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T79255UPCDC30766;化合物 UPCDC30766UPCDC30766
UPCDC30766, a potent allosteric inhibitor of p97, exhibits an IC50 of 12 nM and is applicable for colon cancer research [1].
价 格:¥电议型 号:T79255产 地:中国大陆
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T79239PCSK9-IN-19;化合物 PCSK9-IN-19PCSK9-IN-19
PCSK9-IN-19 (Compound 1), a PCSK9 inhibitor, is utilized in researching the treatment of high LDL-cholesterol levels and the prevention of coronary artery disease [1].
价 格:¥电议型 号:T79239产 地:中国大陆
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T79054TRPC3/6-IN-2;化合物 TRPC3/6-IN-2TRPC3/6-IN-2
TRPC3/6-IN-2 is a potent inhibitor of TRPC3 and TRPC6, exhibiting IC50 values of 16 nM for TRPC3 and 29.8 nM for TRPC6, respectively [1].
价 格:¥电议型 号:T79054产 地:中国大陆
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T79053PCSK9-IN-17;化合物 PCSK9-IN-17PCSK9-IN-17
PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.
价 格:¥电议型 号:T79053产 地:中国大陆
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T79052PCSK9-IN-16;化合物 PCSK9-IN-16PCSK9-IN-16
PCSK9-IN-16, holds potential for research into hypercholesterolemia and other cardiovascular diseases [1].
价 格:¥电议型 号:T79052产 地:中国大陆
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T79051PCSK9-IN-15;化合物 PCSK9-IN-15PCSK9-IN-15
PCSK9-IN-15 (compound 5) is a potent inhibitor of proprotein convertase subtilisin/kexin 9 (PCSK9, K D <200 nM) that plays a crucial role in cholesterol metabolism by regulating blood levels of low-density lipoprotein cholesterol (LDL-C). This compound is useful for researching cholesterol-lowering therapies and dyslipidemia [1].
价 格:¥电议型 号:T79051产 地:中国大陆
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T79030PCSK9-IN-14;化合物 PCSK9-IN-14PCSK9-IN-14
PCSK9-IN-14, also known as compound Ia-8, is a potent inhibitor of PCSK9 [1].
价 格:¥电议型 号:T79030产 地:中国大陆
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T78624OPC-163493;化合物 OPC-163493OPC-163493
OPC-163493 is an orally active, liver-targeted mitochondrial uncoupling agent that diminishes Δψ (delta psi) and mitochondrial ROS (reactive oxygen species) production. This compound demonstrates antidiabetic properties and cardiovascular benefits, including lowering blood pressure, prolonging survival, and enhancing renal function in a rat model of stroke/hypertension [1].
价 格:¥电议型 号:T78624产 地:中国大陆
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T78605CpCDPK1/TgCDPK1-IN-1;CpCDPK1/TgCDPK1抑制剂1CpCDPK1/TgCDPK1-IN-1
CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections and cryptosporidiosis.
价 格:¥电议型 号:T78605产 地:中国大陆
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T78377CTP;化合物 CTPCTP
CTP, a cardiac targeting peptide, efficiently and specifically transduces cardiomyocytes in vitro and heart tissue in mouse models. It has potential for the targeted delivery of therapeutic peptides, proteins, and nucleic acids to the heart [1].
价 格:¥电议型 号:T78377产 地:中国大陆
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T78351Phosphoenolpyruvate carboxylase;化合物 Phosphoenolpyruvate carboxylasePEPC;PEPC
Phosphoenolpyruvate carboxylase (PEPC) is an enzyme that irreversibly catalyzes the conversion of phosphoenolpyruvate and bicarbonate to oxaloacetate and inorganic phosphorus in the presence of Mg2+. It is essential for the primary assimilation of CO(2) in Crassulacean acid metabolism plants and significantly influences the diurnal rhythm of plant metabolism [1] [2].
价 格:¥电议型 号:T78351产 地:中国大陆
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T78331Epcoritamab;化合物 EpcoritamabGEN3013;GEN3013
Epcoritamab (GEN3013) is a bispecific IgG1 antibody that redirects T-cells toward CD3×CD20-positive tumor cells, inducing potent T-cell-mediated cytotoxicity against B-cell non-Hodgkin lymphoma (NHL) cell lines [1].
价 格:¥电议型 号:T78331产 地:中国大陆
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T782284-Chloro-L-phenylalanine;4-氯-L-苯基丙氨酸L-4-Chlorophenylalanine|||L-PCPA;L-4-Chlorophenylalanine|||L-PCP
4-Chloro-L-phenylalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis.4-Chloro-L-phenylalanine is also a non-specific antagonist of tryptophan hydroxylase (TPH1 and TPH2).
价 格:¥电议型 号:T78228产 地:中国大陆
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T78069RPR132595A hydrochloride;化合物 RPR132595A hydrochlorideNPC hydrochloride;NPC hydrochloride
RPR132595A (NPC) hydrochloride, an active metabolite of CPT-11, is produced via cytochrome P-450 3A4 (CYP3A4) metabolism and is ultimately eliminated via urinary excretion [1].
价 格:¥电议型 号:T78069产 地:中国大陆
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T78037Hepcidin-1 (mouse) TFA;化合物 Hepcidin-1 (mouse) TFAHepcidin-1 (mouse) TFA
Hepcidin-1 (mouse) TFA, an endogenous peptide hormone, regulates iron homeostasis by upregulating mRNA levels of TRAP, cathepsin K, and MMP-9, enhancing TRAP-5b protein secretion, and downregulating FPN1 protein levels, thereby increasing intracellular iron. It also promotes osteoclast differentiation [1].
价 格:¥电议型 号:T78037产 地:中国大陆
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T77916(S,R,S)-AHPC-Boc;化合物 (S,R,S)-AHPC-BocVH032-Boc;VH032-Boc
(S,R,S)-AHPC-Boc (VH032-Boc) serves as a ligand for the von Hippel-Lindau (VHL) protein recruitment in PROTAC technology [1].
价 格:¥电议型 号:T77916产 地:中国大陆
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T7773DPPC;二棕榈酸磷脂酰胆碱1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOL|||129Y83;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO
DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.
价 格:¥电议型 号:T7773产 地:中国大陆
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T77614DpC;化合物DpCDpC
DPC is an antitumor compound that inhibits cancer cell proliferation with an IC50 of 0.007-0.096 μM.DPC is involved in a variety of anticancer therapies and can be used in cancer research.
价 格:¥电议型 号:T77614产 地:中国大陆
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T7752(S,R,S)-AHPC-Me;化合物(S,R,S)-AHPC-MeVHL ligand 2|||E3 ligase Ligand 1A;VHL ligand 2|||E3 ligase Ligand
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
价 格:¥电议型 号:T7752产 地:中国大陆
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T77407Ensituximab;恩妥昔单抗NPC-1C|||NEO-102|||NEO-101;NPC-1C|||NEO-102|||NEO-101
Ensituximab (NEO-102) is a quasi-selective IgG1 monoclonal antibody against the MUC5AC variant with anti-tumour activity that inhibits colorectal and pancreatic cancer.
价 格:¥电议型 号:T77407产 地:中国大陆