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T12559PROTAC BET degrader-2PROTAC BET degrader-2
PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 of 9.6 nM ).
价 格：￥电议型 号：T12559产 地：美洲
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T8744PROTAC BRAF-V600E degrader-2；化合物 T8744PROTAC BRAF-V600E degrader-2
PROTAC BRAF-V600E degrader-2 is a useful organic compound for research related to life sciences. The catalog number is T8744 and the CAS number is 2417296-82-1.
价 格：￥电议型 号：T8744产 地：中国大陆
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T82253GSPT1 degrader-2；化合物 GSPT1 degrader-2GSPT1 degrader-2
GSPT1 degrader-2 is a potent degrader of GSPT1 [1].
价 格：￥电议型 号：T82253产 地：中国大陆
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T81386PROTAC BRD4 Degrader-22；化合物 PROTAC BRD4 Degrader-22PROTAC BRD4 Degrader-22
PROTAC BRD4 Degrader-22 (Compd 44h) is a PROTAC-based degrader targeting BRD4, exhibiting a pDC50 of 9.2 in MOLT4 cells over 24 hours [1].
价 格：￥电议型 号：T81386产 地：中国大陆
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T81385PROTAC BRD9 Degrader-2；化合物 PROTAC BRD9 Degrader-2PROTAC BRD9 Degrader-2
PROTAC BRD9 Degrader-2 is a bifunctional compound designed for the targeted degradation of BRD9 in cancer research applications.
价 格：￥电议型 号：T81385产 地：中国大陆
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T81376PROTAC SMARCA2 degrader-2；化合物 PROTAC SMARCA2 degrader-2PROTAC SMARCA2 degrader-2
PROTAC SMARCA2 degrader-2, a selective and powerful degrader of SMARCA2/4, exhibits an IC50 of <0.1 μΜ in the HeLa HiBiT assay.this compound holds promise for research into cancers related to or deficient in SMARCA4 [1].
价 格：￥电议型 号：T81376产 地：中国大陆
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T81374PROTAC TTK degrader-2；化合物 PROTAC TTK degrader-2PROTAC TTK degrader-2
PROTAC TTK Degrader-2 is a potent threonine tyrosine kinase (TTK) PROTAC degrader, achieving DC50 values of 3.1 nM in COLO-205 cells and 12.4 nM in HCT-116 cells. It demonstrates effective target degradation and anticancer activity in a COLO-205 human colorectal cancer cell xenograft mouse model [1].
价 格：￥电议型 号：T81374产 地：中国大陆
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T80647Androgen receptor degrader-2；化合物 Androgen receptor degrader-2Androgen receptor degrader-2
Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].
价 格：￥电议型 号：T80647产 地：中国大陆
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T79904PROTAC CDK9/CycT1 Degrader-2；化合物 PROTAC CDK9/CycT1 Degrader-2PROTAC CDK9/CycT1 Degrader-2
PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1].
价 格：￥电议型 号：T79904产 地：中国大陆
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T79818PROTAC BRD4 Degrader-21；化合物 PROTAC BRD4 Degrader-21PROTAC BRD4 Degrader-21
PROTAC BRD4 Degrader-21 (Comp 74), a potent degrader of BRD4, has demonstrated substantial inhibition of tumor growth in mouse xenograft models, showing its potential for use in anticancer research [1].
价 格：￥电议型 号：T79818产 地：中国大陆
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T79742CARM1 degrader-2；化合物 CARM1 degrader-2CARM1 degrader-2
PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associated argininemethyltransferase (CARM1). It not only promotes the degradation of CARM1 but also prevents the methylation of its substrates, including poly(A)-binding protein PABP1 and BGR1-associated factor BAF155, which consequently inhibits breast cancer cell migration [1].
价 格：￥电议型 号：T79742产 地：中国大陆
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T79315PROTAC TG2 degrader-2；化合物 PROTAC TG2 degrader-2PROTAC TG2 degrader-2
PROTAC TG2 degrader-2 (compound 7) is a selective competitive degrader of Transglutaminase 2 (TG2), exhibiting a dissociation constant (Kd) greater than 100 μM. It inhibits cell migration and reduces TG2 levels in ovarian cancer cells, making it a valuable tool for ovarian cancer research [1].
价 格：￥电议型 号：T79315产 地：中国大陆
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T79161PROTAC PTPN2 degrader-2 TFA；化合物 PROTAC PTPN2 degrader-2 TFAPROTAC PTPN2 degrader-2 TFA
PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent degrader of Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2), with potential applications in cancer and metabolic disease research [1].
价 格：￥电议型 号：T79161产 地：中国大陆
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T79160PROTAC PTPN2 degrader-2；化合物 PROTAC PTPN2 degrader-2PROTAC PTPN2 degrader-2
PROTAC PTPN2 degrader-2 (example 187B) is a potent agent capable of degrading PTPN2, which holds potential for research in cancer and metabolic diseases [1].
价 格：￥电议型 号：T79160产 地：中国大陆
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T78983STAT3 degrader-2；化合物 STAT3 degrader-2STAT3 degrader-2
STAT3 Degrader-2 is a PROTAC-based compound that effectively reduces the total STAT3 protein levels, and is utilized in the research of cancer and various diseases [1].
价 格：￥电议型 号：T78983产 地：中国大陆
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T78956PROTAC BRD3/BRD4-L degrader-2；化合物 PROTAC BRD3/BRD4-L degrader-2PROTAC BRD3/BRD4-L degrader-2
PROTAC BRD3/BRD4-L degrader-2, a PROTAC molecule, selectively degrades cellular BRD3 and BRD4-L with K i values of 16.91 and 2.8 nM, respectively, and exhibits robust antitumor activity in mouse xenograft models, serving as a research tool for cancer [1].
价 格：￥电议型 号：T78956产 地：中国大陆
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T75099PROTAC STAT3 degrader-2；化合物 PROTAC STAT3 degrader-2PROTAC STAT3 degrader-2
PROTAC STAT3 degrader-2 is a selective and efficacious PROTAC degrader of STAT3 protein with a DC 50 of 3.54 μM in Molm-16 Cell. PROTAC STAT3 degrader-2 has the potential for cancer research [1] .
价 格：￥电议型 号：T75099产 地：中国大陆
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T75023Nampt degrader-2；化合物 Nampt degrader-2Nampt degrader-2
Nampt degrader-2, a fluorescent PROTAC, exhibits efficient degradation of NAMPT at an IC50 of 41.9 nM. It operates by binding to both NAMPT and VHL, initiating the formation of a ternary complex that triggers NAMPT degradation through the ubiquitin-proteasome system (UPS). This activity significantly lowers NAD+ levels and displays potent antitumor effects [1].
价 格：￥电议型 号：T75023产 地：中国大陆
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T74518PROTAC VEGFR-2 degrader-2；化合物 PROTAC VEGFR-2 degrader-2PROTAC VEGFR-2 degrader-2
PROTAC VEGFR-2 degrader-2 (PROTAC-4), a specific degrader of VEGFR-2, demonstrates minimal inhibition of VEGFR-2 (IC50 > 1 μM) and low anti-proliferative activity towards EA.hy926 cells (IC50 > 100 μM) [1].
价 格：￥电议型 号：T74518产 地：中国大陆
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T74430SHP2 protein degrader-2；化合物 SHP2 protein degrader-2SHP2 protein degrader-2
SHP2 protein degrader-2 (SHP2-D26), a PROTAC degrader targeting the SHP2 protein, effectively diminishes its expression levels across various cancer cell types [1].
价 格：￥电议型 号：T74430产 地：中国大陆
