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T80519m3-Huwentoxin IV;化合物 m3-Huwentoxin IVm3-HwTx-IV;m3-HwTx-IV
m3-Huwentoxin IV (m3-HwTx-IV) is a potent inhibitor of sodium channels (NaV), exhibiting half-maximal inhibitory concentrations (IC50s) of 3.3 nM for hNaV1.7, 6.8 nM for hNaV1.6, 7.2 nM for hNaV1.3, 8.4 nM for hNaV1.1, 11.9 nM for hNaV1.2, and 369 nM for hNaV1.4 in the QPatch assay. It also dose-dependently alleviates spontaneous pain in a rodent model when induced by the NaV1.7 activator OD1 [1].
价 格:¥电议型 号:T80519产 地:中国大陆
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T80518Mambalgin-3;化合物 Mambalgin-3Mambalgin-3
Mambalgin-3, an acid-sensitive ion channel 1 (ASIC1) inhibitor, has potential applications in analgesia research [1].
价 格:¥电议型 号:T80518产 地:中国大陆
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T80517Ala5-Galanin (2-11);化合物 Ala5-Galanin (2-11)Ala5-Galanin (2-11)
Ala5-Galanin (2-11) is a specific agonist for the galanin receptor 2 (GAL2R) with an affinity constant (Ki) of 258 nM [1].
价 格:¥电议型 号:T80517产 地:中国大陆
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T80516human GALP (3-32);化合物 human GALP (3-32)Galanin-like peptide (3-32);Galanin-like peptide (3-32)
Human GALP (3-32) (Galanin-like peptide (3-32)) serves as a high-affinity agonist for galanin receptors GalR1 (IC50 = 33 nM) and GalR2 (IC50 = 15 nM), as evidenced by competitive binding studies. It demonstrates significant potency in modifying the extracellular acidification rate in SH-SY5Y cells expressing GalR2 (EC50 = 360 nM) [1].
价 格:¥电议型 号:T80516产 地:中国大陆
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T80515β-Endorphin (1-27) (human);化合物 β-Endorphin (1-27) (human)β-Endorphin (1-27) (human)
β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17, and 39.82 nM, respectively. It inhibits analgesia induced by both β-Endorphin and etorphine [1] [2].
价 格:¥电议型 号:T80515产 地:中国大陆
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T80514TAT-SAMβA;化合物 TAT-SAMβATAT-SAMβA
TAT-SAMβA, an RNAENFDRF (SAMβA) peptide conjugated to the TAT 47–57 protein-derived cell-penetrating peptide, acts as a selective antagonist of the Mfn1-βIIPKC association. It has been shown to protect mouse embryonic fibroblast cells (MEFs) from cytotoxicity induced by oxidative stress [1].
价 格:¥电议型 号:T80514产 地:中国大陆
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T80513YVAD-CHO;化合物 YVAD-CHOYVAD-CHO
YVAD-CHO is an inhibitor of interleukin-1β converting enzyme (ICE, caspase 1) that has been shown to partially mitigate motoneuron death in mice with lesioned facial nerves [1].
价 格:¥电议型 号:T80513产 地:中国大陆
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T80512Thrombin receptor peptide ligand;化合物 Thrombin receptor peptide ligandThrombin receptor peptide ligan
Thrombin receptor peptide ligand, a thrombin receptor antagonist, serves as an antithrombotic agent [1].
价 格:¥电议型 号:T80512产 地:中国大陆
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T80511PKCε inhibitor peptide,myristoylated;化合物 PKCε inhibitor peptide,myristoylatedMyr‐PKC?-;Myr‐PKC?-
Myristoylated PKCε inhibitor peptide (Myr-PKCε-) is a cell-permeable inhibitor consisting of a peptide linked to myristic acid that specifically inhibits protein kinase C epsilon (PKCε), consequently diminishing nitric oxide (NO) release in cultured human umbilical vein endothelial cells (HUVECs) [1].
价 格:¥电议型 号:T80511产 地:中国大陆
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T80510Tertiapin-RQ;化合物 Tertiapin-RQTertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].
