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  • T72025PCSK9-IN-10；化合物PCSK9-IN-10PCSK9-IN-10

    PCSK9-IN-10, a potent and orally active inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), exhibits a half-maximal inhibitory concentration (IC50) of 6.4 ?M. By enhancing the expression of Low-Density Lipoprotein Receptor (LDLR) protein and reducing PCSK9 expression, PCSK9-IN-10 effectively decreases atherosclerosis progression. This compound holds promise for hyperlipidemia research applications.

    价 格：￥电议型 号：T72025产 地：中国大陆

  • T71654APcK110；化合物 APcK110APcK110

    APcK110 is a novel Kit inhibitor . APcK110 inhibits proliferation of the mastocytosis cell line HMC1.2 and the SCF-responsive cell line OCI/AML3 in a dose-dependent manner . APcK110 is a more potent inhibitor of OCI/AML3 proliferation than the clinically used Kit inhibitors imatinib and dasatinib and at least as potent as cytarabine. APcK110 inhibits the phosphorylation of Kit, Stat3, Stat5, and Akt in a dose-dependent fashion, showing activity of APcK110 on Kit and its downstream signaling path

    价 格：￥电议型 号：T71654产 地：中国大陆

  • T71538AMPCP；化合物 AMPCPAMPCP

    AMPCP is an Ecto-5´-nucleotidase (CD73) inhibitor.

    价 格：￥电议型 号：T71538产 地：中国大陆

  • T71439Opc 4392；化合物 Opc 4392Opc 4392

    Opc 4392 is an agonist of presynaptic dopamine D(2) receptor.

    价 格：￥电议型 号：T71439产 地：中国大陆

  • T71323Npc 12626；化合物 Npc 12626Npc 12626

    Npc 12626 is a N-methyl-D-aspartate receptor antagonist; NPC 17742, the (2R,4R,5S)-isomer, is the most potent isomer in the mixture NPC 12626.

    价 格：￥电议型 号：T71323产 地：中国大陆

  • T71252PC-046；化合物 PC-046PC-046

    PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory activity in a variety of tumor types in vitro, and efficacy in SCID mice was shown in human tumor xenografts of MV-4-11 acute myeloid leukemia, MM.1S multiple myeloma, and DU-145 prostate cancer. Pharmacokinetic studies demonstrated relatively high oral bioavailability (71 %) with di

    价 格：￥电议型 号：T71252产 地：中国大陆

  • T71226Opc 15161；化合物 Opc 15161Opc 15161

    Opc 15161 is a degradation product of OPC-15160 and superoxide inhibitor.

    价 格：￥电议型 号：T71226产 地：中国大陆

  • T71127Ipconazole [ISO]；化合物 Ipconazole [ISO]Ipconazole [ISO]

    Ipconazole is a member of the class of cyclopentanols carrying 1,2,4-triazol-1-ylmethyl, 4-chlorobenzyl and isopropyl substituents at positions 1, 2 and 5 respectively. Used to control a range of seed diseases in rice, vegetables and other, mainly non-food, crops. It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal agrochemical. It is a member of cyclopentanols, a member of monochlorobenzenes, a member of triazoles, a tertiary alcohol, a conazole fungicide

    价 格：￥电议型 号：T71127产 地：中国大陆

  • T710542-PCCA；化合物 2-PCCA2-PCCA

    2-PCCA is a GPR88 agonist.

    价 格：￥电议型 号：T71054产 地：中国大陆

  • T7105Zinc phthalocyanine酞菁锌酞菁锌|||ZnPc

    Zinc phthalocyanine (ZnPc) are photosensitive,is commonly applied in industry (catalysts, photoconductors) and biomedical (photodynamic therapy).

    价 格：￥电议型 号：T7105产 地：中国大陆

  • T71024NPC-16731；化合物 NPC-16731NPC-16731

    NPC-16731 is a Bradykinin antagonist.

    价 格：￥电议型 号：T71024产 地：中国大陆

  • T70789VPC03090；化合物 VPC03090VPC03090

    VPC03090 is a Sphingosine-1-Phosphate Receptor Inhibitor. VPC03090 is an analog of FTY-720, acts as antagonist for S1PR1 and S1PR3. VPC03090-P, converted from VPC03090 through the phosphorylation by SK-2, causes a reduction in tumor growth in mice with mammary cancer, and its oral bioavailability is determined to be 30 hours.

    价 格：￥电议型 号：T70789产 地：中国大陆

  • T70590NPC-14695；化合物 NPC-14695NPC-14695

    NPC-14695 is a smooth muscle-selective muscarinic antagonist with bronchodilating activity.

    价 格：￥电议型 号：T70590产 地：中国大陆

  • T70576NPC 17731；化合物 NPC 17731NPC 17731

    NPC 17731 is a bradykinin receptor antagonist.

    价 格：￥电议型 号：T70576产 地：中国大陆

  • T70574NPC 17761；化合物 NPC 17761NPC 17761

    NPC 17761 is a bradykinin receptor antagonist.

    价 格：￥电议型 号：T70574产 地：中国大陆

  • T70387CCCTP；化合物 CCCTPCCCTP

    CCCTP is a potent inhibitor of the 11β-HSD-1 enzyme with reduced pregnane-X receptor (PXR) transactivation activity.

    价 格：￥电议型 号：T70387产 地：中国大陆

  • T70291PCC0208018；化合物 PCC0208018PCC0208018

    PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) binding and not directly affecting tumor cell viability in vitro.

    价 格：￥电议型 号：T70291产 地：中国大陆

  • T70193APC-366 HCl；化合物 APC-366 HClAPC-366 HCl

    APC-366 is a selective inhibitor of the mast cell tryptase that inhibits tryptase-induced histamine release from human tonsil and lung cells.

    价 格：￥电议型 号：T70193产 地：中国大陆

  • T70187NPC-18915；化合物 NPC-18915NPC-18915

    NPC-18915 is a benzofuran compound, inhibitor of neutophil activation.

    价 格：￥电议型 号：T70187产 地：中国大陆

  • T69982VPC-16606；化合物 VPC-16606VPC-16606

    VPC-16606 is a potent and selective inhibitor of ERα-dependent cell growth and gene expression. VPC-16606 prevents the interaction between ERα-LBD and SRC-3 fusion proteins in a dose-dependent manner.

    价 格：￥电议型 号：T69982产 地：中国大陆

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