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  • T64339Apcin A HCL；APCIN A 盐酸盐Apcin A HCL

    Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) inhibitor. Apcin-A HCL interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A HCL can be used to synthesize the PROTAC CP5V [1].

    价 格：￥电议型 号：T64339产 地：中国大陆

  • T63788PCLX-001；化合物PCLX-001PCLX-001

    PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstrates anti-tumor effects and effectively inhibits the early signaling of B-cell receptor (BCR). Consequently, PCLX-001 is a valuable tool for researching B-cell malignancies [1] [2].

    价 格：￥电议型 号：T63788产 地：中国大陆

  • T6325PCI-34051N-羟基-1-(4-甲氧基苄基)-1H-吲哚-6-甲酰胺N-羟基-1-(4-甲氧基苄基)-1H-吲哚-6-甲酰胺|||PCI 34051

    PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).

    价 格：￥电议型 号：T6325产 地：中国大陆

  • T62711OPC-14523 hydrochloride；OPC-14523 盐酸盐VPI 013 hydrochloride；VPI 013 hydrochloride

    OPC-14523 hydrochloride (VPI 013 hydrochloride) is an orally active and potent sigma and 5-HT1A receptor agonist with antidepressant activity for the study of neurological disorders.

    价 格：￥电议型 号：T62711产 地：中国大陆

  • T62589TRPC5-IN-4；化合物 TRPC5-IN-4TRPC5-IN-4

    TRPC5-IN-4, a potent and safe TRPC inhibitor, exhibits IC50 values of 14.07 nM and 65 nM for TRPC5 and TRPC4, respectively, indicating high efficacy. It does not cause damage to liver and kidney cellular components, making it suitable for chronic kidney disease (CKD) research [1].

    价 格：￥电议型 号：T62589产 地：中国大陆

  • T62552Ozanimod hydrochloride；Ozanimod 盐酸盐BMS-986374 hydrochloride|||RPC-1063 hydrochloride；BMS-986374 hydr

    Ozanimod hydrochloride (RPC-1063 hydrochloride) is an orally available, selective and potent sphingosine 1-phosphate (S1P) receptor modulator that shows high affinity for S1P1 and S1P5.Ozanimod has potential anticancer activity and can be used in the study of multiple sclerosis (MS), ulcerative multiple sclerosis (UMS), and other diseases. (MS), ulcerative colitis, coronavirus infections and myelodysplasia.

    价 格：￥电议型 号：T62552产 地：中国大陆

  • T62272TRPC6-IN-3；化合物 TRPC6-IN-3TRPC6-IN-3

    TRPC6-IN-3 (compound 17) is an orally active inhibitor of the transient receptor potential C6 ion channel (TRPC6), which regulates intracellular calcium concentration and also regulates cation fluxes including calcium and sodium ions to modulate membrane potential.

    价 格：￥电议型 号：T62272产 地：中国大陆

  • T62201TRPC6-IN-2；化合物 TRPC6-IN-2TRPC6-IN-2

    TRPC6-IN-2 is a TRPC protein inhibitor, specifically inhibiting TRPC6 protein.

    价 格：￥电议型 号：T62201产 地：中国大陆

  • T62133TRPC5 modulator-1；化合物 TRPC5 modulator-1TRPC5 modulator-1

    TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator (IC50<1 nM) that can be used to study neuropsychiatric disorders.

    价 格：￥电议型 号：T62133产 地：中国大陆

  • T62088TRPC5-IN-2；化合物 TRPC5-IN-2TRPC5-IN-2

    TRPC5-IN-2 is a potent inhibitor of TRPC5.

    价 格：￥电议型 号：T62088产 地：中国大陆

  • T62067TRPC5-IN-3；化合物 TRPC5-IN-3TRPC5-IN-3

    TRPC5-IN-3 is a potent TRPC5 inhibitor (IC50= 10.75 nM).

