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T1859AZD8055AZD8055
AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.
价 格:¥电议型 号:T1859产 地:美洲
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T2485BaricitinibBaricitinib,LY3009104,INCB028050
Baricitinib is an orally bioavailable inhibitor of Janus kinases 1 and 2 (JAK1/2), with potential anti-inflammatory, immunomodulating and antineoplastic activities.
价 格:¥电议型 号:T2485产 地:美洲
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T2501Canertinib dihydrochlorideCanertinib dihydrochloride,CI-1033 dihydrochloride,PD-183805 dihydrochlori
Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities.
价 格:¥电议型 号:T2501产 地:美洲
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T2623PD 98059PD 98059
PD98059 is a non-ATP competitive MEK inhibitor (IC50: 2/50 μM for MEK1/MEK2).
价 格:¥电议型 号:T2623产 地:美洲
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T48052-Hydroxypyridine2-Hydroxypyridine
2-Hydroxypyridine is the catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.
价 格:¥电议型 号:T4805产 地:美洲
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T5049NVP-BSK805NVP-BSK805,BSK 805,NVP-BSK805 2HCl
NVP-BSK805 is an ATP-competitive JAK2 inhibitor.
价 格:¥电议型 号:T5049产 地:美洲
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T5805Norarecoline hydrochlorideNorarecoline hydrochloride
Norarecoline hydrochloride is a muscarinic agonist.
价 格:¥电议型 号:T5805产 地:美洲
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T5S18055,7-Dihydroxychromone5,7-Dihydroxychromone,5,7-Dihydroxy-4H-Chromen-4-One,
1. 5,7-Dihydroxychromone isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating
价 格:¥电议型 号:T5S1805产 地:美洲
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T6136CanertinibCanertinib,PD-183805,CI-1033
Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
价 格:¥电议型 号:T6136产 地:美洲
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T8674SR33805;化合物SR33805SR33805
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)
价 格:¥电议型 号:T8674产 地:中国大陆
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T83805Rp-Adenosine-5’-O-(1-thiodiphosphate) sodium;化合物 Rp-Adenosine-5’-O-(1-thiodiphosphate) sodiumRp-ADP-
Rp-Adenosine-5´-O-(1-thiodiphosphate) (Rp-ADP-α-S), a sulfur-containing isomer of the nucleotide derivative ADP-α-S, acts as an inhibitor of phosphorylase kinase with an inhibition constant (Ki) of 0.53 ?M. This compound also induces aggregation in isolated human platelets with an effective concentration (EC50) of 20 ?M and promotes relaxation in guinea pig taenia coli that has been precontracted with carbamoylcholine, with an EC50 of 58.9 ?M.
价 格:¥电议型 号:T83805产 地:中国大陆
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T82805Butaprost free acid;化合物 Butaprost free acidButaprost free acid
(R)-Butaprost (free acid) is a prostaglandin E2 (PGE2) analog exhibiting high EP2 receptor subtype selectivity, commonly used to delineate EP receptor expression in human and animal tissues and cells. In 1986, Gardiner induced significant confusion regarding its structure by incorrectly identifying the selective C-16 epimer as (R)-butaprost (refer to the British Journal of Pharmacology, page 46, as TR 4979, and notes). By removing the methyl ester and restoring the native carboxylic acid at C-1,
价 格:¥电议型 号:T82805产 地:中国大陆
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T81805Mevonlerbart;化合物 MevonlerbartMevonlerbart
Mevlonerbart, an IgG4κ antibody, specifically targets human Felcat allergen 1, an allergen protein.
价 格:¥电议型 号:T81805产 地:中国大陆
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T80805WAY-607695;化合物 WAY-607695WAY-607695
WAY-607695 is a potential 5-HT1A receptor agonist.
价 格:¥电议型 号:T80805产 地:中国大陆
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T80599Dectrekumab;德屈库单抗QAX576;QAX576
Dectrekumab (QAX576), a humanized monoclonal antibody targeting IL-13, significantly reduces intraepithelial esophageal eosinophil counts and normalizes dysregulated esophageal disease-related transcripts in Eosinophilic esophagitis (EoE), offering sustained benefits. It is valuable for inflammation and immunology research [1].
价 格:¥电议型 号:T80599产 地:中国大陆
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T80598Davoceticept;化合物 DavoceticeptCD80 vIgD-Fc|||ALPN-202;CD80 vIgD-Fc|||ALPN-202
Davoceticept (ALPN-202; CD80 vIgD-Fc), a monoclonal antibody that targets CTLA-4, is comprised of the (1-107) fragment of CD80 fused to the IGHG1 Fc domain through a peptidyl linker. It is commonly produced in CHO (Chinese Hamster Ovary) cells [1].
价 格:¥电议型 号:T80598产 地:中国大陆
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T80597Dafsolimab;化合物 DafsolimabSPV-T3a;SPV-T3a
Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is utilized in research pertaining to graft-versus-host disease (GVHD) [1].
价 格:¥电议型 号:T80597产 地:中国大陆
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T80596Coprelotamab;化合物 CoprelotamabGB-221;GB-221
Coprelotamab (GB-221) is an IgG-κ monoclonal antibody that targets EGFR2, frequently produced in CHO DG44 (Chinese Hamster Ovary) cells [1].
价 格:¥电议型 号:T80596产 地:中国大陆
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T80595Conbercept;化合物 ConberceptKH902;KH902
Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDR, linked to the Fc fragment of IGHG1. This monoclonal antibody targets VEGF receptors and is designed for therapeutic use. Conbercept [1].
价 格:¥电议型 号:T80595产 地:中国大陆
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T80594Ormutivimab;化合物 OrmutivimabrhRIG|||NM57;rhRIG|||NM57
Ormutivimab (rhRIG), a recombinant human monoclonal antibody designed to target the rabies virus, effectively neutralizes various strains and demonstrates strong efficacy as a post-exposure prophylaxis (PEP) treatment in model studies [1] [2].
价 格:¥电议型 号:T80594产 地:中国大陆