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T62052AMPK activator 6;化合物 AMPK activator 6AMPK activator 6
AMPK activator 6 (Compound GC) activates the AMPK pathway and reduces lipid content in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase of total cholesterol (TC), low-density lipoprotein-C (LDL-C), triglyceride (TG), and other biochemical indices in blood serum. AMPK activator 6 has research value in non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome .
价 格:¥电议型 号:T62052产 地:中国大陆
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T62051(R)-(+)-Dimethindene maleate;化合物 (R)-(+)-Dimethindene maleate(R)-(+)-Dimethindene maleate
(R)-(+)-Dimethindene maleate is an orally active H 1 -receptor blocker.
价 格:¥电议型 号:T62051产 地:中国大陆
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T62050Orexin receptor antagonist 4;化合物 Orexin receptor antagonist 4Orexin receptor antagonist 4
Orexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist. Orexin receptor antagonist 4 shows IC50 of 4.27 nM and 295 nM for OX2R and OX1R, respectively.
价 格:¥电议型 号:T62050产 地:中国大陆
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T6205AT7519;化合物AT7519AT7519
AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.
价 格:¥电议型 号:T6205产 地:中国大陆
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T61205Nrf2/HO-1 activator 1;化合物 Nrf2/HO-1 activator 1Nrf2/HO-1 activator 1
Nrf2/HO-1 activator 1 (Compound 24) is a potent neuroprotective agent with significant antioxidant activities, specifically targeting Nrf2/HO-1. It is particularly useful in Parkinson´s disease (PD) research, illustrating its potential in therapeutic applications [1].
价 格:¥电议型 号:T61205产 地:中国大陆
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T60205Antibacterial agent 171;抗菌剂 171Antibacterial agent 171
(2S)-4-biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide is a LpxC inhibitor with IC50 >95.2 nM.
价 格:¥电议型 号:T60205产 地:中国大陆
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T5S2205Sibiricaxanthone B;西伯利亚远志呫吨酮BSibiricaxanthone B
Sibiricaxanthone B is an oxygen-containing xanthone isolated from Polygala tenuifolia.
价 格:¥电议型 号:T5S2205产 地:中国大陆
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T5S2059Glaucine;海罌粟鹼Glaucine
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 inhibitory activity, attenuating IκBα and NF-κB activities.
价 格:¥电议型 号:T5S2059产 地:中国大陆
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T5642Tegatrabetan;化合物BC2059BC2059;BC2059
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
价 格:¥电议型 号:T5642产 地:中国大陆
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T5486RU.521;化合物RU320521RU320521;RU320521
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
价 格:¥电议型 号:T5486产 地:中国大陆
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T4532LLinrodostat mesylate;化合物 T4532LONO-7701|||BMS-986205|||ONO 7701|||BMS986205|||BMS 986205;ONO-7701|||
Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs).
价 格:¥电议型 号:T4532L产 地:中国大陆
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T4532Linrodostat;化合物LinrodostatBMS-986205;BMS-986205
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
价 格:¥电议型 号:T4532产 地:中国大陆
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T4205AG-494;化合物AG 494Tyrphostin AG-494|||AG 494|||Tyrphostin B48;Tyrphostin AG-494|||AG 494|||Tyrphostin
AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.
价 格:¥电议型 号:T4205产 地:中国大陆
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T40195CRA-2059;CRA-2059CRA-2059
CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.
价 格:¥电议型 号:T40195产 地:中国大陆
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T3S0205β-Hederin;β-常春藤素Beta-Hederin;Beta-Hederin|||β-常春藤素
1. β-Hederin has antileishmanial activity. 2. β-Hederin has apoptotic effect on breast cancer cells, it could be a promising candidate for chemotherapy of breast cancer.
价 格:¥电议型 号:T3S0205产 地:中国大陆
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T39493VemircopanVemircopanACH0145228|||ACH-5228|||ALXN2050
Vemircopan is a complement factor D inhibitor.
价 格:¥电议型 号:T39493产 地:中国大陆
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T39205HKSOX-1;HKSOX-1HKSOX-1
HKSOX-1 is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 exhibits excellent selectivity and sensitivity towards superoxide anion radical.
价 格:¥电议型 号:T39205产 地:中国大陆
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T38776LP-922056;化合物LP-922056LP-922056
LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
价 格:¥电议型 号:T38776产 地:中国大陆
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T38350TAS 205;TAS 205TAS 205
TAS 205 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS; IC50= 55.8 nM).1It is selective for H-PGDS over lipocalin-type PGDS (L-PGDS) at 100 μM, as well as over enzyme and receptor panels at 10 μM. TAS 205 inhibits production of prostaglandin D2induced by A23187 in KU812 human and RBL-2H3 rat basophils with IC50values of 78.3 and 181.3 nM, respectively. It inhibits ovalbumin-induced nasal lavage fluid eosinophil infiltration and late-phase nasal obstruction in an ovalbumin-sens
价 格:¥电议型 号:T38350产 地:中国大陆
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T38052CRA-2059 TFA;CRA-2059 TFACRA-2059 TFA
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
价 格:¥电议型 号:T38052产 地:中国大陆