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T18591Propargyl-PEG8-SH;化合物 T18591Propargyl-PEG8-SH
Propargyl-PEG8-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18591产 地:中国大陆
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T17591Biotin-PEG6-Boc;生物素-六聚乙二醇-丙酸叔丁酯Biotin-PEG6-t-butyl ester;生物素-六聚乙二醇-丙酸叔丁酯|||Biotin-PEG6-t-butyl ester
Biotin-PEG6-Boc (Biotin-PEG6-t-butyl ester) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17591产 地:中国大陆
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T16591Propargyl-PEG1-SS-PEG1-PFP ester;化合物 T16591Propargyl-PEG1-SS-PEG1-PFP ester
Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T16591产 地:中国大陆
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T16339Norverapamil hydrochloride;盐酸去甲维拉帕米(±)-Norverapamil hydrochloride|||D591 hydrochloride;(±)-Norverapa
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
价 格:¥电议型 号:T16339产 地:中国大陆
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T16098Islatravir;化合物IslatravirMK-8591;MK-8591
Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).
价 格:¥电议型 号:T16098产 地:中国大陆
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T16087Quiflapon;喹夫拉朋MK-591;喹夫拉朋|||MK-591
Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively).
价 格:¥电议型 号:T16087产 地:中国大陆
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T16022Arhalofenate;芳卤芬酯JNJ 39659100|||MBX 102;JNJ 39659100|||芳卤芬酯|||4-氯-ALPHA-[3-(三氟甲基)苯氧基]苯乙酸 2-(乙酰基氨基)乙酯
Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.
价 格:¥电议型 号:T16022产 地:中国大陆
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T1591LCytidine;胞苷Cytosine-1-β-D-ribofuranoside|||Cytosine β-D-riboside;Cytosine-1-β-D-ribofuranoside|||胞苷|
Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.
价 格:¥电议型 号:T1591L产 地:中国大陆
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T15919m-PEG7-4-nitrophenyl carbonate;化合物m-PEG7-4-nitrophenyl carbonatem-PEG7-4-nitrophenyl carbonate
m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
价 格:¥电议型 号:T15919产 地:中国大陆
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T15918m-PEG6-Tos;化合物 T15918m-PEG6-Tos
m-PEG6-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15918产 地:中国大陆
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T15917m-PEG6-thiol;化合物 T15917m-PEG6-thiol
m-PEG6-thiol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15917产 地:中国大陆
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T15916m-PEG6-O-CH2COOH;化合物 T15916m-PEG6-O-CH2COOH
m-PEG6-O-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15916产 地:中国大陆
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T15915m-PEG6-NHS ester;化合物 T15915m-PEG6-NHS ester
m-PEG6-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T15915产 地:中国大陆
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T15914m-PEG6-CH2CH2COOH;化合物 T15914m-PEG6-CH2CH2COOH
m-PEG6-CH2CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15914产 地:中国大陆
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T15913m-PEG6-CH2CH2CHO;化合物 T15913m-PEG6-CH2CH2CHO
m-PEG6-CH2CH2CHO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T15913产 地:中国大陆
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T15911m-PEG7-CH2-OH;化合物 T15911m-PEG7-CH2-OH
m-PEG7-CH2-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15911产 地:中国大陆
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T1591Ancitabine hydrochloride盐酸环胞苷NSC 145668 HCl|||盐酸环胞苷|||Cyclocytidine hydrochloride|||Cyclo-CMP hydroc
Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycl
价 格:¥电议型 号:T1591产 地:中国大陆
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T15654Ketohexokinase inhibitor 1;化合物Ketohexokinase inhibitor 1PF-06835919;PF-06835919
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively).
价 格:¥电议型 号:T15654产 地:中国大陆
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T15591Ipenoxazone;伊培沙宗NC-1200|||MLV-6976;NC-1200|||MLV-6976|||伊培沙宗
Ipenoxazone is an effective and centrally acting muscle relaxant.
价 格:¥电议型 号:T15591产 地:中国大陆
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T14591Biotin-PEG3-azideN-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺N-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺
Biotin-PEG3-azide is a PEG-based PROTAC linker can be used in PROTAC synthesis.
价 格:¥电议型 号:T14591产 地:中国大陆