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T62188PIM1-IN-6；化合物 PIM1-IN-6PIM1-IN-6
PIM1-IN-6 (compound 5h) is a potent inhibitor of PIM-1 (IC50: 0.60 μM).PIM1-IN-6 has a high cytotoxic effect on HCT-116 and MCF-7 cells with IC50 values of 1.51 and 15.2 μM, respectively.
价 格：￥电议型 号：T62188产 地：中国大陆
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T6195Baloxavir marboxil；化合物Baloxavir marboxilS 033188|||S-033188|||Influenza Virus|||S-033188|||inhibit||
Baloxavir marboxil (S-033188) is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
价 格：￥电议型 号：T6195产 地：中国大陆
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T61889Benoxathian hydrochloride；化合物 Benoxathian hydrochlorideBenoxathian hydrochloride
Benoxathian hydrochloride is effective α 1 Adrenaline receptor antagonist. Benoxathian hydrochloride has value in the study of anorexia.
价 格：￥电议型 号：T61889产 地：中国大陆
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T61888mTOR/HDAC6-IN-1；化合物 mTOR/HDAC6-IN-1mTOR/HDAC6-IN-1
mTOR/HDAC6-IN-1 is an effective dual inhibitor of histone deacetylase (HDAC6) and mammalian rapamycin (mTOR). The IC50 values for HDAC6 and mTOR are 56 nM and 133.7 nM respectively. MTOR/HDAC6-IN-1 can significantly induce autophagy and apoptosis and inhibit migration. MTOR/HDAC6-IN-1 has potential in the study of triple negative breast cancer (TNBC).
价 格：￥电议型 号：T61888产 地：中国大陆
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T61887RIPK1-IN-13；化合物 RIPK1-IN-13RIPK1-IN-13
RIPK1-IN-13 (Compound 8) is an effective RIPK1 inhibitor (IC50=1139 nM). By inhibiting RIPK1, RIPK1-IN-13 can block the activation of necrotic apoptosis pathway. RIPK1-IN-13 has research potential in inflammatory diseases.
价 格：￥电议型 号：T61887产 地：中国大陆
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T61886HBV-IN-16；化合物 HBV-IN-16HBV-IN-16
HBV-IN-16 is a quinoline derivative, which has an effective inhibitory effect on covalent closed circular DNA (cccDNA). CccDNA is the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-16 has potential in the research of HBV infection.
价 格：￥电议型 号：T61886产 地：中国大陆
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T61885Sulconazole；化合物 SulconazoleSulconazole
Sulconazole is an imidazole compound with effective antifungal effect. Sulconazole vs. NF- κ B/IL-8 signal pathway has blocking effect and inhibiting effect on the formation of cancer stem cells (CSC). Sulconazole has inhibitory effect on tumor growth, which can be used in breast cancer research.
价 格：￥电议型 号：T61885产 地：中国大陆
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T61884C6 Ceramide；C6神经酰胺N-hexanoylsphingosine|||N-(hexanoyl)sphing-4-enine；N-hexanoylsphingosine|||N-(hexa
C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK. It can act in a variety of cancer cell lines.
价 格：￥电议型 号：T61884产 地：中国大陆
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T61883ARN5187；化合物 ARN5187ARN5187
ARN5187 is a lysosomal compound, REV-ERB β Ligand. ARN5187 inhibits REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 shows lysosomal efficacy and cytotoxicity, and can induce apoptosis.
价 格：￥电议型 号：T61883产 地：中国大陆
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T61882AT791；化合物 AT791AT791
AT791 is an effective TLR7 and TLR9 inhibitor with oral activity. AT791 has inhibitory effects on TLR7 and TLR9 signal transduction in various types of human and mouse cells. AT791 inhibits DNA-TLR9 interaction in vitro.
价 格：￥电议型 号：T61882产 地：中国大陆
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T61881γ-Secretase modulator 12；化合物 γ-Secretase modulator 12γ-Secretase modulator 12
γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM. It is specifically designed for Alzheimer´s disease research. Notably, γ-Secretase modulator 12 exhibits a favorable brain/plasma ratio (Kp, brain = 0.72) in mice [1].
价 格：￥电议型 号：T61881产 地：中国大陆
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T61880Tubulin polymerization-IN-26；化合物 Tubulin polymerization-IN-26Tubulin polymerization-IN-26
Tubulin polymerization-IN-26 (compound 12h) is a chemical compound that inhibits the polymerization of microtubulin. It achieves this by binding to the colchicine binding site of microtubulin, with an IC50 value of 4.64 μM. Additionally, Tubulin polymerization-IN-26 has the ability to induce apoptosis and inhibit cell metastasis or migration. Due to these properties, it holds potential as a valuable compound for researching lung cancer [1].
价 格：￥电议型 号：T61880产 地：中国大陆
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T6188Desvenlafaxine succinate hydrate；琥珀酸去甲文拉法辛O-Desmethylvenlafaxine succinate hydrate|||WY 45233 Succin
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
价 格：￥电议型 号：T6188产 地：中国大陆
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T61188Chitin synthase inhibitor 2；化合物 Chitin synthase inhibitor 2Chitin synthase inhibitor 2
Chitin synthase inhibitor 2 (compound 2b) is a highly potent inhibitor of chitin synthase, with an IC50 value of 0.09 mM and a K i value of 0.12 mM. This compound exhibits antimicrobial activities in vitro and demonstrates synergistic or additive effects when combined with fluconazole or polyoxin B [1].
价 格：￥电议型 号：T61188产 地：中国大陆
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T60786CSV0C018875；化合物 CSV0C018875CSV0C018875
CSV0C018875 is a quinoline-based EHMT2/G9a inhibitor with lower cytotoxicity than BIX-01294 [1].
价 格：￥电议型 号：T60786产 地：中国大陆
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T6069Gemcitabine hydrochloride；盐酸吉西他滨Gemcitabine HCl|||Gemzar|||LY188011|||LY 188011 hydrochloride；Gemcit
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
价 格：￥电议型 号：T6069产 地：中国大陆
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T5S1889Yunaconitine；滇乌头碱Guayewuanine B；Guayewuanine B|||滇乌头碱
1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows positive effect in the granuloma inhibition test when it was subcutaneously injected, 1 μg/kg for 6 d, or added directly to the cotton-pellet. 4. Yunaconitine inhibited the increased vascular permeability caused byacetic acid and histamine, the leucocyte migratory response induced
价 格：￥电议型 号：T5S1889产 地：中国大陆
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T5S1882Songorine；一枝蒿庚素Napellonine|||Zongorine|||Bullatine G；准葛尔乌头碱|||Napellonine|||Zongorine|||Bullatine G
Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.
价 格：￥电议型 号：T5S1882产 地：中国大陆
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T5188GC376 sodium；化合物GC376 sodiumGC376 sodium
GC376 is an inhibitor of 3C-like proteases (3CLpro) with IC50 values range from 0.49~4.35 μM.
价 格：￥电议型 号：T5188产 地：中国大陆
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T4S1881Aconine；乌头原碱Jesaconine；乌头原碱|||Jesaconine
1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.
价 格：￥电议型 号：T4S1881产 地：中国大陆
