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T37794Rec 15/2615 (hydrochloride);Rec 15/2615 (hydrochloride)Rec 15/2615 (hydrochloride)
Rec 15/2615 is an antagonist of α1B-adrenergic receptors (α1B-ARs; Ki = 0.45 nM for the recombinant human receptor).1 It selectively inhibits α1B-ARs over α1A-, α1D-, and α1L-ARs (Kis = 7.59, 10.23, and 49 nM, respectively). Rec 15/2615 inhibits norepinephrine-induced contractions of isolated rabbit prostate and urethral strips (Kis = 100 and 316.2 nM, respectively), as well as reduces norepinephrine-induced contractions of chloroethylclonidine-precontracted isolated rabbit aortic rings (Ki = 50
价 格:¥电议型 号:T37794产 地:中国大陆
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T37793A2B receptor antagonist 2;化合物A2B receptor antagonist 2A2B receptor antagonist 2;A2B receptor antagon
A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).
价 格:¥电议型 号:T37793产 地:中国大陆
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T37792A2A receptor antagonist 1;化合物A2A receptor antagonist 1CPI-444 analog|||A2A receptor antagonist 1;CPI
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.
价 格:¥电议型 号:T37792产 地:中国大陆
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T37791A-971432;A-971432A-971432
A-971432 is a sphingosine-1-phosphate receptor 5 (S1P5) agonist that is selective for S1P5 over S1P1 and S1P3 (IC50s = 0.006, 0.362, and >10 µM, respectively). It inhibits forskolin-induced cAMP production in CHO cells expressing S1P5 (EC50 = 4.1 nM). A-971432 (1 µM) increases electrical resistance of hCMEC/D3 cells in an in vitro blood-brain barrier model, indicating enhanced barrier integrity, and attenuates blood-brain barrier leakage in an R6/2 transgenic mouse model of Huntington’s
价 格:¥电议型 号:T37791产 地:中国大陆
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T37790TAK-700 salt;TAK-700 saltTAK700 (salt)|||TAK 700 (salt)|||TAK-700 salt;TAK700 (salt)|||TAK 700 (salt
TAK-700 salt is a potent and highly selective inhibitor of human 17,20-lyase with an IC50 of 38 nM and is over 1000-fold more selective than other CYPs such as 11-hydroxylase and CYP3A4.
价 格:¥电议型 号:T37790产 地:中国大陆
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T3779Crocin II;西红花苷IICrocin 2|||Crocetin gentiobiosylglucosyl ester|||Tricrocin|||Crocin B;Crocin 2|||西红花
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin II can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin II has antihyperlipidem
价 格:¥电议型 号:T3779产 地:中国大陆
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T377792,3,4,5-Tetrachlorophenol;2,3,4,5-Tetrachlorophenol2,3,4,5-Tetrachlorophenol
2,3,4,5-Tetrachlorophenol is a metabolite of the insecticide γ-lindane.1It is toxic to fathead minnows and rainbow trout (LC50s = 0.496 and 0.304 mg/L, respectively, in tank water).2
价 格:¥电议型 号:T37779产 地:中国大陆
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T36779NG 25 (hydrochloride hydrate);NG 25 (hydrochloride hydrate)NG 25 (hydrochloride hydrate)
NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinases (IC50s = 75.2 nM), as well as CSK, FER, and p38α (IC50s = 56.4, 82.3, and 102 nM, respectively). NG 25 (100 nM) prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectiv
价 格:¥电议型 号:T36779产 地:中国大陆
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T35779Oosporein;OosporeinOosporein
Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1),
价 格:¥电议型 号:T35779产 地:中国大陆
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T34696Spirapril HCl;化合物 T34696BRN4277924|||BRN-4277924|||BRN 4277924|||Spiraprilum|||Spirapril|||Espirapri
Spiropril is an ACE inhibitor antihypertensive drug, which belongs to the bicarboxyl group of ACE inhibitors and is used in the treatment of hypertension.
价 格:¥电议型 号:T34696产 地:中国大陆
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T33779Octyl caprate;化合物 T33779Octyl decanoate;Octyl decanoate
Octyl caprate is a biochemical.
价 格:¥电议型 号:T33779产 地:中国大陆
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T32779Lipid Y;化合物 T32779Lipid Y
Lipid Y is a monosaccharide precursor of E coli lipid A.
价 格:¥电议型 号:T32779产 地:中国大陆
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T31779Fenthiaprop-ethyl;化合物 T31779BRN1166635|||BRN-1166635|||HOE 35 609|||BRN 1166635|||Joker;BRN1166635||
Fenthiaprop-ethyl is a post-emergent herbicide used for the control of grasses and broad-leaved weeds.
价 格:¥电议型 号:T31779产 地:中国大陆
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T31106CS 834;化合物 T31106UNII-H26S03B779|||CS834|||CS-834;UNII-H26S03B779|||CS834|||CS-834
CS 834, a novel oral carbapenem antibiotic, is an ester prodrug of the active metabolite R-95867.
价 格:¥电议型 号:T31106产 地:中国大陆
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T30541BMS-779333;化合物 T30541UNII-3MJN2P4998;UNII-3MJN2P4998
BMS-779333 is a bio-active chemical.
价 格:¥电议型 号:T30541产 地:中国大陆
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T29779AI3-16552;化合物 T29779AI3 16552;AI3 16552
AI3-16552 is an herbicide with irritant effects on the eye and the gastrointestinal system.
价 格:¥电议型 号:T29779产 地:中国大陆
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T28825Sodelglitazar;化合物 T28825GW677954|||GSK-677954;GW677954|||GSK-677954
Sodelglitazar, a PPAR agonist, is used potentially for the treatment of hyperlipidemia and type 2 diabetes.
价 格:¥电议型 号:T28825产 地:中国大陆
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T28779SIM-6080;化合物 T28779SIM-6080
SIM-6080 is a calcium channel antagonist. SIM-6080 inhibits the proliferation of rat aortic myocytes.
价 格:¥电议型 号:T28779产 地:中国大陆
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T28762Setrobuvir;化合物SetrobuvirRO-5466731|||ANA-598|||RG7790|||ANA598|||RG-7790;RO-5466731|||ANA-598|||RG77
Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with IC50s between 4 and 5 nM. setrobuvir shows good binding affinity for SARS-CoV-2 RdRp and induces inhibition of RdRp.
价 格:¥电议型 号:T28762产 地:中国大陆