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T4903Heptadecanoic acid;十七烷酸Inhibitor|||disease|||heart|||prediabetes|||carcinomas|||cell|||lung|||Heptad
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% of milk fat and 0.83% of ruminant meat fat. The content of heptadecanoic acid in the subcutaneous adipose tissue of humans appears to be a good biological marker of long-term milk fat intake in free-living individuals in populations with high consumption of dairy product
价 格:¥电议型 号:T4903产 地:中国大陆
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T4902Isotrifoliin;异槲皮苷Isoquercetin|||Isoquercitroside;Isoquercetin|||Isoquercitroside|||槲皮素-3-氧葡萄糖甙
Isotrifoliin (Isoquercitroside)n is an effective antioxidant and an eosinophilic inflammation suppressor.
价 格:¥电议型 号:T4902产 地:中国大陆
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T4900(±)-Methyl Jasmonate;甲基茉莉酮酸酯(±)-Jasmonic Acid methyl ester|||Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclo
Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester)induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. More specifically, methyl jasmonate inhibits hexokinase that is bound to mitochondria. As hexokinase is overexpressed in cancer cells and contributes to cancer cell growth and survival, methyl jasmonate´s disruption of mitochondrial hexokinase activity selectively targets, an
价 格:¥电议型 号:T4900产 地:中国大陆
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T4490PF-01247324;化合物PF01247324PF-01247324
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
价 格:¥电议型 号:T4490产 地:中国大陆
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T4136Lapachol;黄钟花醌Bethabarra wood|||CI75490|||Greenhartin|||Tecomin;Bethabarra wood|||CI75490|||黄钟花醌|||Gr
Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
价 格:¥电议型 号:T4136产 地:中国大陆
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T40490Phenylalanylalanine;苯并氨酰丙氨酸H-Phe-Ala-OH;H-Phe-Ala-OH|||苯并氨酰丙氨酸
Phenylalanylalanine (H-Phe-Ala-OH) (H-Phe-Ala-OH) is a dipeptide resulting from the fusion of phenylalanine and alanine. It is formed during incomplete protein digestion or catabolism [1].
价 格:¥电议型 号:T40490产 地:中国大陆
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T39490AclimostatAclimostatZGN-1061|||Aclimostat
Aclimostat (ZGN-1061) is a highly potent inhibitor of the MetAP2 enzyme that demonstrates promising efficacy and safety profiles in preclinical trials. In a mouse model of obesity and insulin resistance, ZGN-1061 exhibits comparable weight loss efficacy to beloranib, while also improving metabolic parameters. Additionally, ZGN-1061 induces consistent changes in gene transcription in HepG2 cells, further supporting its positive pharmacological effects.
价 格:¥电议型 号:T39490产 地:中国大陆
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T38490ONX 0801 trisodiumONX 0801 trisodiumIdetrexedtrisodium|||BGC 945 trisodium|||CB300945trisodium
ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.
价 格:¥电议型 号:T38490产 地:中国大陆
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T3749011(R)-HETE;11(R)-HETE11(R)-HETE
11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S. purpuratus, and the fresh water hydra, H. vulgaris. The biological activity of 11(R)-HETE relates to oocyte maturation and tentacle regeneration, respectively, in these two species. 11(R)-HETE is also produced when aspirin-treated recombinant COX-2 is incubated with arachidonic acid. Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC retention times to published results.
价 格:¥电议型 号:T37490产 地:中国大陆
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T36490AZT triphosphate TEA;AZT triphosphate TEAAZT triphosphate TEA
AZT triphosphate TFA (3´-Azido-3´-deoxythymidine-5´-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TFA also inhibits the DNA polymerase of HBV. AZT triphosphate TFA activates the mitochondria-mediated apoptosis pathway[1][2][3].
价 格:¥电议型 号:T36490产 地:中国大陆
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T354902-Amino-5-bromo-6-chloropyrazine;2-Amino-5-bromo-6-chloropyrazine2-Amino-5-bromo-6-chloropyrazine
2-Amino-5-bromo-6-chloropyrazine is a heterocyclic building block.1,2It has been used in the synthesis of Akt inhibitors.
价 格:¥电议型 号:T35490产 地:中国大陆
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T3512S49076 HCl;化合物S49076 HClS-49076 Hydrochloride;S-49076 Hydrochloride
S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 HCl potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in vivo. In cell models, S49076 HCl inhibited the proliferation of MET- and FGFR2-dependent gastric cancer cells blocked MET-driven migration of lung carcinoma cells, and inhibited colony formation of hepatocarcinoma cells expressing FGFR1/2 and AXL. In tumor xenograft models, a goo
价 格:¥电议型 号:T3512产 地:中国大陆
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T35083VUF 4904;化合物 T35083VUF-4904|||VUF4904;VUF-4904|||VUF4904
VUF 4904 is a bioactive chemical.
价 格:¥电议型 号:T35083产 地:中国大陆
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T34908TP-422;化合物 T34908TP422;TP422
TP-422 is a negative control for TP-238.
价 格:¥电议型 号:T34908产 地:中国大陆
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T34907TP-238;化合物 T34907TP 238;TP 238
TP-238, a potent and selective dual CECR2/BPTF probe, exhibits IC50 values of 30 nM and 350 nM, respectively. Additionally, it inhibits BRD9 with a pIC50 of 5.9, demonstrating lesser activity against another 338 kinases [1] [2].
价 格:¥电议型 号:T34907产 地:中国大陆
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T34905Totrombopag;化合物TotrombopagSB559448|||SB 559448|||SB-559448|||LGD-4665|||Synonym 2|||LGD 4665|||LGD46
Totrombopag (SB559448) is a candidate compound for action on RSV polymerase.
价 格:¥电议型 号:T34905产 地:中国大陆
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T34904Torcitabine;化合物 T34904NV-02C|||L-dC|||NV 02C|||L-Deoxycytidine;NV-02C|||L-dC|||NV 02C|||L-Deoxycytid
Torcitabine is useful against the hepatitis B virus.
价 格:¥电议型 号:T34904产 地:中国大陆
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T34903TO-PRO3 iodide;化合物 T34903TOPRO3 iodide|||TO-PRO3 iodide salt;TOPRO3 iodide|||TO-PRO3 iodide salt
TO-PRO3 iodide is a nucleic acid stain that can stain the nucleus of cells in different states, including living, early apoptotic, and necrotic cells.
价 格:¥电议型 号:T34903产 地:中国大陆
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T34902Tonoquil;化合物 T34902Veritan HCl|||Veritan hydrochloride;Veritan HCl|||Veritan hydrochloride
Tonoquil is a bioactive chemical.
价 格:¥电议型 号:T34902产 地:中国大陆