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T61611α-Synuclein inhibitor 4;化合物 α-Synuclein inhibitor 4α-Synuclein inhibitor 4
α-Synuclein inhibitor 4 (compound 3gh) is a highly effective and blood-brain barrier-permeable inhibitor of α-Synuclein aggregation. It displays potent activity, with an IC50 value of 0.98 μM, and exhibits a remarkable inhibition ratio of 91.2% at a concentration of 30 μM [1].
价 格:¥电议型 号:T61611产 地:中国大陆
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T61610NPEC-caged-LY379268;化合物 NPEC-caged-LY379268NPEC-caged-LY379268
NPEC-caged-LY379268 is a type II mGluR agonist [1].
价 格:¥电议型 号:T61610产 地:中国大陆
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T6161Tubastatin A Hydrochloride;化合物Tubastatin A HClTSA HCl|||Tubastatin A HCl;TSA HCl|||Tubastatin A HCl
Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM). It has selectivity (>1000-fold) against all other isozymes except HDAC8 (>57-fold).
价 格:¥电议型 号:T6161产 地:中国大陆
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T61161HIF-1α-IN-3;化合物 HIF-1α-IN-3HIF-1α-IN-3
HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].
价 格:¥电议型 号:T61161产 地:中国大陆
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T60478BTX161;化合物 BTX161BTX161
BTX161 is a Thalidomide analogue. BTX161 is a potent CKIα degrader. In human AML cells, BTX161 mediates the CKIα degradation better than Lenalidomide as well as activates DNA damage response (DDR) and p53, and also stabilizes the p53 antagonist MDM2[1].
价 格:¥电议型 号:T60478产 地:中国大陆
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T60252HSK16149;化合物 HSK16149HSK16149
HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.
价 格:¥电议型 号:T60252产 地:中国大陆
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T60161CP-289;化合物CP-289CP-289
CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
价 格:¥电议型 号:T60161产 地:中国大陆
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T5852Canthaxanthin;斑蝥黄all-trans-Canthaxanthin|||E 161g;all-trans-Canthaxanthin|||E 161g|||角黄素|||斑蝥黄
Canthaxanthin (E 161g) is a red-orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi.
价 格:¥电议型 号:T5852产 地:中国大陆
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T5161Gadodiamide;钆双铵Gadodiamide
Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.
价 格:¥电议型 号:T5161产 地:中国大陆
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T4S1619L-Hyoscyamine sulfate;L-莨菪碱硫酸盐Hyoscyamine sulfate hydrate|||Levsin Sulfate|||Hyoscyamine Sulphate;Hy
L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointes
价 格:¥电议型 号:T4S1619产 地:中国大陆
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T4S1616Sanggenon D;桑根酮 DSanggenone D;Sanggenone D
Sanggenon D (Sanggenone D), a small molecule compound from Morus alba Bark, is a GABA(A) receptor modulator with antioxidant and antibacterial activity, inhibits breast cancer cell proliferation, and inhibits the growth of Staphylococcus aureus by modulating the fatty acid biosynthesis system.
价 格:¥电议型 号:T4S1616产 地:中国大陆
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T4S1615Sanggenon C;桑根酮 CSanggenone C;桑根酮C|||桑根酮 C|||Sanggenone C
1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.
价 格:¥电议型 号:T4S1615产 地:中国大陆
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T40161(Rac)-5-Hydroxymethyl Tolterodine hydrochloride;(Rac)-5-Hydroxymethyl Tolterodine hydrochloride(Rac)
(Rac)-5-Hydroxymethyl Tolterodine hydrochloride, also known as (Rac)-Desfesoterodine hydrochloride, is an active metabolite of Tolterodine that functions as a mAChR antagonist. It exhibits significant affinity (K i values) for M1, M2, M3, M4, and M5 receptors, with values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM, respectively. This compound is commonly employed in research related to overactive bladder conditions.
价 格:¥电议型 号:T40161产 地:中国大陆
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T3S1612kuwanon G;桑黄酮 GMoracenin B|||Kuwanone G;桑黄酮G|||Moracenin B|||桑黄酮 G|||Kuwanone G
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has anti-inflammatory activity, it can attenuate atherosclerosis through inhibiting foam cell formation and inflammatory response. 3. Kuwanon G is a potent inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B. 4. Kuwanon G shows acetylcholinesterase (AChE) and butyry
价 格:¥电议型 号:T3S1612产 地:中国大陆
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T39161Ro60-0175;化合物Ro60-0175Ro60-0175;Ro60-0175
Ro60-0175 a selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumarate salt. It has a role as a 5-hydroxytryptamine 2B receptor agonist and a 5-hydroxytryptamine 2C receptor agonist.
价 格:¥电议型 号:T39161产 地:中国大陆
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T38544Fasitibant chloride;Fasitibant chlorideMEN16132 free base|||Fasitibant chloride;MEN16132 free base||
Fasitibant chloride (MEN16132 free base) is a powerful and specific nonpeptide antagonist of the bradykinin B2 receptor (B2R). This compound effectively reduces joint pain and mitigates joint edema in a rat model of Carrageenan-induced arthritis.
价 格:¥电议型 号:T38544产 地:中国大陆
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T38161STING Agonist C11;STING Agonist C11STING Agonist C11;STING Agonist C11
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o´nyong-nyong, Mayaro, and Ross River virus
价 格:¥电议型 号:T38161产 地:中国大陆
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T371618-hydroxy Amoxapine;8-hydroxy Amoxapine8-hydroxy Amoxapine
8-hydroxy Amoxapine is a metabolite of the tetracyclic antidepressant amoxapine .1,2
价 格:¥电议型 号:T37161产 地:中国大陆
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T361618-iso Prostaglandin E2 isopropyl ester;8-iso Prostaglandin E2 isopropyl ester8-iso Prostaglandin E2
8-iso PGE2 isopropyl ester is a more lipophilic form of the free acid, 8-iso PGE2. Prostaglandin esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of prostaglandins show greatly diminished agonist activity in vitro compared to the parent free acids.
价 格:¥电议型 号:T36161产 地:中国大陆
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T36090S14161S14161S-14161|||S14161
S14161 has a wide range of applications in life science related research.
价 格:¥电议型 号:T36090产 地:中国大陆