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  • T59125-Methylcytidine；5-甲基胞苷5-Methylcytidine

    5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.

    价 格：￥电议型 号：T5912产 地：中国大陆

  • T4591Dihydrokavain；二氢醉椒素Marindinin|||7,8-Dihydrokavain|||7,8-Dihydrokawain；Marindinin|||二氢醉椒素|||7,8-Dihyd

    Dihydrokavain (Marindinin), a prominent kavalactone in the kava plant, significantly contributes to the plant´s anxiolytic effects, as evidenced by a study conducted on chicks.

    价 格：￥电议型 号：T4591产 地：中国大陆

  • T3S1591Notoginsenoside Fc三七皂苷 FC三七皂苷 FC|||三七皂苷Fc

    1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.

    价 格：￥电议型 号：T3S1591产 地：中国大陆

  • T39652BODIPY 581/591 C11；BODIPY 581/591 C11BODIPY 581/591 C11；BODIPY 581/591 C11

    C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation . C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 is applied in the quantitation of ferroptosis.

    价 格：￥电议型 号：T39652产 地：中国大陆

  • T39591Human PD-L1 inhibitor IHuman PD-L1 inhibitor IHuman PD-L1 inhibitor I

    Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1. It exhibits a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 inhibitor I disrupts the binding between human PD-L1 and human PD-1, thereby attenuating their respective functions.

    价 格：￥电议型 号：T39591产 地：中国大陆

  • T38591Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)；Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)Biotinyl-NH-PEG3-

    Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, utilized for synthesizing PROTACs.

    价 格：￥电议型 号：T38591产 地：中国大陆

  • T37591IMP-1710；化合物IMP-1710IMP-1710

    IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.

    价 格：￥电议型 号：T37591产 地：中国大陆

  • T36981GSK 591 dihydrochlorideGSK 591 dihydrochlorideGSK 591 dihydrochloride

    Potent and selective PRMT5 inhibitor (IC50 = 4 nM). Selective for PRMT5 over a panel of other PRMTs and lysine methyltransferases. Inhibits proliferation of mantle cell lymphoma (MCL) in vitro. To request the negative control for GSK 591, please fill out the SGC 2096 request form on the SGC website.

    价 格：￥电议型 号：T36981产 地：中国大陆

  • T35919N-hydroxy Riluzole；N-hydroxy RiluzoleN-hydroxy Riluzole

    N-hydroxy Riluzole is a metabolite of the antiglutamatergic agent riluzole .1It is formed from riluzole predominantly by the cytochrome P450 (CYP) isoform CYP1A2 in human hepatic microsomes.

    价 格：￥电议型 号：T35919产 地：中国大陆

  • T35918N-Arachidonoyl Taurine；N-Arachidonoyl TaurineN-Arachidonoyl Taurine

    N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretio

    价 格：￥电议型 号：T35918产 地：中国大陆

  • T35916Simotinib；西莫替尼AL-6802|||SIM-6802；AL-6802|||SIM-6802

    Simotinib (AL-6802) is a selective and orally bioactive EGFR tyrosine kinase inhibitor (IC50: 19.9 nM) with anti-tumour activity for the study of non-small cell lung cancer.

    价 格：￥电议型 号：T35916产 地：中国大陆

  • T35915Erlotinib-13C6；Erlotinib-13C6Erlotinib-13C6；Erlotinib-13C6

    Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

    价 格：￥电议型 号：T35915产 地：中国大陆

  • T35914Epitinib succinate；琥珀酸EpitinibHMPL-813 succinate；HMPL-813 succinate

    Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.

    价 格：￥电议型 号：T35914产 地：中国大陆

  • T35913EMI56；EMI56EMI56

    EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].

    价 格：￥电议型 号：T35913产 地：中国大陆

  • T35912Pyrocoll；PyrocollPyrocoll

    Pyrocoll is a bacterial metabolite originally isolated from Streptomyces. It inhibits the growth of A. aurescens, A. globiformis, A. oxydans, A. pascens, and R. erythropolis bacteria (MICs = 10, 1, 10, 3, and 10 μg/ml, respectively) and HMO2, HepG2, and MCF-7 cancer cells (GI50s = 0.28, 0.42, and 2.2 μg/ml, respectively) in vitro. Pyrocoll is also active against P. falciparum and T. rhodesiense (IC50s = 1.19 and 1.97 μg/ml, respectively).

    价 格：￥电议型 号：T35912产 地：中国大陆

  • T35911Piliformic Acid；Piliformic AcidPiliformic Acid

    Piliformic acid is a fungal metabolite that has been found inN. pseudotrichiaand has diverse biological activities.1,2It is cytotoxic to BC-1 human breast cancer cells (IC50= 5 μg/ml).2Piloformic acid is active againstL. braziliensisamastigotes (IC50= 78.5 μM). It is also active against the plant pathogenic fungiC. gloeosporioides(MIC = 292 μM).1

    价 格：￥电议型 号：T35911产 地：中国大陆

  • T35910Petromurin C；Petromurin CPetromurin C

    Petromurin C is a bis-indolyl benzenoid fungal metabolite originally isolated from the ascostromata of P. muricatus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 33 μg/ml) and has activity against T. foetus in vitro (IC50 = 100 μg/ml).

    价 格：￥电议型 号：T35910产 地：中国大陆

  • T3591URB602；化合物URB602URB602

    URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.

    价 格：￥电议型 号：T3591产 地：中国大陆

  • T35812CAY10591；CAY10591CAY10591；CAY10591

    Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1, such as resveratrol, extend lifespan in yeast and C. elegans in a manner that resembles caloric restriction. CAY10591 has been identified as an activator of the enzyme SIRT1. This com

    价 格：￥电议型 号：T35812产 地：中国大陆

  • T35591Guanfacine-13C,15N3；Guanfacine-13C,15N3Guanfacine-13C,15N3；Guanfacine-13C,15N3

    Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin

    价 格：￥电议型 号：T35591产 地：中国大陆

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