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T68470ASB-16165；化合物 ASB-16165ASB-16165
ASB-16165 is a phosphodiesterase 7A inhibitor that impairs proliferation of keratinocytes in vitro and in vivo. Inhibitors of PDE7A including ASB16165 might be useful for the treatment of psoriasis.
价 格：￥电议型 号：T68470产 地：中国大陆
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T68161LTienoxolol FA；替诺洛尔甲酸盐Tienoxolol FA (90055-97-3 Free base)；Tienoxolol FA (90055-97-3 Free base)
Tienoxolol FA is a small molecule beta-adrenergic receptor antagonist used in the treatment of cardiovascular disease and in the study of hypertension and cardiac machine ischemia.
价 格：￥电议型 号：T68161L产 地：中国大陆
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T66161Amiloxate；化合物 AmiloxateAmiloxate
Amiloxate is a useful organic compound for research related to life sciences and the catalog number is T66161.
价 格：￥电议型 号：T66161产 地：中国大陆
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T65161Ethyl trichloroacetate；化合物 Ethyl trichloroacetateEthyl trichloroacetate
Ethyl trichloroacetate is a useful organic compound for research related to life sciences. The catalog number is T65161 and the CAS number is 515-84-4.
价 格：￥电议型 号：T65161产 地：中国大陆
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T64161XIAP degrader-1；化合物 XIAP degrader-1XIAP degrader-1
XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).
价 格：￥电议型 号：T64161产 地：中国大陆
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T63942WNY1613；化合物 WNY1613WNY1613
WNY1613 is a potent and selective PI3Kδ inhibitor with a piperazinone-containing purine scaffold.WNY1613 has anti-NHL effects in vitro and in vivo.WNY1613 inhibits phosphorylation of the downstream component of PI3K in NHL cell lines and induces apoptosis in cancer cells.
价 格：￥电议型 号：T63942产 地：中国大陆
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T6347Ki16198；化合物Ki16198Ki16198
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6.
价 格：￥电议型 号：T6347产 地：中国大陆
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T63161EGFR/HER2/CDK9-IN-3；化合物 EGFR/HER2/CDK9-IN-3EGFR/HER2/CDK9-IN-3
EGFR/HER2/CDK9-IN-3 (Compound 10) is a potent inhibitor of EGFR (IC50:191.08 nM), HER2 (IC50:132.65 nM), and CDK9 (IC50:113.98 nM). EGFR/HER2/CDK9-IN-3 showed significant anti-tumor effects.
价 格：￥电议型 号：T63161产 地：中国大陆
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T63010ZXH-1-161；化合物 ZXH-1-161ZXH-1-161
ZXH-1-161 is a potent regulator of cereblon (CRBN) that acts on wild-type MM1.S cells (IC50: 39 μM). ZXH-1-161 selectively degrades GSPT1. ZXH-1-161 can be used to study multiple myeloma.
价 格：￥电议型 号：T63010产 地：中国大陆
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T62860YM-341619；化合物 YM-341619YM-341619
YM-341619 (AS1617612) is a potent, orally active STAT6 inhibitor (IC50: 0.70 nM). YM-341619 inhibits IL-4-induced Th2 differentiation in mouse splenic T cells with an IC50 value of 0.28 nM, but does not affect Th1 cell differentiation. YM-341619 is a compound with potential for use in the study of allergic diseases, such as allergic asthma.
价 格：￥电议型 号：T62860产 地：中国大陆
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T62721CPI-1612；化合物 CPI-1612CPI-1612
CPI-1612 is a potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor that acts on EP300 HAT (IC50: 8.1 nM). CPI-1612 exhibits anticancer effects.
价 格：￥电议型 号：T62721产 地：中国大陆
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T62161eIF4A3-IN-4；化合物 eIF4A3-IN-4eIF4A3-IN-4
eIF4A3-IN-4 is a novel inhibitor of eIF4A (IC50: 8.6 μM).
价 格：￥电议型 号：T62161产 地：中国大陆
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T61619XN methyl pyrazole；化合物 XN methyl pyrazoleXN methyl pyrazole
XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1].
价 格：￥电议型 号：T61619产 地：中国大陆
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T61618PI3K-IN-38；PI3K抑制剂38PI3K-IN-38
PI3K-IN-38 is an orally available and potent PI3K inhibitor with an IC50 value of 0.541 ?M for PI3K-α. PI3K-IN-38 exhibits anticancer and anti-inflammatory activity and inhibits tumor growth in vivo.
价 格：￥电议型 号：T61618产 地：中国大陆
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T61617Hcyb1；化合物 Hcyb1Hcyb1
Hcyb1 is a potent and specific inhibitor of phosphodiesterase 2 (PDE2). It exhibits a high degree of selectivity for inhibiting PDE2A with an IC50 value of 0.57 μM. In addition, Hcyb1 displays over 250-fold selectivity against other recombinant members of the PDE family. Moreover, its pharmacological actions include neuroprotective and antidepressant-like effects, which are believed to be mediated through the cAMP/cGMP-CREB-BDNF signaling pathway [1].
价 格：￥电议型 号：T61617产 地：中国大陆
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T61616Antitumor agent-38；化合物 Antitumor agent-38Antitumor agent-38
Antitumor agent-38 is a highly effective antitumor compound that exhibits antiproliferative activity towards cancer cells. It induces cell cycle arrest specifically at the late S and G2/M phase, while not impeding microtubule formation or altering cell morphology [1].
价 格：￥电议型 号：T61616产 地：中国大陆
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T61615Myt1-IN-2；化合物 Myt1-IN-2Myt1-IN-2
Myt1-IN-2, a highly potent Myt1 inhibitor, exhibits remarkable anticancer properties with an IC50 value below 10 nM (WO2021195782A1; compound 28) [1].
价 格：￥电议型 号：T61615产 地：中国大陆
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T61614HIF-2α-IN-5；化合物 HIF-2α-IN-5HIF-2α-IN-5
HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of < 50 nM [1].
价 格：￥电议型 号：T61614产 地：中国大陆
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T61613SARS-CoV-2-IN-17；化合物 SARS-CoV-2-IN-17SARS-CoV-2-IN-17
SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to NPro with a low Kd value of 7.82 μM, highlighting its potency as a NPro ligand [1].
价 格：￥电议型 号：T61613产 地：中国大陆
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T61612ATX inhibitor 15；化合物 ATX inhibitor 15ATX inhibitor 15
ATX inhibitor 15 (compound 30) is an indole-based carbamate derivative with a strong inhibitory effect on autotaxin (ATX), demonstrated by an IC50 of 2.17 nM. Additionally, ATX inhibitor 15 effectively inhibits ATX activity in vivo and suppresses the expression of pro-fibrotic genes. Furthermore, ATX inhibitor 15 exhibits protective effects in lung fibrosis induced by Bleomycin in mice [1].
价 格：￥电议型 号：T61612产 地：中国大陆
