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产品数:86101
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T9179CLP-3094LNCaP,Inhibitor,Androgen Receptor,CLP3094,inhibit,prostate,CLP 3094,resistance,CLP-3094,anti
CLP-3094 is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GPR142 antagonist.
价 格:¥电议型 号:T9179产 地:中国大陆
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T6557KU-0060648mTOR,inhibit,KU-0060648,Phosphoinositide 3-kinase,Inhibitor,Mammalian target of Rapamycin,
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
价 格:¥电议型 号:T6557产 地:中国大陆
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T38852LTRAP-6 amide acetateTRAP6 amide acetate,TRAP 6 amide acetate
TRAP-6 amide acetate is a?PAR-1 thrombin receptor?agonist peptide[1].
价 格:¥电议型 号:T38852L产 地:中国大陆
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TQ0082AticaprantCERC 501,inhibit,LY2456302,Opioid Receptor,Aticaprant,Inhibitor,CERC501,LY 2456302
Aticaprant (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).
价 格:¥电议型 号:TQ0082产 地:中国大陆
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T9541CTBHATs,Inhibitor,neurons,CTB,Apoptosis,MCF-7 cell,cancer,potent,HAT,autophagic flux,inhibit,Histone
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.
价 格:¥电议型 号:T9541产 地:中国大陆
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T6561Laquinimodinhibit,multiple sclerosis,relapsing remitting,carboxamide,Nuclear factor-kappaB,Apoptosis
Laquinimod is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy.
价 格:¥电议型 号:T6561产 地:中国大陆
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TN2230Soyasaponin BaInhibitor,Soyasaponin Ba,inhibit
Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase.
价 格:¥电议型 号:TN2230产 地:中国大陆
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T13867RH01386RH 01386,βTC6 cells,RH01386,RH-01386,inhibit,Apoptosis,Inhibitor,type 2 diabetes,β cell
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.
价 格:¥电议型 号:T13867产 地:中国大陆
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T6S0840EngeletinNuclear factor-kappaB,Engeletin,inhibit,NF-κB,Inhibitor,Nuclear factor-κB
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
价 格:¥电议型 号:T6S0840产 地:中国大陆
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TQ0060LY2857785Cyclin dependent kinase,LY 2857785,CDK,Apoptosis,LY2857785,Inhibitor,inhibit,LY-2857785
LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).
价 格:¥电议型 号:TQ0060产 地:中国大陆
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T17117Tonapofylline
Tonapofylline is an orally active and selective antagonist of the A1 adenosine receptor (Ki: 7.4 nM for human A1). Tonapofylline can be used in studies about heart failure.
价 格:¥电议型 号:T17117产 地:中国大陆
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TN1413AtranorinAP-1,Atranorin,Ras,metabolite,secondary,Wnt,inhibit,β-catenin,Lichen,STAT,Endogenous Metabo
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical, also, it will exert cytoprotective effects on cells under oxidative stress induced by H(2)O(2).
价 格:¥电议型 号:TN1413产 地:中国大陆
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T94326-Bromo-2-naphthol6Bromo2naphthol,6 Bromo 2 naphthol
6-Bromo-2-naphthol is?an electrophilic carbene intermediate.
价 格:¥电议型 号:T9432产 地:中国大陆
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TP2363LAcetyl tetrapeptide-2 AcetateAcetyl tetrapeptide2 Acetate,Acetyl tetrapeptide 2 Acetate
Acetyl tetrapeptide-2 Acetate is most commonly used as a skin conditioner. Acetyl tetrapeptide-2 Acetate is done by compensating for hormone loss in the skin, especially collagen, providing somewhat of a plumping effect to the skin.
价 格:¥电议型 号:TP2363L产 地:中国大陆
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T6919OmaveloxoloneInhibitor,Omaveloxolone,Apoptosis,RTA 408,RTA408,ERIS,STING,inhibit,Stimulator of Inter
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
价 格:¥电议型 号:T6919产 地:中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格:¥电议型 号:T6481产 地:中国大陆
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T9218AndrograpaninInhibitor,chemotaxis,p38 MAPK,leukocyte,SDF-1α,Andrograpanin,PBL,inhibit,Jurkat,anti-in
Andrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
价 格:¥电议型 号:T9218产 地:中国大陆
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T6S0119DauricineNuclear factor-κB,Inhibitor,inhibit,Dauricine,Nuclear factor-kappaB,Apoptosis,NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profil
价 格:¥电议型 号:T6S0119产 地:中国大陆
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T98967-Methoxy-1-naphthylacetonitrile7Methoxy1naphthylacetonitrile,7 Methoxy 1 naphthylacetonitrile
7-Methoxy-1-naphthylacetonitrile is one of the impurities of agomelatine, an antidepressant.
价 格:¥电议型 号:T9896产 地:中国大陆
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T6S1371Isovitexininhibit,Isovitexin,Nuclear factor-kappaB,Inhibitor,Nuclear factor-κB,NF-κB,JNK
1. Isovitexin exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.
价 格:¥电议型 号:T6S1371产 地:中国大陆