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  • T37753Aureusimine B;3-(1-甲基乙基)-6-(苯甲基)-2(1H)-吡嗪酮Aureusimine B

    Aureusimine B, a Calpain inhibitor, is produced by Staphylococcus aureus biofilms and could be a potential biomarker for S. aureus biofilm-based infections.

    价 格:¥电议型 号:T37753产 地:中国大陆

  • T37539Amycolatopsin A;Amycolatopsin AAmycolatopsin A

    Amycolatopsin A is a macrolide polyketide originally isolated fromAmycolatopsisthat has antimycobacterial and anticancer activities.1It is active againstM. bovisandM. tuberculosis(IC50s = 0.4 and 4.4 μM, respectively) but notB. subtilis,S. aureus,E. coli, orP. aeruginosa(IC50s = >30 μM for all). Amycolatopsin A is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 0.08 and 1.2 μM, respectively).

    价 格:¥电议型 号:T37539产 地:中国大陆

  • T37538Amifostine thiol;Amifostine thiolAmifostine thiol

    Amifostine thiol (WR-1065), the active metabolite of cytoprotector Amifostine, serves as a cytoprotective agent possessing radioprotective properties. It activates p53 via a JNK-dependent signaling pathway[1][2][3].

    价 格:¥电议型 号:T37538产 地:中国大陆

  • T37537Carbazomycin D;Carbazomycin DCarbazomycin D

    Carbazomycin D is a bacterial metabolite that has been found inStreptomycesand has diverse biological activities.1,2It is active against the fungiT. asteroidesandT. mentagrophytes(MIC = 100 μg/ml for both) and the bacteriumM. tuberculosis(IC50= 25 μg/ml). Carbazomycin D is cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 21.3, 33.2, 12.9, and 34.3 μg/ml, respectively).2

    价 格:¥电议型 号:T37537产 地:中国大陆

  • T37536Carbazomycin A;Carbazomycin ACarbazomycin A

    Carbazomycin A is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities.1,2It is active againstS. aureus,T. asteroides, andT. mentagrophytes(MIC = 12.5 μg/ml for all), as well as the plant pathogenic fungusP. oryzae(MIC = 25 μg/ml). Carbazomycin A is cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 26.2, 30.1, 18.4, and 32.6 μg/ml, respectively).2

    价 格:¥电议型 号:T37536产 地:中国大陆

  • T37535Camrelizumab;卡瑞利珠单抗SHR-1210;SHR-1210

    Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up to 3 nM and is inhibitory to PD-1/PD-L1 with an IC50 of 0.70 nM.Camrelizumab exhibits anti-tumor activity and is well tolerated in the study cancers including NSC-LC, ESCC, Hodgkin´s lymphoma and advanced HCC.

    价 格:¥电议型 号:T37535产 地:中国大陆

  • T37534DMPAC-CholDMPAC-CholDMPACChol|||DMPAC Chol

    DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 μg/ml.

    价 格:¥电议型 号:T37534产 地:中国大陆

  • T37533DOPALDOPALDOPAL

    DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate α-synuclein, an event associated with Parkinson´s disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL

    价 格:¥电议型 号:T37533产 地:中国大陆

  • T37532Docosahexaenoyl Glycine;Docosahexaenoyl GlycineDocosahexaenoyl Glycine

    The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.

    价 格:¥电议型 号:T37532产 地:中国大陆

  • T37531Glycerophosphorylethanolamine (sodium salt);Glycerophosphorylethanolamine (sodium salt)Glycerophosph

    Glycerophosphorylethanolamine is an active phosphodiester metabolite of phosphatidylethanolamine.1,2It promotes aggregation of amyloid-β (1-40) (Aβ40)in vitro, and levels of glycerophosphorylethanolamine are elevated in postmortem brains isolated from patients with Alzheimer’s disease.

    价 格:¥电议型 号:T37531产 地:中国大陆

  • T37530Glycerophospho-N-Arachidonoyl Ethanolamine;Glycerophospho-N-Arachidonoyl EthanolamineGlycerophospho-

    N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. The different types of NAE can be derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-arachidonoyl ethanolamine is the precursor of arachidonoyl ethanolamide (AEA), also known as anandamide. AEA is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. It inhibit

    价 格:¥电议型 号:T37530产 地:中国大陆

  • T3753Sinapinic Acid;芥子酸Sinapic acid|||Synapoic acid;Sinapic acid|||芥子酸|||Synapoic acid

    Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I/R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoprot

    价 格:¥电议型 号:T3753产 地:中国大陆

  • T36753DMT-dC(ac) Phosphoramidite;DMT-dC(ac) PhosphoramiditeDMT-dC(ac) Phosphoramidite

    DMT-dC(ac) Phosphoramidite is a phosphoramidite monomer that has been modified for use in oligonucleotide synthesis.

    价 格:¥电议型 号:T36753产 地:中国大陆

  • T36702CAY10753;CAY10753CAY10753

    CAY10753 is an inhibitor of tankyrase 2 (TNKS2; IC50= 0.3 nM).1It is selective for TNKS2 over TNKS1 (IC50= 6.1 nM), as well as poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 89.6 and 37.8 nM, respectively). CAY10753 inhibits proliferation of DLD-1 colorectal cancer cells when used at a concentration of 1 μM.

    价 格:¥电议型 号:T36702产 地:中国大陆

  • T35753Z-Phe-Tyr(tBu)-diazomethylketone;Z-Phe-Tyr(tBu)-diazomethylketoneZ-Phe-Tyr(tBu)-diazomethylketone

    Irreversible cathepsin L inhibitor which is ca 10´000 times more effective in inactivating cathepsin L than cathepsin S.

    价 格:¥电议型 号:T35753产 地:中国大陆

  • T35169Xenyhexenic acid;化合物 T35169SCR157|||CV 57733|||CV-57733|||CV57733|||CV 57533;SCR157|||CV 57733|||CV-

    Xenyhexenic acid is a biochemical.

    价 格:¥电议型 号:T35169产 地:中国大陆

  • T34977U 78753E;化合物 T34977U-78753E|||DCDPP;U-78753E|||DCDPP

    U 78753E is a biochemical.

    价 格:¥电议型 号:T34977产 地:中国大陆

  • T34753Suxamethonium bromide;化合物 T34753L.T. 1|||370 I.S.|||Brevidil M;L.T. 1|||370 I.S.|||Brevidil M

    Suxamethonium bromide can be used to cause short-term paralysis as part of general anesthesia.

    价 格:¥电议型 号:T34753产 地:中国大陆

  • T33753NSC265473;化合物 T33753NSC-265473|||NSC-305458|||NSC305458|||NSC 265473|||NSC 305458;NSC-265473|||NSC-3

    NSC265473 is an ABCG2 substrate.

    价 格:¥电议型 号:T33753产 地:中国大陆

  • T32753Limazocic;化合物 T32753SA-3443|||SA3443|||SA 3443;SA-3443|||SA3443|||SA 3443

    Limazocic is a cyclic disulfide with hepatoprotective effects.

    价 格:¥电议型 号:T32753产 地:中国大陆

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