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  • T6313Go 6983Goe 6983

    Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ, PKCδ and PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.

    价 格:¥电议型 号:T6313产 地:中国大陆

  • T6311BafetinibINNO-406;NS-187;巴氟替尼

    Bafetinib (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.

    价 格:¥电议型 号:T6311产 地:中国大陆

  • T6310GW3965 hydrochlorideGW3965 HCl

    GW3965 HCl is an effective and specific LXR agonist for hLXRα/β (EC50: 190/30 nM).

    价 格:¥电议型 号:T6310产 地:中国大陆

  • T6309AZ960AZ 960

    AZ 960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).

    价 格:¥电议型 号:T6309产 地:中国大陆

  • T6308StatticSTAT3 Inhibitor V

    Stattic is a small molecule inhibitor of STAT3. It selectively inhibits STAT3 activation, dimerization, and nuclear translocation (IC50: 5.1 μM).

    价 格:¥电议型 号:T6308产 地:中国大陆

  • T6307Lubiprostone芦比前列酮;鲁比前列酮;RU-0211;SPI-0211

    Lubiprostone, an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.

    价 格:¥电议型 号:T6307产 地:中国大陆

  • T6306ErteberelLY500307

    LY500307 is a potent, selective estrogen receptor β agonist with EC50 of 0.66 nM, 32-fold selectivity against estrogen receptor α. Phase 2.

    价 格:¥电议型 号:T6306产 地:中国大陆

  • T6305SNX2112SNX 2112;PF 04928473;SNX-2112

    SNX-2112 is an orally active Hsp90 inhibitor, with a Kd of 16 nM.

    价 格:¥电议型 号:T6305产 地:中国大陆

  • T6304AT7867

    AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.

    价 格:¥电议型 号:T6304产 地:中国大陆

  • T6303LCCT128930 hydrochlorideCCT128930 hydrochloride(885499-61-6 Free base)

    CCT128930 hydrochloride is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50:

    价 格:¥电议型 号:T6303L产 地:中国大陆

  • T6303CCT128930

    CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.

    价 格:¥电议型 号:T6303产 地:中国大陆

  • T6302LonafarnibSch66336;Sarasar;氯那法尼

    Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).

    价 格:¥电议型 号:T6302产 地:中国大陆

  • T6301Tosedostat托舍多特;CHR-2797

    CHR-2797 is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. CHR-2797 is converted intracellularly into a poorly membrane-permeable active metabolite (CHR-79888) which inhibits the M1 family of a

    价 格:¥电议型 号:T6301产 地:中国大陆

  • T6300DegrasynWP1130

    Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits Bcr/Abl, which is a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT).

    价 格:¥电议型 号:T6300产 地:中国大陆

  • T6263Safflower-yellow

    Safflower yellow is extracted from the flowers of the plant safflower (Carthamus tinctorius) and as the traditional Chinese medicine it has been extensively used for the treatment of cardio cerebrovascular diseases.

    价 格:¥电议型 号:T6263产 地:中国大陆

  • T6249AvagacestatBMS-708163

    Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.

    价 格:¥电议型 号:T6249产 地:中国大陆

  • T6241Quetiapine hemifumarate富马酸喹硫平;ICI-204636;Quetiapine Fumarate

    Quetiapine Fumarate, an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.

    价 格:¥电议型 号:T6241产 地:中国大陆

  • T6215Abiraterone Acetate乙酸阿比特龙酯;CB7630;Zytiga

    Abiraterone acetate is an androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER.

    价 格:¥电议型 号:T6215产 地:中国大陆

  • T6191Tasisulam他司磺胺;LY573636

    Tasisulam is an apoptosis inducer and an antitumor agent via the intrinsic pathway.

    价 格:¥电议型 号:T6191产 地:中国大陆

  • T6163Salirasib沙利雷塞;法尼基硫代水杨酸;FTS;Farnesyl Thiosalicylic Acid;S-Farnesylthiosalicylic acid

    Salirasib(Ki=2.6 μM), an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor, inhibits Ras methylation with potential antineoplastic activity.

    价 格:¥电议型 号:T6163产 地:中国大陆

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