpike Binding Peptide 1；Spike Binding Peptide 1
Spike Binding Peptide 1 (SBP1), representing amino acids 21-43 of angiotensin-converting enzyme 2 (ACE2), has been utilized in a novel approach involving lipid nanoparticles (LNPs) encapsulated with oseltamivir phosphate and conjugated to SBP1. This formulation aims to investigate the possibility of achieving a controlled, long-term in vivo release of oseltamivir phosphate. Furthermore, a 2% concentration of SBP1 immobilized on crosslinked networks composed of hydroxy acrylate and ethylxanthate
价 格：￥电议型 号：T83742产 地：中国大陆
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T83739Myr-Tat-CBD3 TFA；化合物 Myr-Tat-CBD3 TFAMyr-Tat-Calcium Channel-binding Domain 3|||N-myristate-Tat-CBD3
Myr-Tat-CBD3 is a chemical compound that serves as an inhibitor of the protein-protein interaction between the N-type voltage-gated calcium channel Cav2.2 and collapsin response mediator protein 2 (CRMP2). This compound effectively disrupts the Cav2.2-CRMP2 interaction by about 81% at a 10 ?M concentration and demonstrates an inhibitory concentration 50 (IC50) value of approximately 2.8 ?M against potassium-induced calcium influx in primary rat dorsal root ganglion (DRG) neurons. Furthermore, at
价 格：￥电议型 号：T83739产 地：中国大陆
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T83729Tat-CIRP TFA；化合物 Tat-CIRP TFATat-Cold-inducible RNA Binding Protein；Tat-Cold-inducible RNA Binding P
Tat-CIRP, a peptide inhibitor, impedes the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP) by binding to MD-2. This disrupts the MD-2 and CIRP interaction as confirmed in co-immunoprecipitation assays. Notably, in vivo studies reveal that Tat-CIRP, at dosages of 10 and 20 mg/kg, significantly reduces infarct volume in both a mouse model of middle cerebral artery occlusion (MCAO) and a
价 格：￥电议型 号：T83729产 地：中国大陆
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T83193Acetyl-Heme-Binding Protein 1 (1-21) (human)；化合物 Acetyl-Heme-Binding Protein 1 (1-21) (human)Acetyl-
Acetyl-Heme-Binding Protein 1 (1-21) (human) is a short peptide comprising the initial 21 amino acids of the hemopexin Acetyl-Heme-Binding Protein 1, which is involved in heme binding, heme metabolism, and the release of hemoglobin [1].
价 格：￥电议型 号：T83193产 地：中国大陆
