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T4039BIBB 515BIBB 515,Inhibitor,OSC,inhibit,cyclase,effect,metabolism,LDL,BIBB-515,2,3-oxidosqualene,BIBB
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2, 3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. Total cholesterol was reduced by 19% in normolipemic hamsters at a dose of 55 mg/kg/day for 11 days and 25% in hyperlipemic
价 格：￥电议型 号：T4039产 地：中国大陆
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T6743(E/Z)-4-Hydroxytamoxifen(E/Z)4Hydroxytamoxifen,Inhibitor,inhibit,(E/Z) 4 Hydroxytamoxifen,Endogenous
4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.
价 格：￥电议型 号：T6743产 地：中国大陆
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T9419FesoterodineDesfesoterodine,Fesoterodine,OAB,muscarinic,overactive,Inhibitor,SPM7605,mAChR,orally,5-
Fesoterodine is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB).
价 格：￥电议型 号：T9419产 地：中国大陆
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T371924-Methylumbelliferyl-α-D-Galactopyranoside
4-Methylumbelliferyl-α-D-Galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase. In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease.
价 格：￥电议型 号：T37192产 地：中国大陆
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T8387Alectinib hydrochlorideCluster of differentiation 246,AF-802,CH5424802,AF802,Alectinib hydrochloride
Alectinib hydrochloride is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)
价 格：￥电议型 号：T8387产 地：中国大陆
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T60050ANT3310ANT-3310,ANT3310,inhibit,SBL,infection,CRE,β-lactam antibiotic,ANT 3310,Bacterial,OXA enzymes
ANT3310 is an inhibitor of broad-spectrum covalent Serine β-Lactamase with IC50s ranging from 1 nM to 175 nM for AmpC, CTX-M-15, TEM-1, OXA-48, OXA-23, and KPC-2. ANT3310 can be used in studies about bacterial infection.
价 格：￥电议型 号：T60050产 地：中国大陆
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T8360β-Pineneβ-Pinene,Inhibitor,infectious,IBV,antimicrobial,Turpentine,inhibit,virus,Bacterial,β Pinene,
(-)-β-Pinene is inhibit infectious bronchitis virus (IBV) with an IC50 of 1.32 mM,with antimicrobial activity
价 格：￥电议型 号：T8360产 地：中国大陆
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TN1818Kaempferol 3-O-β-D-glucuronidecytokine,Inhibitor,inhibit,mice,secretion,Interleukin Related,RAW 264.
Kaempferol 3-O-β-D-glucuronidee has antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α?-glucuronidase from various human cells.
价 格：￥电议型 号：TN1818产 地：中国大陆
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T79347-Methylcoumarinantioxidant effect,Inhibitor,7-Methylcoumarin,coumarin,7Methylcoumarin,inhibit,7 Met
7-Methylcoumarin with strong hepatoprotective activity.
价 格：￥电议型 号：T7934产 地：中国大陆
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TN6719Kaempferol-3-O-β-D-glucosyl(1-2)rhamnosideKaempferol 3 O β D glucosyl(1 2)rhamnoside,Kaempferol3OβDg
Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside is a natural peoduct isolated from Arabian jasmine
价 格：￥电议型 号：TN6719产 地：中国大陆
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T16909Sorafenib-d3
Sorafenib-d3 is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).
价 格：￥电议型 号：T16909产 地：中国大陆
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T8236RHC 80267COX,mAChR,Platelet,mono- acylglycerol acyltransferase,Cyclooxygenase,Acyltransferase,Phosph
RHC 80267 is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)
价 格：￥电议型 号：T8236产 地：中国大陆
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TN1525Convallatoxinpsoriasis,Nuclear factor-κB,P-gp,Inhibitor,anti-proliferative,colitic,anti-inflammatory
Convallatoxin is a natural product.
价 格：￥电议型 号：TN1525产 地：中国大陆
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TN2190Scoulerineproliferation,Inhibitor,cancer,Beta-secretase,Scoulerine,Apoptosis,inhibit,microtubule,cyc
Scoulerine is an inhibitor of ?-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.
价 格：￥电议型 号：TN2190产 地：中国大陆
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T8756KRAS inhibitor-9non-small,proliferation,inhibit,KRAS inhibitor 9,KRAS inhibitor9,cytotoxicity,Apopto
KRAS inhibitor-9 is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSCLC cells with KRAS mutation but not normal lung cells
价 格：￥电议型 号：T8756产 地：中国大陆
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T8768MM-102 TFAMM102,HMTase Inhibitor IX,MM-102,MM 102 TFA,MM 102,inhibit,MM102 TFA,Histone Methyltransfe
MM-102 TFA is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM. MM-102 compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WDR5) and results in the inhibition of MLL1 H3K4 histone methyltransferase (HMT) activity. Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embry
价 格：￥电议型 号：T8768产 地：中国大陆
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T8381AmodiaquineCCL2,Nurr1,IL-1β,Histone Methyltransferase,Amodiaquine,Amodiaquin,inhibit,Inhibitor,anti-
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
价 格：￥电议型 号：T8381产 地：中国大陆
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TN1691GlabrolInhibitor,mono- acylglycerol acyltransferase,Acyltransferase,Diacylglycerol acyltransferase,i
Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
价 格：￥电议型 号：TN1691产 地：中国大陆
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TN5137TetramethylkaempferolTetramethylkaempferol
Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempferol can concentration-dependently enhance the accumulation of triglyceride, a marker of adipogenesis.
价 格：￥电议型 号：TN5137产 地：中国大陆
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TN7097Tetrahydrodehydrodiconiferyl alcoholTetrahydrodehydrodiconiferyl alcohol
Tetrahydrodehydrodiconiferyl alcohol is a natural product.
价 格：￥电议型 号：TN7097产 地：中国大陆
