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T76037A-71915 TFA；化合物 A-71915 TFAA-71915 TFA
A-71915 (TFA) is a selective atrial natriuretic peptide-receptor (ANP receptor) inhibitor that promotes apoptosis and reduces insulin secretion in RINm5F pancreatic β-cells [1].
价 格：￥电议型 号：T76037产 地：中国大陆
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T75879Men 10376 TFA；化合物 Men 10376 TFAMen 10376 TFA
Men 10376 TFA is a selective antagonist of the tachykinin NK-2 receptor, displaying a K i value of 4.4 μM specifically for the NK-2 receptor in rat small intestine [1].
价 格：￥电议型 号：T75879产 地：中国大陆
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T75037N1-Methoxymethyl pseudouridine；化合物 N1-Methoxymethyl pseudouridineN1-Methoxymethyl pseudouridine
N1-Methoxymethyl pseudouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1] .
价 格：￥电议型 号：T75037产 地：中国大陆
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T74985MRV03-037；化合物 MRV03-037MRV03-037
MRV03-037, a selective colibactin-activated peptidase (ClbP) inhibitor, effectively inhibits the genotoxic effects of Colibactin on eukaryotic cells by blocking the production of gut bacterial genotoxins [1].
价 格：￥电议型 号：T74985产 地：中国大陆
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T74037DL-β-Hydroxybutyryl coenzyme A lithium；化合物 DL-β-Hydroxybutyryl coenzyme A lithiumDL-β-Hydroxybutyryl
DL-β-Hydroxybutyryl coenzyme A lithium, an intermediate in butyric acid fermentation and lysine and tryptophan metabolism, is synthesized from β-hydroxybutyric acid by short-chain-CoA synthase [1] [2].
价 格：￥电议型 号：T74037产 地：中国大陆
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T73037HSP90-IN-18；化合物 HSP90-IN-18HSP90-IN-18
HSP90-IN-18 is a potent inhibitor of heat shock protein 90 (Hsp90), demonstrating significant inhibitory activity with an IC50 value of 0.39 μM. It is applicable in the research of viral infections, neurodegenerative diseases, and inflammation.
价 格：￥电议型 号：T73037产 地：中国大陆
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T72073AKOS037652256；化合物AKOS037652256AKOS037652256
AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity such as lysosomal accumulation disorders, muscular dystrophy, common age-related neurodegenerative diseases, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing.
价 格：￥电议型 号：T72073产 地：中国大陆
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T72037Anti-Influenza agent 4；抗流感剂4Anti-Influenza agent 4
Anti-Influenza agent 4 is a potent and selective inhibitor of influenza virus, inhibiting A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively.
价 格：￥电议型 号：T72037产 地：中国大陆
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T71037BAY-438；化合物 BAY-438BAY-438
BAY-438 is an allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model.
价 格：￥电议型 号：T71037产 地：中国大陆
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T70801ZM-181037；化合物 ZM-181037ZM-181037
ZM-181037 is an ATP-sensitive potassium channel-blocker and a eukalemic diuretic.
价 格：￥电议型 号：T70801产 地：中国大陆
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T70407cemadotin free base；西马多丁LU103793 free base；LU103793 free base
Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks mitosis and inhibits microtubules (tubulin) with a Ki of 1 μM. Cemadotin is used in research against cancer.
价 格：￥电议型 号：T70407产 地：中国大陆
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T70379PF-04479745 tartrate；化合物 PF-04479745 tartratePF-04479745 tartrate
PF-04479745, also known as PF-4479745, is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measurable functional agonism at the key selectivity targets 5-HT2A and 5-HT2B in relevant tissue-based assay systems.
价 格：￥电议型 号：T70379产 地：中国大陆
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T70378EXP-561 monohydrate；化合物 EXP-561 monohydrateEXP-561 monohydrate
EXP-561 monohydrate is an investigational drug that acts as an inhibitor of the reuptake of serotonin, dopamine, and norepinephrine.
价 格：￥电议型 号：T70378产 地：中国大陆
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T70377BAY 61-3606 HCl；化合物 BAY 61-3606 HClBAY 61-3606 HCl
BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was shown to suppress antigen-induced passive cutaneous anaphylactic reaction, bronchoconstriction, and bronchial edema. It can also sensitize MCF-7 breast cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis by inhibiting Cdk9. This compound has been used i
价 格：￥电议型 号：T70377产 地：中国大陆
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T70376CHF-6366；化合物 CHF-6366CHF-6366
CHF-6366 is a dual-action chemical compound acting as a potent M3 muscarinic antagonist and β2-adrenergic receptors agonist, with respective pK i values of 10.4 and 11.4. Additionally, it exhibits weak calcium channel inhibitory properties (IC 50 ~50 μM) and demonstrates the ability to inhibit bronchoconstriction in guinea pigs, making it a viable candidate for chronic obstructive pulmonary disease (COPD) research.
价 格：￥电议型 号：T70376产 地：中国大陆
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T70375ZEN-2759；化合物ZEN-2759ZEN-2759
ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).
价 格：￥电议型 号：T70375产 地：中国大陆
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T70374LH-708；化合物 LH-708LH-708
LH-708 is an inhibitor of cystine stone formation for treatment of cystinuria.
价 格：￥电议型 号：T70374产 地：中国大陆
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T70373AS2575959；化合物 AS2575959AS2575959
AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.
价 格：￥电议型 号：T70373产 地：中国大陆
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T70372FTI-249；化合物 FTI-249FTI-249
FTI-249 is a Farnesyltransferase inhibitor, which potently inhibited FTase (IC50 = 100?–200 nM).
价 格：￥电议型 号：T70372产 地：中国大陆
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T70371Xylarianaphthol-1；化合物 Xylarianaphthol-1Xylarianaphthol-1
Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.
价 格：￥电议型 号：T70371产 地：中国大陆
