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产品数:86101
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T9117BSJ-4-116CDK,degrader,antiproliferative,inhibit,Kelly,C1039F,BSJ 4 116,Cyclin dependent kinase,PROTA
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly(adenylation).
价 格:¥电议型 号:T9117产 地:中国大陆
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TN5888Toddaculininhibit,Toddaculin,osteoclast,Inhibitor,differentiation,leukemic,Apoptosis,osteoblast,anti
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can induce differentiation and mineralization of osteoblasts by regulating differentiation factors. Toddaculine also may serve as a pharmacological prototype for the development of novel anti-leukemic agents, it displays a dual effect as a cell differentiating agent and apoptosis induc
价 格:¥电议型 号:TN5888产 地:中国大陆
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T9196IACS-13909antiproliferative,RTK,IACS13909,inhibit,SHP2,pMEK,anticancer,Inhibitor,MAPK,IACS 13909,pER
IACS-13909, a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.
价 格:¥电议型 号:T9196产 地:中国大陆
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T8122Mafenide AcetateMafenide,Mafenide Acetate,Antibiotic,Bacterial,Inhibitor,inhibit
Mafenide Acetate is a sulfonamide-type medication inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.
价 格:¥电议型 号:T8122产 地:中国大陆
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TN3669Cis-N-FeruloyltyramineCis N Feruloyltyramine,CisNFeruloyltyramine
Cis-N-Feruloyltyramine shows cytotoxicity against the P-388 cancer cell line. N-cis-Feruloyltyramine and N-trans-Feruloyltyramine are the inhibitors of in vitro prostaglandin (PG) synthesis.
价 格:¥电议型 号:TN3669产 地:中国大陆
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T9073SRS16-86IRI,SRS16-86,Inhibitor,ferrostatin,SRS-16-86,ischemia-reperfusion injury,SCI,spinal cord inj
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of?ferroptosis.
价 格:¥电议型 号:T9073产 地:中国大陆
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T36683VedaprofenVedaprofen,Inhibitor,nonsteroidal,PM150,PM-150,Escherichia coli,inhibit,CERM-10202,CERM102
Vedaprofen inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.
价 格:¥电议型 号:T36683产 地:中国大陆
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TN10511-Caffeoylquinic acidinhibit,NF-κB,Nuclear factor-kappaB,Nuclear factor-κB,1-Caffeoylquinic acid,Inh
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal.
价 格:¥电议型 号:TN1051产 地:中国大陆
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T7089SGC2085SGC2085,SGC 2085,Inhibitor,inhibit,SGC-2085,Histone Methyltransferase
SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).
价 格:¥电议型 号:T7089产 地:中国大陆
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T6S2391L-Chicoric Acidreplication,Inhibitor,L-Chicoric Acid,HIV Integrase,L Chicoric Acid,dicaffeoyltartari
L-Chicoric acid has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may reduce acute alcohol-induced steatosis in mice through interfering with the induction of iNOS and iNOS-dependent signaling cascades in the liver. 3. L-Chicoric acid inhibited cell viability and induced apoptosis in 3T3-L1 preadipocytes which was characterized by chromatin condensation and poly ADP-ribose-poly
价 格:¥电议型 号:T6S2391产 地:中国大陆
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T9988WAY-328173osteoblasts,β-catenin,WAY328173,Beta catenin,cells,differentiation,transmission,inhibit,In
WAY-328173 is a Wnt/beta-catenin agonist.
价 格:¥电议型 号:T9988产 地:中国大陆
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T13619Cloperastine fendizoate
Cloperastine fendizoate inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).
价 格:¥电议型 号:T13619产 地:中国大陆
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T6S15253,4-Dicaffeoylquinic acidnaturally,DNA,3,4Dicaffeoylquinic acid,Influenza Virus,protective,antioxida
1. Isochlorogenic acid B has antioxidant activity.
价 格:¥电议型 号:T6S1525产 地:中国大陆
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TP1073Neuropeptide W-23(human)Neuropeptide W23(human),hypetension,anorexigenic effect,Neuropeptide W 23(hu
Neuropeptide W-23(human) is an endogenous ligand for NPBW1 and NPBW2.
价 格:¥电议型 号:TP1073产 地:中国大陆
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TN2111PruninHEVs,HEV,RNA,HRVs,Prunin,Inhibitor,Phosphatase,infection,Enterovirus,inhibit,synthesis,anti-di
Prunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp. Prunin exhibits a markedly enhanced solubility compared to naringenin and naringin while maintaining the in vitro inhibition of HMG-CoA reductase.
价 格:¥电议型 号:TN2111产 地:中国大陆
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T19676Tributyrinantiproliferative,fatty acid triglyceride,Inhibitor,proapoptotic,prodrug,inhibit,21920,Tri
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent proapoptotic, antiproliferative, and differentiation-inducing effects.
价 格:¥电议型 号:T19676产 地:中国大陆
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T7282Tenofovir alafenamide hemifumarateInhibitor,Human immunodeficiency virus,inhibit,Tenofovir alafenami
Tenofovir alafenamide fumarate (TAF) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV)
价 格:¥电议型 号:T7282产 地:中国大陆
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T6524GW0742GW0742,inhibit,GW 610742,Inhibitor,PPAR,Peroxisome proliferator-activated receptors,GW-0742,GW
GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).
价 格:¥电议型 号:T6524产 地:中国大陆
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T9698UC2288Attenuator,786-O,Inhibitor,UC-2288,MDM-2/p53,inhibit,UC2288,ovarian,RCC,HK2,UC 2288,p21,sorafe
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.
价 格:¥电议型 号:T9698产 地:中国大陆
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T24579Oxyfedrine L-form HCl
Oxyfedrine L-form HCl is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.
价 格:¥电议型 号:T24579产 地:中国大陆