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  • T80500Jingzhaotoxin-X；化合物 Jingzhaotoxin-XJZTX-X；JZTX-X

    Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].

    价 格：￥电议型 号：T80500产 地：中国大陆

  • T80502-Methyltetrahydrofuran-3-one；2-甲基四氢呋喃-3-酮2-Methyltetrahydrofuran-3-one

    2-Methyltetrahydrofuran-3-one, also known as fema 3373 or tetrahydro-2-methyl-3-furanone, belongs to the class of organic compounds known as furanones.

    价 格：￥电议型 号：T8050产 地：中国大陆

  • T798055-HT2 agonist-1 free base；化合物 5-HT2 agonist-1 free base5-HT2 agonist-1 free base

    Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. It is utilized in research pertaining to depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders, and other central nervous system disorders. [1]

    价 格：￥电议型 号：T79805产 地：中国大陆

  • T78805AD4；化合物 AD4AD4

    AD4, an artemisinin derivative functioning as a proteolytic targeting chimera (PROTAC) for PCLAF, effectively degrades PCLAF in RS4;11 cells with an IC50 of 0.6 nM. This degradation activates the p21/Rb axis, resulting in antitumor activity. Furthermore, AD4 has been demonstrated to prolong survival in NOD/SCID mice transplanted with RS4;11 cells, showcasing its in vivo efficacy [1].

    价 格：￥电议型 号：T78805产 地：中国大陆

  • T78212RMC-9805；化合物 RMC-9805KRAS G12D inhibitor 18|||KRAS G12D IN 18；KRAS G12D inhibitor 18|||KRAS G12D IN

    RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.

    价 格：￥电议型 号：T78212产 地：中国大陆

  • T78059Glucagon (Human)；化合物 Glucagon (Human)Hyperglycemic-glycogenolytic factor|||Glukagon；Hyperglycemic-gl

    Glucagon significantly impacts protein and amino acid metabolism. It hinders the integration of amino acids into the proteins of the liver, muscle, and pancreas, augmenting nitrogen excretion and stimulating hepatic urea synthesis. Additionally, it elevates hepatic transaminase and urea cycle enzyme levels. Glucagon also enhances hepatic amino acid uptake, facilitating their conversion into liver glycogen, and reduces blood amino acid concentrations [1].

    价 格：￥电议型 号：T78059产 地：中国大陆

  • T78058Verazine；化合物 Verazine(-)-Verazine；(-)-Verazine

    (-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. It has applications in research related to fungal infections and neurological diseases [1] [2].

    价 格：￥电议型 号：T78058产 地：中国大陆

  • T78057Windaus ketone；化合物 Windaus ketoneWindaus ketone

    Windaus ketone functions as a vitamin D (VD) synthesis inhibitor.

    价 格：￥电议型 号：T78057产 地：中国大陆

  • T78056HMGB1-IN-1；化合物 HMGB1-IN-1HMGB1-IN-1

    HMGB1-IN-1 (compound 6) exhibits potent inhibition of NO production in RAW264.7 cells, with an IC50 of 15.9 ± 0.6 μM, and effectively disrupts the HMGB1/NF-κB/NLRP3 signaling pathway. This compound demonstrates promising anti-inflammatory and anti-sepsis properties, particularly in the context of renal injury [1].

    价 格：￥电议型 号：T78056产 地：中国大陆

  • T78055MYC-RIBOTAC；化合物 MYC-RIBOTACMYC-RIBOTAC

    MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. This interaction promotes the degradation of MYC mRNA, subsequently reducing MYC protein levels and inducing apoptosis, thereby presenting potential applications in anticancer research [1].

    价 格：￥电议型 号：T78055产 地：中国大陆

  • T78054JNJ-1013；化合物 JNJ-1013JNJ-1013

    JNJ-1013 is a potent and selective IRAK1 degrader, demonstrating IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis and augments the expression of cleaved PARP while decreasing the expression of IRAK1, p-IKBα, and pSTAT3(Tyr705) [1].

    价 格：￥电议型 号：T78054产 地：中国大陆

  • T78053PD-L1-IN-2；化合物 PD-L1-IN-2PD-L1-IN-2

    PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity. In vivo studies indicate that it suppresses PD-L1 expression and amplifies tumor-infiltrating T-cell response, thus exerting anticancer effects. This compound is particularly utilized in the investigation of colorectal cancer [1].

    价 格：￥电议型 号：T78053产 地：中国大陆

  • T78052Acifluorfen-methyl；化合物 Acifluorfen-methylAcifluorfen-methyl

    Acifluorfen-methyl, a photobleaching herbicide [1], functions as an inhibitor of the enzyme protoporphyrinogen oxidase (Protox), which is crucial for heme and chlorophyll biosynthesis.

    价 格：￥电议型 号：T78052产 地：中国大陆

  • T78051Necrocide 1；化合物 Necrocide 1Necrocide 1

    Necrocide 1 (compound (S)-38), a potent anticancer agent, exhibits antiproliferative activity with IC50 values of 0.48 nM for MCF-7 and 2 nM for PC3 cancer cell lines, respectively [1].

    价 格：￥电议型 号：T78051产 地：中国大陆

  • T78050WH-10417-099；化合物 WH-10417-099WH-10417-099

    WH-10417-099 is a degrader capable of inducing the degradation of an extensive array of unique kinases, exceeding 125 in total [1].

    价 格：￥电议型 号：T78050产 地：中国大陆

  • T7805GW791343 dihydrochloride；化合物GW791343 dihydrochlorideGW791343 (HCl)；GW791343 (HCl)

    GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator.

    价 格：￥电议型 号：T7805产 地：中国大陆

  • T77805KRAS G12C mutant protein inhibitor A-1；化合物 KRAS G12C mutant protein inhibitor A-1KRAS G12C mutant pr

    KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.

    价 格：￥电议型 号：T77805产 地：中国大陆

  • T76805Epratuzumab；化合物 EpratuzumabEpratuzumab

    Epratuzumab (Antibody hLL 2), an anti-CD22 IgG1 monoclonal antibody, serves as both a tumor-imaging and immunomodulatory agent. It induces CD22 phosphorylation and has been employed in researching Non-Hodgkin’s Lymphomas (NHL) and select autoimmune diseases [1].

    价 格：￥电议型 号：T76805产 地：中国大陆

  • T75805Antisauvagine-30 TFA；化合物 Antisauvagine-30 TFAAntisauvagine-30 TFA

    Antisauvagine-30 TFA (aSvg-30 TFA), a potent peptidic antagonist specific to the CRF 2 receptor, demonstrates high selectivity and competitive interaction. It shows dissociation constants (Kd) of 1.4 nM for mCRFR2β and 150 nM for CRFR1, highlighting its efficacy [1] [2] [3] [4].

    价 格：￥电议型 号：T75805产 地：中国大陆

  • T7388GSK805；化合物GSK805GSK805

    GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor´s putative ligand binding domain without exerting significant effects on DNA binding

    价 格：￥电议型 号：T7388产 地：中国大陆

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