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T4230PF-3758309 hydrochloride;化合物PF-3758309 hydrochloridePF-03758309 hydrochloride;PF-03758309 hydrochlor
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation
价 格:¥电议型 号:T4230产 地:中国大陆
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T4165Delpazolid;化合物DelpazolidLCB01-0371;LCB01-0371
Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacter
价 格:¥电议型 号:T4165产 地:中国大陆
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T41037Ecamsule disodium;依茨舒二钠Ecamsule disodium
Ecamsule disodium is a versatile UVA filter compound commonly employed in the formulation of sunscreen products. Its primary role is to mitigate the potential harm posed by solar radiation through the prevention of various biological repercussions induced by UV exposure. These include the inhibition of pyrimidine dimer formation, the reduction of p53 protein accumulation, and the downregulation of collagenase 2 expression.
价 格:¥电议型 号:T41037产 地:中国大陆
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T40379Bax BH3 peptide (55-74), wild type;Bax BH3 peptide (55-74), wild typeBax BH3 peptide (55-74), wild t
Bax BH3 peptide (55-74), wild type is a 20-amino acid peptide (Bax 1) known for its ability to induce apoptosis in various cell line models.
价 格:¥电议型 号:T40379产 地:中国大陆
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T40378Fmoc-N-amido-PEG2-alcohol;Fmoc-N-amido-PEG2-alcoholFmoc-N-amido-PEG2-alcohol;Fmoc-N-amido-PEG2-alcoh
Fmoc-N-amido-PEG2-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T40378产 地:中国大陆
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T40377Nicotredole;尼可曲朵Tryptamide;Tryptamide|||尼可曲多;尼可曲朵
Nicotredole (Tryptamide) (Tryptamide) is an orally active analgesic and anti-inflammatory agent. Nicotredole exhibits evident anti-inflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity.
价 格:¥电议型 号:T40377产 地:中国大陆
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T40376L-Phenylalanine-15NL-苯丙氨酸 15NL-苯丙氨酸 15N|||(S)-2-Amino-3-phenylpropionic acid-15N|||L-Phenylalanine-1
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the product
价 格:¥电议型 号:T40376产 地:中国大陆
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T40375TFAX 594,SE;TFAX 594,SETFAX 594,SE
TFAX 594,SE is a red fluorescent dye that maintains its fluorescence properties regardless of the pH level, ranging from 4 to 10. This dye produces highly intense and photostable conjugates when combined with proteins or antibodies, such as goat anti-mouse IgG.
价 格:¥电议型 号:T40375产 地:中国大陆
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T40374Pal-Glu(OSu)-OH;Pal-Glu(OSu)-OHPal-Glu(OSu)-OH
Pal-Glu(OSu)-OH is a side chain specific to Liraglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist employed in type 2 diabetes mellitus research.
价 格:¥电议型 号:T40374产 地:中国大陆
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T40373Ganoderic acid ε;灵芝酸 εGanoderic acid ε
Ganoderic acid ε, a naturally occurring terpenoid, is extracted from the Fungus Ganoderma lucidum. This compound possesses an ED 50 value of 12.2 μg/mL, as demonstrated in its impact on Meth-A tumor cells.
价 格:¥电议型 号:T40373产 地:中国大陆
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T403722,4-Diisopropylphenol;2,4-Diisopropylphenol2,4-Diisopropylphenol
2,4-Diisopropylphenol is a widely accepted chemical agent.
价 格:¥电议型 号:T40372产 地:中国大陆
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T40371Vat Blue 2;Vat Blue 2Vat Blue 2
Vat Blue 2, a indigo derivative, is a dark blue 5,5´-dibromo-4,4´-dichloroindigo dye.
价 格:¥电议型 号:T40371产 地:中国大陆
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T403702′-Deoxyadenosine 5′-monophosphate disodium;2′-脱氧腺苷-5′-单磷酸二钠2′-Deoxyadenosine 5′-monophosphate disod
2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
价 格:¥电议型 号:T40370产 地:中国大陆
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T4037Phorbol;佛波醇4β-Phorbol|||(+)-Phorbol;4β-Phorbol|||佛波醇|||(+)-Phorbol
Phorbol (4β-Phorbol), a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.
价 格:¥电议型 号:T4037产 地:中国大陆
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T40037TimtraxanibTimtraxanibAVI-3207
Timtraxanib (AVI-3207) is a potent and specific inhibitor of VEGF-2, offering great potential for investigating senile macular degeneration.
价 格:¥电议型 号:T40037产 地:中国大陆
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T39037Tiludronate disodium hemihydrate;替鲁膦酸二钠半水合物Tiludronic acid disodium hemihydrate;Tiludronic acid diso
Tiludronate (Tiludronic Acid) disodium hemihydrate is an orally active bisphosphonate compound that functions as an osteoregulator. It is primarily utilized in metabolic bone disorder research. This compound acts as a potent inhibitor of the osteoclast vacuolar H+ -ATPase and possesses antiresorptive and anti-inflammatory properties[4].
价 格:¥电议型 号:T39037产 地:中国大陆
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T38791LY3020371;LY3020371LY3020371
LY3020371 is a highly potent and selective antagonist targeting the glutamate (mGlu) 2/3 receptor, showcasing excellent inhibition at Ki values of 5.26 nM and 2.50 nM for hmGluR2 and hmGluR3, respectively. With its remarkable affinity and specificity, LY3020371 serves as a valuable tool in depression research.
价 格:¥电议型 号:T38791产 地:中国大陆
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T38037Caffeic Acid-13C3;Caffeic Acid-13C3Caffeic Acid-13C3;Caffeic Acid-13C3
Caffeic acid-13C3 is an isotopically enriched form of caffeic acid that is intended for use as an internal standard for the quantification of caffeic acid by GC- or LC-MS. Caffeic acid is an inhibitor of 5-LO , with IC50 values of 3.7-72 μM, and 12-LO, with IC50 values of 5.1-30 μM.
价 格:¥电议型 号:T38037产 地:中国大陆
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T37731TPU-0037A;TPU-0037ATPU-0037A
TPU-0037A is an antibiotic and a congener of lydicamycin . It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs = 1.56-12.5 μg/ml), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs = >50 μg/ml).
价 格:¥电议型 号:T37731产 地:中国大陆
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T37546TPU-0037C;TPU-0037CTPU-0037C
TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to lydicamycin . It is active against Gram-positive bacteria (MICs = 0.39-3.13 μg/ml), including methicillin-resistant S. aureus strains (MIC = 3.13 μg/ml), but is ineffective against Gram-negative bacteria (MICs = >50 μg/ml).
价 格:¥电议型 号:T37546产 地:中国大陆