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  • T63779RmlA-IN-2;化合物 RmlA-IN-2RmlA-IN-2

    RmlA-IN-2 is a potent inhibitor of 1-phosphoglucose thymidyltransferase (RmlA) (IC50: 0.303 μM).RmlA-IN-2 affects the monosaccharide l-rhamnose biosynthetic pathway and affects bacterial cell wall permeability.

    价 格:¥电议型 号:T63779产 地:中国大陆

  • T62779PI3K-IN-35;化合物 PI3K-IN-35PI3K-IN-35

    PI3K-IN-35 (Compound 6l) is a highly selective inhibitor of PI3K, acting on PI3K-α (IC50: 13.98 μM), PI3K-β (IC50: 7.22 μM) and PI3K-δ (IC50: 10.94 μM). PI3K-IN-35 blocks the cell cycle in G2/M phase and induces apoptosis. PI3K-IN-35 can be used to study leukaemia.

    价 格:¥电议型 号:T62779产 地:中国大陆

  • T61779STAT3-IN-9;化合物 STAT3-IN-9STAT3-IN-9

    STAT3-IN-9, a potent inhibitor of STAT3 activation at Tyr705, exhibits no impact on the phosphorylation of STAT1 at Tyr 701. Additionally, this compound efficiently induces apoptosis and cell cycle arrest specifically at the G2/M phase [1].

    价 格:¥电议型 号:T61779产 地:中国大陆

  • T6122CEP-33779;化合物CEP33779CEP33779;CEP33779

    CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.

    价 格:¥电议型 号:T6122产 地:中国大陆

  • T60779CD73-IN-13;化合物 CD73-IN-13CD73-IN-13

    CD73-IN-13 is able to be used in a medicament preparing for tumor-related diseases. CD73-IN-13 is a potent inhibitor of CD73 which is closely associated with tumor growth, angiogenesis and metastasis [1].

    价 格:¥电议型 号:T60779产 地:中国大陆

  • T5779MOSLOFLAVONE;5-羟基-6,7-二甲氧基黄酮MOSLOFLAVONE

    MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.

    价 格:¥电议型 号:T5779产 地:中国大陆

  • T5148Atosiban acetate醋酸阿托西班RW22164|||Atosiban acetate (90779-69-4 free base)|||RWJ22164|||醋酸阿托西班

    Atosiban acetate (RW22164) is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban acetate (RW22164) inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. As a result, there is reduced release of intracellular, stored calcium from the sarcoplasmic reticulum of myometrial cells, and reduced influx of Ca2+ from the extracellular space through

    价 格:¥电议型 号:T5148产 地:中国大陆

  • T4S0779D-tetrahydropalmatine;右旋四氢巴马汀D-tetrahydropalmatine

    D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.

    价 格:¥电议型 号:T4S0779产 地:中国大陆

  • T47794-Methylcatechol;3,4-二羟基甲苯p-Methylcatechol|||Homocatechol|||4-methylbenzene-1,2-diol|||3,4-Dihydroxy

    4-Methylcatechol (3,4-Dihydroxytoluene) is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-Methylcatechol (3,4-Dihydroxytoluene) is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.

    价 格:¥电议型 号:T4779产 地:中国大陆

  • T40779Benzyl-PEG9-THP;Benzyl-PEG9-THPBenzyl-PEG9-THP;Benzyl-PEG9-THP

    Benzyl-PEG9-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T40779产 地:中国大陆

  • T39779BMT-297376;BMT-297376BMT-297376

    BMT-297376, the optimized Linrodostat, is a potent IDO1 inhibitor.

    价 格:¥电议型 号:T39779产 地:中国大陆

  • T39248PF-06426779;PF-06426779PF-06426779

    PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM.

    价 格:¥电议型 号:T39248产 地:中国大陆

  • T39191LDSTYSLSSTLTLSK acetate;化合物DSTYSLSSTLTLSK acetateDSTYSLSSTLTLSK acetate (177792-42-6 Free base);DSTYS

    DSTYSLSSTLTLSK acetate is a human generic peptide that can be used for the quantitative detection of infliximab.

    价 格:¥电议型 号:T39191L产 地:中国大陆

  • T38779NS-102;NS-102NS-102

    NS-102 is a powerful and selective antagonist of the kainate receptor (GluK2), as well as a potent antagonist of the GluR6/7 receptor.

    价 格:¥电议型 号:T38779产 地:中国大陆

  • T38716SAR247799;SAR247799SAR247799|||S1P1 agonist 3;SAR247799|||S1P1 agonist 3

    SAR247799 (S1P1 agonist 3) is an orally-active, selective G-protein-biased agonist for the sphingosine-1 phosphate receptor-1 (S1P1). It demonstrates EC50 values ranging from 12.6 to 493 nM in S1P1-overexpressing cells and HUVECs. SAR247799 holds promise as a valuable tool for investigating endothelial protection, particularly in the context of type-2 diabetes and metabolic syndrome[4].

    价 格:¥电议型 号:T38716产 地:中国大陆

  • T37799PF 04671536 hydrochloridePF 04671536 hydrochloridePF 04671536 hydrochloride

    Potent and selective PDE8B/8A inhibitor ( IC50 values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.

    价 格:¥电议型 号:T37799产 地:中国大陆

  • T37798PetromyzonolPetromyzonolPetromyzonol

    Petromyzonol is a tetrahydroxy stearol which serves as the primary spawning pheromone in adult sea lamprey. It is produced in the bile of sea lamprey larvae from the bile acid precursor allocholic acid. While the adult sea lamprey is relatively insensitive to petromyzonol itself, the C-24 sulfate ester (petromyzonol sulfate) is a pheromone and a spawning chemoattractant which can be detected at very low concentrations by lamprey olfactory chemoreceptors. Petromyzonol, petromyzonol sulfate, and a

    价 格:¥电议型 号:T37798产 地:中国大陆

  • T37797Coumarin-Quinone Conjugate;Coumarin-Quinone ConjugateCoumarin-Quinone Conjugate

    Coumarin-quinone conjugate is a fluorescent substrate for NADH:ubiquinone oxidoreductases.1It is comprised of a coumarin fluorophore conjugated to a ubiquinone analog that can be reduced by NADH:ubiquinone oxidoreductases. It has been used to measure the kinetic parameters of apoptosis-inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1).

    价 格:¥电议型 号:T37797产 地:中国大陆

  • T37796Voriconazole N-oxide;Voriconazole N-oxideVoriconazole N-oxide

    Voriconazole N-oxide is a major metabolite of the triazole antifungal voriconazole . It is formed via oxidation of voriconazole by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C19.

    价 格:¥电议型 号:T37796产 地:中国大陆

  • T37795Retrobradykinin;RetrobradykininRetrobradykinin

    Bradykinin analog nonapeptide. Reverse sequence of Bradykinin. Exhibits no significant kinin activity. Can be used as a negative control.

    价 格:¥电议型 号:T37795产 地:中国大陆

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