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T15490HO-PEG15-OH;化合物 T15490HO-PEG15-OH
HO-PEG15-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T15490产 地:中国大陆
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T14920CE-224535;化合物CE-224535PF-04905428;PF-04905428
CE-224535 (PF-04905428) is a selective antagonist of P2X7 receptor. CE-224535 can be used in disease-modifying antirheumatic studies.
价 格:¥电议型 号:T14920产 地:中国大陆
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T14909CCX140;化合物CCX140CCX140-B;3-三氟甲基-4-氯-N-[2-[7H-吡咯并[2,3-D]嘧啶-4-羰基]-5-甲基-3-吡啶基]苯磺酰胺|||CCX140-B
CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.
价 格:¥电议型 号:T14909产 地:中国大陆
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T14908CCT367766;化合物CCT367766CCT367766
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low conc
价 格:¥电议型 号:T14908产 地:中国大陆
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T14907CCT251545;化合物CCT251545CCT251545
CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).
价 格:¥电议型 号:T14907产 地:中国大陆
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T14906CCT251455;化合物 T14906CCT251455
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
价 格:¥电议型 号:T14906产 地:中国大陆
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T14905CCT251236;化合物 CCT251236CCT251236
CCT251236 is a cell-based phenotypic high-throughput screening (HTS) chemical probe developed to screen for inhibitors of the HSF1 stress pathway.CCT251236 exhibits antimyeloma activity and inhibits HSF1.
价 格:¥电议型 号:T14905产 地:中国大陆
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T14904CCT244747;化合物 T14904CCT244747
CCT244747 is a CHK1 inhibitor (IC50: 7.7 nM) and also abrogates G2 checkpoint (IC50: 29 nM).
价 格:¥电议型 号:T14904产 地:中国大陆
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T14903CCT129957;化合物CCT129957CCT129957
CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
价 格:¥电议型 号:T14903产 地:中国大陆
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T14902CCT020312;化合物CCT020312CCT020312
CCT020312 is a selective activator of EIF2AK3 and PERK. CCT020312 durably inhibits cell proliferation and elicits the phosphorylation of EIF2A.
价 格:¥电议型 号:T14902产 地:中国大陆
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T14901CCT-251921;化合物CCT-251921CCT-251921
CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).
价 格:¥电议型 号:T14901产 地:中国大陆
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T14900CCR2-RA-[R]化合物CCR2-RA-[R](5R)-4-乙酰基-1-(4-氯-2-氟苯基)-5-环己基-1,5-二氢-3-羟基-2H-吡咯-2-酮
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).
价 格:¥电议型 号:T14900产 地:中国大陆
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T1490Gestodene;孕二烯酮SHB 331|||WL 70;SHB 331|||WL 70|||孕二烯酮
Gestodene (WL 70) is a progestogen hormonal contraceptive.
价 格:¥电议型 号:T1490产 地:中国大陆
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T1484LPerindopril erbumine;培哚普利叔丁胺S9490-3|||Perindopril tert-butylamine salt;培哚普利叔丁胺|||培哚普利叔丁胺盐|||S9490-3|
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril erbumine (S9490-3) is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited a
价 格:¥电议型 号:T1484L产 地:中国大陆
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T14490Talipexole dihydrochloride;盐酸他利克索Domnin|||B-HT 920 dihydrochloride;Domnin|||盐酸他利克索|||B-HT 920 dihydr
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, respectively. It displays antiParkinsonian activity.
价 格:¥电议型 号:T14490产 地:中国大陆
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T14327AS1949490;化合物AS1949490AS1949490
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.
价 格:¥电议型 号:T14327产 地:中国大陆
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T1349025,26-Dihydroxyvitamin D3;化合物 T1349025,26-Dihydroxycholecalciferol;25,26-Dihydroxycholecalciferol
25,26-Dihydroxyvitamin D3 is a metabolite of vitamin D3 with intestinal calcium transport activity.
价 格:¥电议型 号:T13490产 地:中国大陆
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T13352Wy 49051;化合物Wy 49051Wy-49051;Wy-49051
Wy 49051 is an orally active antagonist of H1 receptor(IC50 of 44 nM).
价 格:¥电议型 号:T13352产 地:中国大陆
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T1314901,3-Dihydroxy-10-methylacridone;化合物 1,3-Dihydroxy-10-methylacridone1,3-Dihydroxy-10-methylacridone
1,3-Dihydroxy-10-methylacridone is a useful organic compound for research related to life sciences and the catalog number is T131490.
价 格:¥电议型 号:T131490产 地:中国大陆
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T1304901-(3,4-Dihydroxyphenyl)-1-propanol, 3?,4?-Di-Me et;化合物 1-(3,4-Dihydroxyphenyl)-1-propanol, 3?,4?-Di-
1-(3,4-Dihydroxyphenyl)-1-propanol, 3?,4?-Di-Me et is a useful organic compound for research related to life sciences and the catalog number is T130490.
价 格:¥电议型 号:T130490产 地:中国大陆