    价 格：￥电议型 号：T62067产 地：中国大陆

  • T61653VPC-13789；化合物 VPC-13789VPC-13789

    VPC-13789 is a highly potent, selective, and orally bioavailable antiandrogen compound that shows promise for studying and developing therapeutics for castration-resistant prostate cancer (CRPC). In LNCaP cells, VPC-13789 effectively inhibits the transcriptional activity of the androgen receptor (AR) with an IC50 value of 0.19 μM [1].

    价 格：￥电议型 号：T61653产 地：中国大陆

  • T61407TRPC3/6-IN-1；化合物 TRPC3/6-IN-1TRPC3/6-IN-1

    TRPC3/6-IN-1 is a highly potent and selective inhibitor that specifically blocks the activity of the canonical transient receptor channels TRPC3 and TRPC6. It exhibits a significant blocking potency against the human isoforms hTRPC3 and hTRPC6, with IC50 values of 1260 nM and 500 nM, respectively. This compound, TRPC3/6-IN-1, is particularly valuable for conducting research on chronic models of heart failure [1].

    价 格：￥电议型 号：T61407产 地：中国大陆

  • T61274PC190723；化合物 PC190723PC190723

    PC190723 (Compound 2), an inhibitor of the FtsZ bacterial cell division protein, demonstrates potent efficacy with an IC50 value of 55 ng/ml. Additionally, it showcases notable anti-staphylococcal activity, characterized by Minimum Inhibitory Concentration (MIC) values of 1 μg/ml against both Methicillin-Sensitive Staphylococcus aureus (MSSA) and Methicillin-Resistant Staphylococcus aureus (MRSA) [1].

    价 格：￥电议型 号：T61274产 地：中国大陆

  • T61144Hepcidin antagonist-1；Hepcidin 拮抗剂1Hepcidin antagonist-1

    Hepcidin antagonist-1 is an iron-modulating antagonist.Hepcidin antagonist-1 can be used to study metabolic disorders such as iron-deficiency diseases and anemia.

    价 格：￥电议型 号：T61144产 地：中国大陆

  • T60981TRPC4/5-IN-1；化合物 TRPC4/5-IN-1TRPC4/5-IN-1

    TRPC4/5-IN-1 can be used for the research of skin inflammatory diseases and proteinuric kidney diseases. TRPC4/5-IN-1 is a potent inhibitor of TRP channel 5/4 (TRPC5/4) with IC50 values of 0.54 μM and 2.06 μM, respectively. [1].

    价 格：￥电议型 号：T60981产 地：中国大陆

  • T60764PCSK9 modulator-4；化合物 PCSK9 modulator-4PCSK9 modulator-4

    PCSK9 modulator-4 (Compound 21) can be used in hyperlipidemia research that is a potent PCSK9 modulator (EC 50 = 0.15 nM). PCSK9 is a lowering low-density lipoprotein cholesterol (LDL-C) target that is recently validated [1].

    价 格：￥电议型 号：T60764产 地：中国大陆

  • T60762PCAF-IN-1；化合物 PCAF-IN-1PCAF-IN-1

    PCAF-IN-1 is a antitumor agents used in tumor treatment research. PCAF-IN-1 is a highly selective inhibitor of PCAF [1].

    价 格：￥电议型 号：T60762产 地：中国大陆

  • T60646PCSK9 modulator-3；化合物 PCSK9 modulator-3PCSK9 modulator-3

    PCSK9 modulator-3 (Compound 13) is a potent PCSK9 modulator with an EC 50 value of 2.46 nM that has the potential in the hyperlipidemia research. PCSK9 is a recently proved target for lowering low-density lipoprotein cholesterol (LDL-C) [1].

    价 格：￥电议型 号：T60646产 地：中国大陆

  • T60541PCSK9 modulator-2；化合物 PCSK9 modulator-2PCSK9 modulator-2

    PCSK9 modulator-2 (Compound 1) is a potent PCSK9 modulator (EC 50 = 202 nM) that has the potential to be used in hyperlipidemia research. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a recently validated therapeutic target for lowering low-density lipoprotein cholesterol (LDL-C) [1].

    价 格：￥电议型 号：T60541产 地：中国大陆

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