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TN52631-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one1[2,4D
Xanthohumol, prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus. Xanthohumol is effective against HIV-1 and might serve as an interesting lead compound. It may represent a novel chemotherapeutic agent for HIV-1 infection.
价 格:¥电议型 号:TN5263产 地:中国大陆
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T7263SMS2-IN-2Inhibitor,SMS-2-IN-2,SMS2 IN 2,SMS2IN2,inhibit
SMS2-IN-2 is a potent, selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, (IC50s of 100 and 56 μM for SMS2 and SMS1, respectively). SMS2-IN-2 has anti-chronic inflammatory activity.
价 格:¥电议型 号:T7263产 地:中国大陆
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T9636DalpiciclibMCF7,BT-474/T,Cyclin dependent kinase,Eca 109,MCF7/TR,and KYSE-510 ESCC,SHR6390,Inhibitor
Dalpiciclib is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4?nM and 9.9?nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
价 格:¥电议型 号:T9636产 地:中国大陆
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T10929LD-3263 hydrochloride
D-3263 hydrochloride is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
价 格:¥电议型 号:T10929L产 地:中国大陆
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T6763XevinapantSM 406,SM406,Xevinapant,AT-406,oral,inhibit,Debio 1143,ovarian,IAP,degradation,Smac,AT 406
AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
价 格:¥电议型 号:T6763产 地:中国大陆
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TQ0311GSK163090Dopamine Receptor,5-HT1A,GSK163090,Inhibitor,5-hydroxytryptamine Receptor,antidepressant,an
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
价 格:¥电议型 号:TQ0311产 地:中国大陆
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T7633SenktideSenktide,Inhibitor,inhibit,Tachykinin receptor,NK receptor,Neurokinin Receptor
Senktide is an agonist of tachykinin NK3 receptor.
价 格:¥电议型 号:T7633产 地:中国大陆
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T7369LGemigliptin Tartrate(911637-19-9 free base)type,Gemigliptin,products,mellitus,peptidase-4,Gemiglipti
Gemigliptin tartrate is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties.
价 格:¥电议型 号:T7369L产 地:中国大陆
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T6463DeoxyarbutinTyrosinase,inhibit,Deoxyarbutin,Inhibitor
DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.
价 格:¥电议型 号:T6463产 地:中国大陆
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T8863VK-II-36Calcium Channel,VKII36,Ca channels,Ca2+ channels,Inhibitor,inhibit,VK II 36
VK-II-36, a carvedilol analog, suppresses sarcoplasmic reticulum (SR) Ca(2+) release but does not block the β-receptor.
价 格:¥电议型 号:T8863产 地:中国大陆
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T8639Phenibut (hydrochloride)Inhibitor,anxiogenic,Phenibut,inhibit,PEA,neuropsychotropic,Phenibut (hydroc
Phenibut (hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine
价 格:¥电议型 号:T8639产 地:中国大陆
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TP1363LNeurokinin B acetate(86933-75-7 free base)Neurokinin B acetate(86933757 free base),Neurokinin B acet
Neurokinin B acetate is the acetate form of Neurokinin B, which belongs to the tachykinin family. Neurokinin binds to neurokinin receptor 1 (NK1R), nk2r and NK3R, and mediates its biological effects.
价 格:¥电议型 号:TP1363L产 地:中国大陆
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T6385Amoxicillin SodiumAmoxycillin,cell wall,Inhibitor,Amoxicillin Sodium,Antibiotic,inhibit,polypeptides
Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
价 格:¥电议型 号:T6385产 地:中国大陆
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TP1572GR-73632Neurokinin Receptor,NK receptor,Tachykinin receptor,GR73632,inhibit,Inhibitor,GR-73632,GR 73
Potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens).
价 格:¥电议型 号:TP1572产 地:中国大陆
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T23638Adibendan
Adibendan is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.
价 格:¥电议型 号:T23638产 地:中国大陆
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T63190Cudetaxestat
Cudetaxestat is a potent inhibitor of orally active autotaxin.
价 格:¥电议型 号:T63190产 地:中国大陆
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T7638NPPBNPPB,Cl? Channels,Chloride Channel,inhibit,Inhibitor
NPPB is a chloride channel blocker with IC50 of 80 nM .
价 格:¥电议型 号:T7638产 地:中国大陆
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T6393ARQ 621motor,inhibit,cell,ARQ 621,division,protein,Inhibitor,microtubule,ARQ621,Kinesin,Anti-tumor,E
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
价 格:¥电议型 号:T6393产 地:中国大陆
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TN5634Aureusidinanti-inflammatory effects,LOX,Lipoxygenase,antioxidant,inhibit,Aureusidin,Reactive Oxygen
Aureusidin shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.
价 格:¥电议型 号:TN5634产 地:中国大陆
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T8632Anthracene-9-carboxylic acidAnthracene9carboxylic acid,Anthracene 9 carboxylic acid
Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.
价 格:¥电议型 号:T8632产 地:中国大陆