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T741883-Cyanovinylcarbazole phosphoramidite;化合物 3-Cyanovinylcarbazole phosphoramidite3-Cyanovinylcarbazole
3-Cyanovinylcarbazole phosphoramidite acts as an antiviral agent by hindering viral DNA synthesis. This compound features a modified nucleoside, produced by introducing a cyano group at the ribonucleotide´s C-3 position, enabling its utilization as a phosphoric acid amide in DNA synthesis [1].
价 格:¥电议型 号:T74188产 地:中国大陆
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T74128NCGC00188636;化合物 NCGC00188636NCGC00188636
NCGC00188636, a novel covalent pyruvate kinase (PYK) inhibitor, obstructs nucleotide binding to PYK´s active site, rendering it instrumental for research into the metabolism across various organisms and cell types.
价 格:¥电议型 号:T74128产 地:中国大陆
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T7334NP118809;化合物NP11880939-1B4;39-1B4|||1-【4-(二苯甲基)-1-哌嗪基】-3,3-二苯基-1-丙酮
NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
价 格:¥电议型 号:T7334产 地:中国大陆
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T73188RK-0133114;化合物 RK-0133114RK-0133114
RK-0133114, a G9a inhibitor and the R-enantiomer of RK-701, exhibits potent inhibition of G9a with an IC50 value of 3.7 μM. This compound is utilized in research focused on sickle cell disease (SCD) [1].
价 格:¥电议型 号:T73188产 地:中国大陆
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T72188Nicotinamide Hydrochloride;化合物 Nicotinamide HydrochlorideNiacinamide Hydrochloride|||Nicotinic acid
Nicotinamide Hydrochloride is a form of vitamin B3 or niacin that inhibits sirtuin 2 ( SIRT2 ) activity in vitro , with an EC 50 of 2 μM. Nicotinamide Hydrochloride inhibits up to 90% melanoma cell number and increases cellular NAD + , ATP, ROS levels. Nicotinamide Hydrochloride inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma [1] .
价 格:¥电议型 号:T72188产 地:中国大陆
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T71889Esoxybutynin Chloride;化合物 Esoxybutynin ChlorideEsoxybutynin Chloride
Esoxybutynin Chloride is (S)-enantiomer of oxybutynin. Esoxybutynin Chloride exerts antimuscarinic properties. Racemic oxybutynin is used clinically to treat urinary incontinence. Sepracor was developing (S)-oxybutynin, a single-isomer version of Alza´s Ditropan (racemic oxybutynin), a muscarinic acetylcholine receptor antagonist, as a potential treatment for urinary incontinence.
价 格:¥电议型 号:T71889产 地:中国大陆
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T71888Fenclonine hydrochloride;化合物 Fenclonine hydrochlorideFenclonine hydrochloride
Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.
价 格:¥电议型 号:T71888产 地:中国大陆
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T71887Hydroquinone monobenzoate;化合物 Hydroquinone monobenzoateHydroquinone monobenzoate
Hydroquinone monobenzoate is an oxidoreductant and potential topoisomerase II inhibitor commercially used in skin whitening treatments and photography development. It may induce DNA damage.
价 格:¥电议型 号:T71887产 地:中国大陆
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T71886ALN29882;化合物 ALN29882ALN29882
ALN29882 is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage. 18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant p
价 格:¥电议型 号:T71886产 地:中国大陆
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T71885Sodium 2-mercaptobenzothiazole;化合物 Sodium 2-mercaptobenzothiazoleSodium 2-mercaptobenzothiazole
Sodium 2-mercaptobenzothiazole is the sodium salt of mercaptobenzothiazole, and is used as a copper corrosion inhibitor.
价 格:¥电议型 号:T71885产 地:中国大陆
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T71884?-Carboline-1-carboxylic acid;化合物 ?-Carboline-1-carboxylic acid?-Carboline-1-carboxylic acid
β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 ?g/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 ?g/ml, respectively) but not Hep
价 格:¥电议型 号:T71884产 地:中国大陆
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T71883Paraxazone;化合物 ParaxazoneParaxazone
Paraxazone is an antidepressant. It acts as a reversible inhibitor of the enzyme monoamine oxidase.
价 格:¥电议型 号:T71883产 地:中国大陆
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T71882Pifexole;化合物 PifexolePifexole
Pifexole is the 1,2,4-oxadiazole derivative. It has a similar profile of muscle-relaxant activity in animals to that of chlorzoxazone. In rats, pifexole is reported to be seven times more potent than chlorzoxazone in inhibition of strychnine-induced convulsions.
价 格:¥电议型 号:T71882产 地:中国大陆
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T71881Bromophenol red;化合物 Bromophenol redBromophenol red
Bromophenol red (BPR) is a chemical indicator. It has been shown to bind to lysozymes and inhibits their activity against bacterial cell walls, but not against the polysaccharide component of peptidoglycan.
价 格:¥电议型 号:T71881产 地:中国大陆
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T71880Irgarol;化合物 IrgarolIrgarol
Irgarol is a highly specific and effective inhibitor of photosynthesis.
价 格:¥电议型 号:T71880产 地:中国大陆
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T7188Piclidenoson;化合物PiclidenosonCF-101|||IB-MECA;CF-101|||IB-MECA
Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.
价 格:¥电议型 号:T7188产 地:中国大陆
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T71824CSV0C018875 Hydrochloride;化合物 CSV0C018875 HydrochlorideCSV0C018875 Hydrochloride
CSV0C018875 Hydrochloride is a novel G9a (EHMT2) inhibitor, binding tightly inside the active site cavity of G9a, inhibiting the activity of G9a in both enzyme and cell based assays with much lesser toxicity than BIX-0129.
价 格:¥电议型 号:T71824产 地:中国大陆
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T71741PPK-188;化合物 PPK-188PPK-188
PPK-188, also known as CFT, is a novel selective covalent inhibitor of tryparedoxin (tpx), efficiently killing live african trypansosomes
价 格:¥电议型 号:T71741产 地:中国大陆
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T71188LY2780301;化合物 LY2780301LY2780301
LY2780301 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor LY2780301 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway, thereby leading to inhibition of cell proliferation and the induction of apoptosis in tumor cells. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signa
价 格:¥电议型 号:T71188产 地:中国大陆
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T71083LDN-193188;化合物 LDN-193188LDN-193188
LDN-193188 is a inhibitor of phosphatidylcholine transfer protein (PC-TP).
价 格:¥电议型 号:T71083产 地:中国大陆