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产品数:86101
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已选条件
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T9693TBAP-001pancreatic,TBAP-001,lung,Raf kinases,melanoma,Raf,inhibit,TBAP001,TBAP 001,carcinoma,Inhibit
TBAP-001 is a RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay and an IC50 of 18 nM in Cell-Based Phosho-ERK Assay.
价 格:¥电议型 号:T9693产 地:中国大陆
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TN1620Eriocalyxin BEriocalyxin B,inhibit,Apoptosis,Inhibitor
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inhibitor of STAT3, it directly targets STAT3 through a covalent linkage to inhibit the phosphorylation and activation of STAT3 and induces apoptosis of STAT3-dependent tumor cells.
价 格:¥电议型 号:TN1620产 地:中国大陆
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T6498Fenoprofen calcium hydrateApoptosis,Cyclooxygenase,inhibit,Fenoprofen Calcium,Fenoprofen calcium hyd
Fenoprofen calcium hydrate is a non-steroidal anti-inflammatory drug (NSAID).
价 格:¥电议型 号:T6498产 地:中国大陆
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T6732WYE-687mTOR,Mammalian target of Rapamycin,WYE-687,Phosphoinositide 3-kinase,WYE687,PI3K,WYE 687,inhi
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6732产 地:中国大陆
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T82275’-MethylthioadenosineMTA,MTAP?,MTAP+,NIH3T3,5’ Methylthioadenosine,inhibit,SAM,5’Methylthioadenosin
5´-Methylthioadenosine is produced from S-adenosylmethionine and behaves as a powful inhibitory product.
价 格:¥电议型 号:T8227产 地:中国大陆
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T7817Aprocitentaninhibit,Endothelin Receptor,ACT132577,Aprocitentan,Inhibitor,ACT 132577
Aprocitentan is ETA and ETB antagonist .
价 格:¥电议型 号:T7817产 地:中国大陆
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T7221SatraplatinBMY 45594,DNA Alkylator/Crosslinker,BMS-182751,Satraplatin,BMY-45594,JM 216,inhibit,Inhib
Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies.
价 格:¥电议型 号:T7221产 地:中国大陆
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T9521CHR-6494 TFACHR-6494,inhibit,apoptosis,Haspin Kinase,NRAS mutant melanoma cells,CHR 6494,mitotic cat
CHR-6494 TFA is a potent haspin inhibitor, with an?IC50?of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the?apoptosis?of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be used in the research of cancer
价 格:¥电议型 号:T9521产 地:中国大陆
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T6S0052ChelerythrineBcl-2 Family,Apoptosis,Protein kinase C,PKC,Inhibitor,Chelerythrine,inhibit,Autophagy
1. Chelerythrine may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiproliferative and antitumor effects.
价 格:¥电议型 号:T6S0052产 地:中国大陆
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T6312R547Glycogen synthase kinase 3,kinase,multiple,tumor,cyclin-dependent,R547,Apoptosis,Cyclin dependen
R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.
价 格:¥电议型 号:T6312产 地:中国大陆
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T8788NaptalamInhibitor,Alanap-1,transport inhibitor,inhibit,Alanap 1,Alanap1,maize,polar auxin,leaf margi
Naptalam is an herbicide.Naptalam is a dicarboxylic acid monoamide which results from addition of one equivalent of 1-naphthylamine to phthalic anhydride. It is a dicarboxylic acid monoamide, a carboxylic acid and a N-(1-naphthyl)carboxamide. It is a conjugate acid of a naptalamate.
价 格:¥电议型 号:T8788产 地:中国大陆
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T828814-Deoxyandrographolideplatelet activating factor,rat,bovine neutrophils,14 Deoxyandrographolide,Cal
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
价 格:¥电议型 号:T8288产 地:中国大陆
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T6S2315Polyphyllin VIPolyphyllin VI,inhibit,Pyroptosis,Apoptosis,Inhibitor
1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.
价 格:¥电议型 号:T6S2315产 地:中国大陆
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T73711-Naphthyl PP1 hydrochloride1 Naphthyl PP1 hydrochloride,Src,1Naphthyl PP1 hydrochloride,1-Naphthyl
1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src
价 格:¥电议型 号:T7371产 地:中国大陆
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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格:¥电议型 号:T7414产 地:中国大陆
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TN1739Homodihydrocapsaicin Iphytotoxic,Capsicum annuum,Capsaicinoid,Homodihydrocapsaicin I,Inhibitor,inhib
Homodihydrocapsaicin I is a natural product from Capsicum annuum L.
价 格:¥电议型 号:TN1739产 地:中国大陆
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T8901YUM70Heat shock proteins,YUM70,HSP,cancer,pancreatic,reticulum,Apoptosis,GRP78,YUM-70,stress-mediate
YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
价 格:¥电议型 号:T8901产 地:中国大陆
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T7001TIC10TIC 10,Tumor Necrosis Factor Receptor,inhibit,ONC201,Inhibitor,TNF Receptor,Apoptosis,TNFR,ONC
TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
价 格:¥电议型 号:T7001产 地:中国大陆
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T6921ONO-4059 analogInhibitor,Btk,inhibit,ONO4059,ONO 4059,Apoptosis,ONO 4059 analog,Bruton tyrosine kina
ONO-4059 analogue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.
价 格:¥电议型 号:T6921产 地:中国大陆
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T8006Oncrasin-1Oncrasin-1,Oncrasin1,Ras,Apoptosis,Oncrasin 1,inhibit,Inhibitor
Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations
价 格:¥电议型 号:T8006产 地:中国大陆