价 格:¥电议型 号:T80510产 地:中国大陆
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T8051Bis(2-methyl-3-furyl)disulfide;双(2-甲基-3-呋喃基)二硫Bis(2-methyl-3-furyl)disulphide;双(2-甲基-3-呋喃基)二硫|||Bis(
Bis(2-methyl-3-furyl)disulfide is a volatile sulfur compound that is a key contributor to the meat-like aroma in cooked meat.
价 格:¥电议型 号:T8051产 地:中国大陆
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T80509PKC 20-28,myristoylated;化合物 PKC 20-28,myristoylatedMyristoylated protein kinase C inhibitor 20-28;My
Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].
价 格:¥电议型 号:T80509产 地:中国大陆
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T80508PKCη pseudosubstrate inhibitor,myristoylated;化合物 PKCη pseudosubstrate inhibitor,myristoylatedPKCη ps
Myristoylated PKCη pseudosubstrate inhibitor is a cell-permeable compound utilized to investigate the mechanism of action of PKCη [1].
价 格:¥电议型 号:T80508产 地:中国大陆
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T80507PKCθ pseudosubstrate peptide inhibitor,myristoylated;化合物 PKCθ pseudosubstrate peptide inhibitor,myri
Myristoylated PKCθ pseudosubstrate peptide inhibitor is a synthetic peptide utilized to investigate the mechanism of action of protein kinase C theta (PKCθ) [1].
价 格:¥电议型 号:T80507产 地:中国大陆
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T80506TAT-M2NX;化合物 TAT-M2NXtatM2NX;tatM2NX
TAT-M2NX (tatM2NX) is a selective TRPM2 inhibitor that exhibits neuroprotective effects in male mice. It is utilized in research to investigate ischemic neuronal injury [1].
价 格:¥电议型 号:T80506产 地:中国大陆
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T80505PKCα (C2-4) inhibitor peptide;化合物 PKCα (C2-4) inhibitor peptidePKCα (C2-4) inhibitor peptide
PKCα (C2-4) inhibitor peptide is a specific antagonist to PKCα that impedes the α1A-adrenoreceptor agonist A-61603 [1] from inhibiting I_Kr.
价 格:¥电议型 号:T80505产 地:中国大陆
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T80504?PKC(85–92),Myristoylated;化合物 ?PKC(85–92),Myristoylated?PKC(85–92),Myristoylated
PKC(85-92),Myristoylated is a myristic acid-conjugated, cell-permeable peptide activator of PKC that has been shown to increase nitric oxide (NO) release in cultured human umbilical vein endothelial cells (HUVECs) [1].
价 格:¥电议型 号:T80504产 地:中国大陆
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T80503Proadrenomedullin (N-20) (bovine, porcine);化合物 Proadrenomedullin (N-20) (bovine, porcine)ProADM N20(
Proadrenomedullin (N-20) (ProADM N20) (bovine, porcine) is a peptide known for its strong hypotensive effects and inhibition of catecholamine release from chromaffin cells without competing with other substances. It effectively suppresses catecholamine secretion in PC12 pheochromocytoma cells with an IC50 of 350 nM and prevents the desensitization of nicotinic cholinergic agonist-induced catecholamine release and nicotinic signal transduction, with an EC50 of approximately 270 nM for desensitiza
价 格:¥电议型 号:T80503产 地:中国大陆
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T80502P4pal10;化合物 P4pal10P4pal10
P4pal10, a PAR 4 antagonist, inhibits thrombin-mediated aggregation of mouse platelets in vivo and significantly diminishes Carrageenan-induced edema and granulocyte infiltration [1].
价 格:¥电议型 号:T80502产 地:中国大陆
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T80501Myr-TAT-CBD3;化合物 Myr-TAT-CBD3Myr-TAT-CBD3
Myr-TAT-CBD3, a CRMP2-CaV2.2 interaction inhibitor, has been shown to significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal hypersensitivity in a rat model of postoperative pain, making it a useful compound for studying inflammation and postoperative pain [1].
价 格:¥电议型 号:T80501产 地:中国大陆